Prediction of Early Treatment Response in Multiple Myeloma Using MY-RADS Total Burden Score, ADC, and Fat Fraction From Whole-Body MRI: Impact of Anemia on Predictive Performance

• Published in: American journal of roentgenology (1976) Vol. 218; no. 2; pp. 310 - 319
• Main Authors: Dong, Huazheng, Huang, Wenyang, Ji, Xiaodong, Huang, Lixiang, Zou, Dehui, Hao, Mu, Deng, Shuhui, Shen, Zhiwei, Lu, Xiudi, Wang, Jian, Song, Zhiyi, Zhang, Xuening, Xue, Huadan, Xia, Shuang
• Format: Journal Article
• Language: English
• Published: United States 01.02.2022
• Subjects: Adipose Tissue - diagnostic imaging; Anemia - complications; Cost of Illness; Female; Humans; Magnetic Resonance Imaging - methods; Male; Middle Aged; Multiple Myeloma - complications; Multiple Myeloma - diagnostic imaging; Multiple Myeloma - pathology; Predictive Value of Tests; Radiology Information Systems; Retrospective Studies; Treatment Outcome; Whole Body Imaging - methods; multiple myeloma; tumor burden; treatment response; whole-body MRI; anemia

. The recently released Myeloma Response Assessment and Diagnosis System (MY-RADS) for multiple myeloma (MM) evaluation using whole-body MRI (WB-MRI) describes the total burden score. However, assessment is confounded by red bone marrow hyperplasia in anemia. . The purpose of this study is to assess...