MRI‐based measurements of whole‐brain global cerebral blood flow: Comparison and validation at 1.5T and 3T

• Published in: Journal of magnetic resonance imaging Vol. 48; no. 5; pp. 1273 - 1280
• Main Authors: Chen, Chun‐Ming, Huang, Yen‐Chih, Shih, Cheng‐Ting, Chen, Yung‐Fang, Peng, Shin‐Lei
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2018
• Subjects: Blood flow; Brain; brain volume; Cerebral blood flow; Correlation analysis; Correlation coefficient; Correlation coefficients; Data acquisition; Females; Field strength; flow quantification; Magnetic resonance imaging; Neuroimaging; Parenchyma; phase‐contrast magnetic resonance imaging; Population (statistical); Population studies; Regression analysis; Reproducibility; Statistical analysis; Statistical tests; Substantia alba; phase-contrast magnetic resonance imaging; flow quantification; brain volume; field strength; reproducibility

Background Whole‐brain global cerebral blood flow (CBF) determined by MRI techniques, calculated using total CBF (TCBF) from phase‐contrast MRI (PC‐MRI), and brain parenchyma volume (BPV) from T1‐weighted image, have become increasingly popular in many applications. Purpose/Hypothesis To determine i...