Dengue Virus Ribonucleic Acid Detection Rates in Blood Donors Correlate With Local Infection Incidences During a Dengue Outbreak in Taiwan

• Published in: The Journal of infectious diseases Vol. 225; no. 9; pp. 1504 - 1512
• Main Authors: Chen, Yun-Yuan, Lu, Chi-Te, Tsai, Mei-Hua, Yang, Cheng-Fen, Shu, Pei-Yun, Wu, Chia-Wen, Chen, Jen-Wei, Hung, Chi-Ming, Wei, Sheng-Tang, Hou, Sheng-Mou, Chen, Pei-Jer
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 04.05.2022
• Subjects: Alanine; Alanine transaminase; Antibodies, Viral; Blood & organ donations; Blood Donors; Blood transfusion; Dengue; Dengue fever; Dengue Virus - genetics; Disease Outbreaks; Disease transmission; DNA-directed RNA polymerase; Epidemics; Humans; Immunoglobulin G; Immunoglobulin M; Incidence; Infections; Ribonucleic acid; RNA; RNA, Viral - genetics; Taiwan - epidemiology; Taiwan; blood safety; transfusion-transmitted infection; dengue

Abstract Background Evidence for mitigation of transfusion-transmitted dengue informed by surveillance data is lacking. In this study, we evaluated the risk of positive dengue viral (DENV) ribonucleic acid (RNA) from blood transfusions during a large outbreak in Taiwan. Methods Serum collected from...