Fabrication of radiopaque drug-eluting beads based on Lipiodol/biodegradable-polymer for image-guided transarterial chemoembolization of unresectable hepatocellular carcinoma

• Published in: Polymer degradation and stability Vol. 175; p. 109106
• Main Authors: Okamoto, Yutaka, Hasebe, Terumitsu, Bito, Kenta, Yano, Kosaku, Matsumoto, Tomohiro, Tomita, Kosuke, Hotta, Atsushi
• Format: Journal Article
• Language: English
• Published: London Elsevier Ltd 01.05.2020; Elsevier BV
• Subjects: Arteries; Attenuation; Biodegradability; Blood vessels; Computed tomography; Drug delivery systems; Drug-eluting bead; Embolization; Lipiodol; Liver cancer; Microfluidic devices; Microspheres; Molecular weight; Object recognition; Platinum; Polycaprolactone; Polymers; Radiopacity; Submerging; Tomography; Transarterial chemoembolization; Tumors; Weight loss; Lipiodol; Radiopacity; Biodegradability; Polycaprolactone; Drug-eluting bead; Transarterial chemoembolization

New radiopaque/biodegradable drug-eluting beads (DEBs) for transarterial chemoembolization (TACE) were fabricated using Lipiodol and polycaprolactone (PCL) (Lipiodol/PCL beads) through a microfluidic device. TACE is the most extensively-applied therapy for unresectable hepatocellular carcinoma (HCC)...