First clinical evaluation of a new long-term subconjunctival glucose sensor

• Published in: Journal of diabetes science and technology Vol. 6; no. 4; pp. 875 - 883
• Main Authors: Müller, Achim Josef, Knuth, Monika, Nikolaus, Katharina Sibylle, Herbrechtsmeier, Peter
• Format: Journal Article
• Language: English
• Published: United States Diabetes Technology Society 01.07.2012
• Subjects: Adult; Biosensing Techniques - instrumentation; Biosensing Techniques - methods; Blood Glucose - analysis; Blood Glucose Self-Monitoring - instrumentation; Blood Glucose Self-Monitoring - methods; Circadian Rhythm - physiology; Concanavalin A - analysis; Conjunctiva; Diabetes Mellitus - blood; Diabetes Mellitus - therapy; Feasibility Studies; Female; Fluorescence Resonance Energy Transfer - instrumentation; Humans; Implants, Experimental; Male; Middle Aged; Models, Biological; Original; Pilot Projects

To evaluate the feasibility of an implantable subconjunctival glucose monitoring system (SGMS) for glucose monitoring in humans, we investigated the in vivo performance of the sensor in a clinical trial with five patients. The new SGMS consists of an implantable ocular mini implant (OMI) and a hand-...