Biosynthesis of ubiquinone and ubichromenol in vitamin A-deficient rats

• Published in: Biochimica et biophysica acta Vol. 115; no. 2; pp. 294 - 305
• Main Authors: Joshi, V.C., Ramasarma, T.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 28.02.1966
• Subjects: Animals; Benzopyrans - biosynthesis; In Vitro Techniques; Intestinal Mucosa - metabolism; Kidney - metabolism; Liver - metabolism; Mevalonic Acid - metabolism; Rats; Ubiquinone - biosynthesis; Vitamin A Deficiency - metabolism

1. 1. The concentrations of ubiquinone and ubichromenol increased in the livers, but not in the intestines and kidneys, of rats maintained on a diet deficient in vitamin A. 2. 2. After short time intervals ( e.g. 2 h) following administration of the tracer, incorporation of [2- 14C]mevalonate into u...