TSH response to TRH and EEG sleep in non-bipolar major depression: a multivariate approach

• Published in: European neuropsychopharmacology Vol. 4; no. 4; pp. 517 - 525
• Main Authors: Hubain, Ph.P., Staner, L., Dramaix, M., Kerkhofs, M., van Veeren, C., Papadimitriou, G., Mendlewicz, J., Linkowski, P.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.1994
• Subjects: Adult; Age Factors; Aged; Depressive Disorder - blood; Depressive Disorder - psychology; Electroencephalography - drug effects; Endogenous subtype; Female; Humans; Major depressive disorder; Male; Middle Aged; Multivariate Analysis; Newcastle scale; Psychiatric Status Rating Scales; Psychotic subtype; Sex Characteristics; Sleep; Sleep - drug effects; Thyrotropin - blood; Thyrotropin-Releasing Hormone - pharmacology; TSH response to TRH; Newcastle scale; Sleep; Major depressive disorder; Endogenous subtype; Psychotic subtype; TSH response to TRH

The TSH response to TRH and selected sleep EEG variables were studied in a homogenous sample of 280 non-bipolar major depressed inpatients (95 males and 185 females). The TSH was blunted in 28% of the sample. Δmax TSH was correlated negatively with age, Hamiltoninating scale, Newcastle scale, percen...