The effects of a selective Alpha-1 adrenergic blockade on the activity of adipose tissue lipoprotein lipase in female hamsters

• Published in: Life sciences (1973) Vol. 57; no. 7; pp. 705 - 713
• Main Authors: Desfaits, Anne-Cécile, Lafond, Julie, Savard, Roland
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 1995
• Subjects: adipose tissue; Adipose Tissue - drug effects; Adipose Tissue - enzymology; Adipose Tissue, Brown - drug effects; Adipose Tissue, Brown - enzymology; Animals; Calcium - blood; Calcium - metabolism; Cricetinae; doxazosin; Doxazosin - pharmacology; Enzyme Activation; Female; Glycerol - blood; hamster; lipoprotein lipase; Lipoprotein Lipase - metabolism; Mesocricetus; Muscle, Skeletal - drug effects; Muscle, Skeletal - enzymology; Myocardium - enzymology; phenylephrine; Phenylephrine - pharmacology; Triglycerides - blood; adipose tissue; doxazosin; lipoprotein lipase; phenylephrine; hamster

Lipoprotein lipase, is an enzyme responsible for the hydrolysis of triacylglycerols at the surface of endothelial cells. Its regulation is not completely elucidated and seems, among other things, under the influence of the sympathetic nervous system. The adrenergic regulation of lipoprotein lipase a...