LncRNA CRNDE is downregulated and associated with poor prognostic markers in chronic lymphocytic leukemia

• Published in: International journal of laboratory hematology Vol. 46; no. 1; pp. 107 - 112
• Main Authors: Shehata, Amira M. F., Gohar, Suzy F., Muharram, Nashwa M., Soliman, Shaimaa Sherif, Shalaby, Hadeel M., Kamal Eldin, Samar M., EL‐Bassal, Fathia I.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.02.2024
• Subjects: Chronic lymphocytic leukemia; Down-regulation; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis; Leukemia, Lymphocytic, Chronic, B-Cell - genetics; long noncoding RNA; Non-coding RNA; Prognosis; Reverse transcription; RNA, Long Noncoding - genetics; RT‐qPCR; long noncoding RNA; chronic lymphocytic leukemia; RT-qPCR; prognosis

Introduction Chronic lymphocytic leukemia (CLL) is characterized by a very heterogeneous clinical outcome. Thus, a plethora of prognostic factors and systems has been identified to place patients into different risk categories and to guide therapy decisions. The classic clinical staging models by Ra...