Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome

• Published in: Pediatric nephrology (Berlin, West) Vol. 20; no. 11; pp. 1655 - 1656
• Main Authors: van Vuurden, Dannis G, Plötz, Frans B, de Jong, Miranda, Bokenkamp, Arend, van Wijk, Joanna A E
• Format: Journal Article
• Language: English
• Published: Germany Springer 01.11.2005; Springer Nature B.V
• Subjects: Autoantibodies - blood; Child, Preschool; ELAV Proteins - immunology; Humans; Male; Nephrology; Neuroblastoma - immunology; Paraneoplastic syndromes; Paraneoplastic Syndromes, Nervous System - immunology; Paraneoplastic Syndromes, Nervous System - therapy; Plasma Exchange; Spinal Cord Neoplasms - immunology; Tumors

A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction. Total plasma exchange (TPE) resulted eventually in a reduction of autoantibody levels, but, more importantly, led to improvement...