Use of norfloxacin in the treatment of acute diarrheal disease

• Published in: The American journal of medicine Vol. 82; no. 6; pp. 79 - 83
• Main Authors: Dupont, Herbert L., Corrado, Michael L., Sabbaj, Jacobo
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 26.06.1987
• Subjects: Acute Disease; Adult; Child; Clinical Trials as Topic; Diarrhea - drug therapy; Diarrhea - microbiology; Drug Combinations - adverse effects; Drug Combinations - therapeutic use; Feces - microbiology; Humans; Microbial Sensitivity Tests; Norfloxacin - administration & dosage; Norfloxacin - adverse effects; Norfloxacin - therapeutic use; Random Allocation; Sulfamethoxazole - adverse effects; Sulfamethoxazole - therapeutic use; Trimethoprim - adverse effects; Trimethoprim - therapeutic use; Trimethoprim, Sulfamethoxazole Drug Combination

In studies conducted in seven countries, 392 persons with acute diarrhea were enrolled and randomly assigned to one of three regimens. In order to compare the effectiveness of various therapies for acute gastroenteritis, patients were treated for five days with either norfloxacin, 400 mg twice daily...