Interleukin 1α and 1β gene variations are associated with tuberculosis in silica exposed subjects

Introduction Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the dev...

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Published inAmerican journal of industrial medicine Vol. 63; no. 1; pp. 74 - 84
Main Authors Salum, Kaio Cezar Rodrigues, Castro, Marcos Cesar Santos, Moreira, Valéria Barbosa, Nani, Angela Santos Ferreira, Kohlrausch, Fabiana Barzotto
Format Journal Article
LanguageEnglish
Published United States Wiley Subscription Services, Inc 01.01.2020
Subjects
Alleles
association study
Brazil
Confidence intervals
Crystal structure
Crystallinity
Cytokines
Exposure
Female
Fibrosis
Gene polymorphism
Genetic Predisposition to Disease
Genetic Variation
genetics
Genotype
Humans
Inflammation
Inhalation
Interleukin 1
Interleukin-1alpha - genetics
Interleukin-1beta - genetics
Interleukins
Lung diseases
Male
Nucleotides
Occupational Exposure
Polymerase chain reaction
Polymorphism
Polymorphism, Single Nucleotide
Respiration
Restriction fragment length polymorphism
Risk Factors
Silica
Silicon dioxide
Silicon Dioxide - toxicity
Silicosis
Silicosis - genetics
Single-nucleotide polymorphism
Tuberculosis
Tuberculosis - genetics
Tumor Necrosis Factor-alpha - genetics
Brazil
silicosis
cytokines
polymorphism
genetics
association study
tuberculosis
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Abstract Introduction Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tuberculosis (Tb). The contribution of inflammatory cytokines to the risk of silicosis and Tb in different populations has previously been reported. Since genetic background might be related to susceptibility to silicosis and Tb, the study of polymorphisms within IL‐1α, IL‐1β, and tumor necrosis factor protein‐coding genes may contribute to elucidating the genetic basis of these diseases. Methods Single nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction using restriction fragment length polymorphism or by Taqman methodology, in a sample of 102 silica‐exposed patients from Brazil. Results No significant associations were observed between the SNPs studied and the severity of silicosis. However, significant associations were found between Tb and the C allele (odds ratio [OR] = 1.93, 95% confidence interval [CI], 1.01‐3.73) and the CC genotype (OR = 2.34, 95% CI, 1.04‐5.31) of IL1A −899C>T. The IL1B +3954C>T polymorphism also showed an association with Tb (T allele dominant model OR = 2.38, 95% CI, 1.04‐5.41). Conclusion These preliminary results demonstrate that the IL1A and IL1B gene variations may contribute to some extent to susceptibility to Tb, but not silicosis. However, additional studies are still needed to confirm these results.
AbstractList IntroductionSilicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tuberculosis (Tb). The contribution of inflammatory cytokines to the risk of silicosis and Tb in different populations has previously been reported. Since genetic background might be related to susceptibility to silicosis and Tb, the study of polymorphisms within IL‐1α, IL‐1β, and tumor necrosis factor protein‐coding genes may contribute to elucidating the genetic basis of these diseases.MethodsSingle nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction using restriction fragment length polymorphism or by Taqman methodology, in a sample of 102 silica‐exposed patients from Brazil.ResultsNo significant associations were observed between the SNPs studied and the severity of silicosis. However, significant associations were found between Tb and the C allele (odds ratio [OR] = 1.93, 95% confidence interval [CI], 1.01‐3.73) and the CC genotype (OR = 2.34, 95% CI, 1.04‐5.31) of IL1A −899C>T. The IL1B +3954C>T polymorphism also showed an association with Tb (T allele dominant model OR = 2.38, 95% CI, 1.04‐5.41).ConclusionThese preliminary results demonstrate that the IL1A and IL1B gene variations may contribute to some extent to susceptibility to Tb, but not silicosis. However, additional studies are still needed to confirm these results.
Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tuberculosis (Tb). The contribution of inflammatory cytokines to the risk of silicosis and Tb in different populations has previously been reported. Since genetic background might be related to susceptibility to silicosis and Tb, the study of polymorphisms within IL-1α, IL-1β, and tumor necrosis factor protein-coding genes may contribute to elucidating the genetic basis of these diseases. Single nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction using restriction fragment length polymorphism or by Taqman methodology, in a sample of 102 silica-exposed patients from Brazil. No significant associations were observed between the SNPs studied and the severity of silicosis. However, significant associations were found between Tb and the C allele (odds ratio [OR] = 1.93, 95% confidence interval [CI], 1.01-3.73) and the CC genotype (OR = 2.34, 95% CI, 1.04-5.31) of IL1A -899C>T. The IL1B +3954C>T polymorphism also showed an association with Tb (T allele dominant model OR = 2.38, 95% CI, 1.04-5.41). These preliminary results demonstrate that the IL1A and IL1B gene variations may contribute to some extent to susceptibility to Tb, but not silicosis. However, additional studies are still needed to confirm these results.
Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tuberculosis (Tb). The contribution of inflammatory cytokines to the risk of silicosis and Tb in different populations has previously been reported. Since genetic background might be related to susceptibility to silicosis and Tb, the study of polymorphisms within IL-1α, IL-1β, and tumor necrosis factor protein-coding genes may contribute to elucidating the genetic basis of these diseases.INTRODUCTIONSilicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tuberculosis (Tb). The contribution of inflammatory cytokines to the risk of silicosis and Tb in different populations has previously been reported. Since genetic background might be related to susceptibility to silicosis and Tb, the study of polymorphisms within IL-1α, IL-1β, and tumor necrosis factor protein-coding genes may contribute to elucidating the genetic basis of these diseases.Single nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction using restriction fragment length polymorphism or by Taqman methodology, in a sample of 102 silica-exposed patients from Brazil.METHODSSingle nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction using restriction fragment length polymorphism or by Taqman methodology, in a sample of 102 silica-exposed patients from Brazil.No significant associations were observed between the SNPs studied and the severity of silicosis. However, significant associations were found between Tb and the C allele (odds ratio [OR] = 1.93, 95% confidence interval [CI], 1.01-3.73) and the CC genotype (OR = 2.34, 95% CI, 1.04-5.31) of IL1A -899C>T. The IL1B +3954C>T polymorphism also showed an association with Tb (T allele dominant model OR = 2.38, 95% CI, 1.04-5.41).RESULTSNo significant associations were observed between the SNPs studied and the severity of silicosis. However, significant associations were found between Tb and the C allele (odds ratio [OR] = 1.93, 95% confidence interval [CI], 1.01-3.73) and the CC genotype (OR = 2.34, 95% CI, 1.04-5.31) of IL1A -899C>T. The IL1B +3954C>T polymorphism also showed an association with Tb (T allele dominant model OR = 2.38, 95% CI, 1.04-5.41).These preliminary results demonstrate that the IL1A and IL1B gene variations may contribute to some extent to susceptibility to Tb, but not silicosis. However, additional studies are still needed to confirm these results.CONCLUSIONThese preliminary results demonstrate that the IL1A and IL1B gene variations may contribute to some extent to susceptibility to Tb, but not silicosis. However, additional studies are still needed to confirm these results.
Introduction Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the International Labour Organization criteria. Furthermore, individuals exposed to crystalline silica also have a higher risk for the development of tuberculosis (Tb). The contribution of inflammatory cytokines to the risk of silicosis and Tb in different populations has previously been reported. Since genetic background might be related to susceptibility to silicosis and Tb, the study of polymorphisms within IL‐1α, IL‐1β, and tumor necrosis factor protein‐coding genes may contribute to elucidating the genetic basis of these diseases. Methods Single nucleotide polymorphisms (SNPs) were genotyped by polymerase chain reaction using restriction fragment length polymorphism or by Taqman methodology, in a sample of 102 silica‐exposed patients from Brazil. Results No significant associations were observed between the SNPs studied and the severity of silicosis. However, significant associations were found between Tb and the C allele (odds ratio [OR] = 1.93, 95% confidence interval [CI], 1.01‐3.73) and the CC genotype (OR = 2.34, 95% CI, 1.04‐5.31) of IL1A −899C>T. The IL1B +3954C>T polymorphism also showed an association with Tb (T allele dominant model OR = 2.38, 95% CI, 1.04‐5.41). Conclusion These preliminary results demonstrate that the IL1A and IL1B gene variations may contribute to some extent to susceptibility to Tb, but not silicosis. However, additional studies are still needed to confirm these results.
