Evidence for increased endogenous dopaminergic inhibition of aldosterone secretion in prolactinoma

• Published in: Hormone and metabolic research Vol. 18; no. 10; p. 704
• Main Authors: Jungmann, E, Schwedes, U, Althoff, P H, Rosak, C, Schöffling, K
• Format: Journal Article
• Language: English
• Published: Germany 01.10.1986
• Subjects: Adult; Aldosterone - secretion; Dopamine - physiology; Female; Humans; Male; Metoclopramide - pharmacology; Middle Aged; Pituitary Neoplasms - secretion; Prolactin - secretion

Aldosterone responsiveness to consecutive i.v. injections of metoclopramide 1 mg, 2.5 mg and 10 mg was studied in 8 patients with prolactinoma and normally preserved adrenal function and in 14 healthy volunteers. In the patients, aldosterone response to metoclopramide 1 mg was blunted. After metoclo...