Cellular Senescence and Extracellular Vesicles in the Pathogenesis and Treatment of Obesity—A Narrative Review - Liang, Yicong; Kaushal, Devesh; Wilson, Robert Beaumont (International journal of molecular sciences, 2024)
Keywords: Adipocytes; Adipocytes - metabolism; Aging; Animals; Apoptosis; Ataxia; Body composition; Body mass index; Cellular Senescence; Cyclin-dependent kinases; Diabetes; Diet; Disease; DNA methylation; Energy; Exosomes - metabolism; Extracellular Vesicles - metabolism; Gastrointestinal surgery; Humans; Hypotheses; Kinases; Metabolic syndrome; Mitochondria; Obesity; Obesity - metabolism; Obesity - pathology; Oils & fats; Overweight; Oxidative stress; Physiology; Proteins; Reactive oxygen species; Senescence; Weight control; hypertrophic obesity; adiponectin; epigenome; autophagy; extracellular vesicles; ER stress; VAT; SASP; p53; metabolic syndrome; SIRT-1; DDR; cellular senescence; NEFA; exosomes; ROS; lipotoxicity; Western-type diet; senolytic; AMPK; miRNA; aging; obesogenic environment; insulin resistance