Author Nani, Angela Santos Ferreira
Kohlrausch, Fabiana Barzotto
Moreira, Valéria Barbosa
Castro, Marcos Cesar Santos
Salum, Kaio Cezar Rodrigues
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  organization: Universidade Federal Fluminense
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  fullname: Castro, Marcos Cesar Santos
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  fullname: Moreira, Valéria Barbosa
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  fullname: Nani, Angela Santos Ferreira
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  givenname: Fabiana Barzotto
  surname: Kohlrausch
  fullname: Kohlrausch, Fabiana Barzotto
  organization: Universidade Federal Fluminense
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31692000$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1183/09031936.95.08050834
10.4103/0366-6999.198917
10.1183/09031936.94.07030515
10.1007/s00439-008-0497-5
10.1093/aje/kwr159
10.1016/j.pneumo.2015.10.003
10.3390/ijerph15051033
10.1054/tuld.1998.0009
10.1111/jcmm.12341
10.1164/rccm.201412-2150LE
10.1186/ar401
10.1007/s11033-011-1110-x
10.1007/s11033-014-3051-7
10.1016/j.humimm.2016.08.003
10.1002/ajim.20632
10.1007/s40291-015-0130-y
10.1371/journal.pone.0017063
10.1590/S1413-86702009000400002
10.4238/gmr.15017325
10.1177/09680519050110050401
10.1016/S0140-6736(12)60235-9
10.1016/j.ijheh.2006.11.010
10.1111/j.1365-2249.2005.02797.x
10.3892/mmr.2013.1580
10.1016/S2213-2600(17)30387-9
10.1016/j.pupt.2008.04.002
10.1007/s10753-008-9067-1
10.1038/sj.gene.6363766
10.1055/s-0035-1549450
10.1016/j.smim.2014.09.010
10.1590/S1806-37132006000800008
10.1084/jem.189.12.1863
10.1128/IAI.00282-13
10.1007/s00204-013-1063-z
10.1016/j.arbres.2014.07.010
10.1371/journal.pone.0099962
10.1681/ASN.2016020177
10.1016/j.freeradbiomed.2004.05.032
10.1111/sji.12055
10.1164/rccm.201509-1863OC
10.1016/j.vaccine.2010.10.045
10.1038/gene.2014.77
10.1002/eji.200737855
10.1590/S1806-37132008001100012
10.1136/oem.55.7.496
10.3109/08820139.2016.1153650
10.1111/iji.12212
10.1016/j.immuni.2009.02.007
10.1165/rcmb.2009-0211OC
10.1001/jama.1938.02790310022008
10.4084/mjhid.2014.015
10.1016/j.trstmh.2009.03.014
10.1093/hmg/ddx365
10.1016/j.clinbiochem.2014.04.009
10.4238/2015.July.31.8
10.1016/j.gene.2015.07.025
10.1006/taap.2001.9124
10.1182/blood-2010-07-273417
10.1371/journal.pone.0147005
10.1111/j.1399-0039.2006.00566.x
10.1164/ajrccm.165.4.2106009
10.1054/tube.2001.0307
10.1289/ehp.99107s5793
10.1539/joh.L8006
10.1046/j.1365-2249.2003.02171.x
10.1002/1529-0131(200110)44:10<2296::AID-ART392>3.0.CO;2-9
10.2217/pgs-2016-0085
10.1002/1097-0274(200103)39:3<286::AID-AJIM1016>3.0.CO;2-7
10.1128/IAI.00443-12
10.1016/j.rcl.2016.05.015
10.1016/j.cyto.2012.06.006
10.1016/j.archoralbio.2015.06.018
10.4049/jimmunol.175.8.5333
10.1097/AJP.0000000000000048
10.1007/s11033-014-3741-1
10.1038/s41467-017-00257-5
10.1016/j.tube.2005.03.001
10.1016/j.biomaterials.2011.12.008
10.1371/journal.ppat.1004426
10.1038/sj.gene.6364133
10.1089/dna.2018.4370
10.1183/09031936.06.00132505
10.1111/j.1440-1843.2007.01108.x
10.1164/ajrccm.157.5.9707141
10.3892/ijmm.2012.996
10.3923/pjbs.2014.419.423
10.1038/ng.2609
10.1016/j.etp.2009.11.006
10.1186/1471-2350-15-8
10.1056/NEJMc071324
10.1016/j.smim.2014.09.004
10.1111/2049-632X.12075
10.1086/344891
