Lipidomics: An analysis of cellular lipids by ESI-MS

• Published in: Methods (San Diego, Calif.) Vol. 39; no. 2; pp. 92 - 103
• Main Authors: Milne, Stephen, Ivanova, Pavlina, Forrester, Jeffrey, Alex Brown, H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2006
• Subjects: Biochemistry - methods; Computational Biology - methods; Electrospray ionization; Glycerophospholipids; Lipid Metabolism; Lipidomics; Lipids - analysis; Mass spectrometry; Phospholipids - isolation & purification; Signal Transduction; Spectrometry, Mass, Electrospray Ionization - instrumentation; Spectrometry, Mass, Electrospray Ionization - methods; Lipidomics; Glycerophospholipids; Mass spectrometry; Electrospray ionization

Recognition of the importance of lipid signaling in cellular function has led to rapid progress in the technology of lipid analysis. Measurements of lipid species changes are central to defining the networks of cell signaling (e.g., receptor activation by hormones or drugs) and lipids are involved i...