Quantitative characterization of carotid plaque components using MR apparent diffusion coefficients and longitudinal relaxation rates at 3T: A comparison with histology

• Published in: Journal of magnetic resonance imaging Vol. 48; no. 6; pp. 1657 - 1667
• Main Authors: Ota, Hideki, Tamura, Hajime, Itabashi, Ryo, Yazawa, Yukako, Nakamura, Yasuhiro, Hisamatsu, Kenji, Takamatsu, Manabu, Endo, Hidenori, Niizuma, Kuniyasu, Enomoto, Yukiko, Nagasaka, Tatsuo, Kajita, Kimihiro, Watanabe, Mika, Yoshimura, Shinichi, Yuan, Chun
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.12.2018
• Subjects: Alcohols; apparent diffusion coefficient; carotid plaque components; Classification; Diffusion rate; Field strength; Gadolinium; Hemorrhage; Histology; Ischemia; Lipids; longitudinal relaxation rate; Magnetic resonance imaging; Mathematical analysis; Medical imaging; Plaques; Polyvinyl alcohol; Probability density functions; Statistical analysis; Statistical tests; apparent diffusion coefficient; magnetic resonance imaging; histology; carotid plaque components; longitudinal relaxation rate

Background There is limited evidence of parametric MR mapping to characterize carotid plaques associated with cerebral ischemic events. Purpose To explore the apparent diffusion coefficients (ADCs) and longitudinal relaxation rates (R1) of carotid plaques, including areas of hemorrhage, lipid‐rich/n...