Incidence and Prevalence of Syphilitic Uveitis and Associated Ocular Complications in the TriNetX Database

• Published in: American journal of ophthalmology Vol. 277; pp. 387 - 394
• Main Authors: Zhou, Lucy R., Kirupaharan, Nila, Berkenstock, Meghan K.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2025
• Subjects: Adult; Aged; Databases, Factual; Eye Infections, Bacterial - diagnosis; Eye Infections, Bacterial - epidemiology; Eye Infections, Bacterial - microbiology; Female; Humans; Incidence; Male; Middle Aged; Prevalence; Retrospective Studies; Syphilis - complications; Syphilis - diagnosis; Syphilis - epidemiology; Syphilis - microbiology; United States - epidemiology; Uveitis - diagnosis; Uveitis - epidemiology; Uveitis - microbiology; Young Adult; United States; SD; ICD-10; HCPCS; CDC; STI; IV; US

•Positive treponemal and non-treponemal tests identified cases of syphilitic uveitis in the TriNetX database.•The cumulative incidence and prevalence from 2013-2024 were 0.36 and 0.27 per 100,000, respectively.•HIV co-infection occurred in 32.49% and 27.85% had low vision or blindness.•A timely diag...