Anti-LGI1 Antibody-Associated Encephalitis Misdiagnosed as Schizophrenia: A Case Report

• Published in: Schizophrenia bulletin Vol. 50; no. 6; pp. 1273 - 1276
• Main Authors: Zhang, Jin-he, Fu, Bing-bing, Wang, Wei, Sun, Cong-cong, Xu, Jin-jie
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 08.11.2024
• Subjects: Antibodies; Autoantibodies - blood; Autoantibodies - cerebrospinal fluid; Case reports; Diagnostic Errors; Encephalitis; Encephalitis - diagnosis; Encephalitis - immunology; Humans; Intracellular Signaling Peptides and Proteins - immunology; Male; Medical imaging; Middle Aged; Neuroimaging; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - immunology; autoimmune encephalitis; psychiatric symptoms; magnetic resonance imaging; LGI1 antibody-associated encephalitis; cerebrospinal fluid tests; immunotherapy

Abstract Anti-leucine-rich glioma-inactivated 1 (LGI1) antibody-associated encephalitis is a rare but clinically significant form of autoimmune encephalitis, predominantly affecting middle-aged men. Its heterogeneous clinical presentation often leads to misdiagnosis, commonly as other neurological o...