β‑glucan vaccine adjuvant approach for cancer treatment through immune enhancement (B‑VACCIEN) in specific immunocompromised populations (Review)

• Published in: Oncology reports Vol. 47; no. 1
• Main Authors: Ikewaki, Nobunao, Dedeepiya, Vidyasagar, Raghavan, Kadalraja, Rao, Kosagi-Sharaf, Vaddi, Suryaprakash, Osawa, Hiroshi, Kisaka, Tomohiko, Kurosawa, Gene, Srinivasan, Subramaniam, Kumar, Seydunganallu, Senthilkumar, Rajappa, Iwasaki, Masaru, Preethy, Senthilkumar, Abraham, Samuel
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications UK Ltd 01.01.2022
• Subjects: Adjuvants, Vaccine - administration & dosage; Aging; Animals; Antigens; beta-Glucans - immunology; Cancer therapies; Chemotherapy; Cytotoxicity; Diabetes; Disease prevention; DNA damage; Health risk assessment; Humans; Hyperglycemia; Hypothalamus; Immune system; Immunocompromised Host - immunology; Inflammation; Metabolic disorders; Mortality; Neoplasms - immunology; Neoplasms - prevention & control; Older people; Phytochemicals; Prostate cancer; Radiation therapy; Surgery; Vaccines; vaccine adjuvant; cancer; β‑glucan; immune weakness

The incidence of cancer, which is the second leading cause of mortality globally, continues to increase, although continued efforts are being made to identify effective treatments with fewer side‑effects. Previous studies have reported that chronic microinflammation, which occurs in diseases, includ...