10.1590/S1415-47572014000200003
10.1016/1043-4666(93)90024-Y
10.1371/journal.pone.0140952
10.1080/08958370050164842
10.1007/s00251-002-0445-9
10.1186/s12989-014-0069-x
10.1111/eci.12702
10.1183/09031936.00075107
10.1016/j.gene.2018.03.098
10.1016/j.cyto.2011.09.021
10.1164/ajrccm.165.5.2010050
10.1016/j.smim.2014.09.011
10.1016/S0140-6736(96)07336-9
10.2471/BLT.15.163550
10.1002/ajim.20616
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Keywords silicosis
cytokines
polymorphism
genetics
association study
tuberculosis
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References 2005; 175
2011; 117
2006; 32
2008; 38
2014; 26
2008; 34
2004; 5
2011; 56
2008; 31
2001; 44
2013; 8
1998; 157
1976; 113
2009; 13
2000; 12
2004; 37
2006; 28
2007; 210
2011; 63
2014; 15
2008; 21
2014; 18
2014; 17
2012; 25
2012; 379
2014; 11
2018; 37
2014; 10
2016; 45
2013; 87
2015; 51
2014; 47
2002; 4
2016; 94
2017; 130
2012; 39
1999; 189
2014; 41
2008; 123
2008; 50
2008; 51
2016; 17
1999; 107
2011; 6
2012; 33
2016; 15
2007; 12
2012; 30
1995; 8
2016; 11
2010; 43
2015; 191
2015; 60
2013; 78
2014; 37
2013; 81
2001; 39
2016; 27
2009; 103
2005; 11
2018; 15
1998; 79
2017; 5
2012; 60
2015; 36
2017; 8
2014; 70
2017; 47
2013; 23
2002; 54
2008; 8
2016; 72
1993; 5
2016; 77
2001; 172
1997; 349
2005; 140
2006; 67
2002; 186
2015; 42
2002; 46
1943; 47
2015; 573
2005; 32
2014; 9
2016; 193
2011; 29
2014; 6
1998; 55
2018; 661
2015; 14
2012; 80
2015; 16
2015; 19
1938; 111
2017; 26
2013; 45
2006; 17
2015; 10
2016; 54
2007
2011; 174
1978; 117
2003; 133
2007; 357
2001; 81
2009; 30
2006; 86
2002; 165
2013; 30
2001; 2
2012; 7
2012; 4
1994; 7
Amirzargar AA (e_1_2_10_31_1) 2006; 17
e_1_2_10_21_1
e_1_2_10_44_1
e_1_2_10_40_1
e_1_2_10_109_1
Comstock GW (e_1_2_10_26_1) 1978; 117
Wang YW (e_1_2_10_63_1) 2012; 25
e_1_2_10_70_1
e_1_2_10_93_1
e_1_2_10_2_1
Nasiri R (e_1_2_10_56_1) 2013; 23
e_1_2_10_18_1
e_1_2_10_74_1
e_1_2_10_97_1
e_1_2_10_116_1
e_1_2_10_6_1
e_1_2_10_55_1
e_1_2_10_14_1
e_1_2_10_37_1
e_1_2_10_78_1
e_1_2_10_112_1
e_1_2_10_13_1
e_1_2_10_32_1
e_1_2_10_51_1
World Health Organization (e_1_2_10_3_1) 2007
e_1_2_10_120_1
e_1_2_10_82_1
e_1_2_10_29_1
e_1_2_10_86_1
e_1_2_10_105_1
e_1_2_10_48_1
e_1_2_10_67_1
e_1_2_10_101_1
e_1_2_10_45_1
e_1_2_10_22_1
e_1_2_10_41_1
e_1_2_10_90_1
e_1_2_10_71_1
e_1_2_10_117_1
e_1_2_10_94_1
e_1_2_10_52_1
e_1_2_10_19_1
e_1_2_10_75_1
e_1_2_10_113_1
e_1_2_10_38_1
e_1_2_10_98_1
e_1_2_10_79_1
e_1_2_10_15_1
e_1_2_10_10_1
e_1_2_10_33_1
Kallmann FJ (e_1_2_10_25_1) 1943; 47
Zhou Y (e_1_2_10_64_1) 2008; 8
e_1_2_10_121_1
e_1_2_10_60_1
e_1_2_10_106_1
e_1_2_10_102_1
e_1_2_10_49_1
e_1_2_10_87_1
e_1_2_10_68_1
e_1_2_10_23_1
e_1_2_10_46_1
e_1_2_10_69_1
e_1_2_10_42_1
e_1_2_10_110_1
e_1_2_10_91_1
e_1_2_10_72_1
e_1_2_10_95_1
e_1_2_10_118_1
e_1_2_10_53_1
e_1_2_10_16_1
e_1_2_10_39_1
e_1_2_10_76_1
e_1_2_10_99_1
e_1_2_10_114_1
e_1_2_10_8_1
e_1_2_10_57_1
e_1_2_10_58_1
e_1_2_10_34_1
e_1_2_10_11_1
e_1_2_10_30_1
e_1_2_10_119_1
Lopes‐Pacheco M (e_1_2_10_7_1) 2012; 4
e_1_2_10_80_1
e_1_2_10_61_1
e_1_2_10_84_1
e_1_2_10_107_1
e_1_2_10_27_1
e_1_2_10_65_1
e_1_2_10_88_1
e_1_2_10_103_1
e_1_2_10_43_1
e_1_2_10_20_1
e_1_2_10_108_1
McCanlies E (e_1_2_10_24_1) 2002; 46
Correa PA (e_1_2_10_111_1) 2005; 32
e_1_2_10_92_1
e_1_2_10_73_1
e_1_2_10_115_1
e_1_2_10_96_1
e_1_2_10_54_1
e_1_2_10_5_1
e_1_2_10_17_1
e_1_2_10_77_1
e_1_2_10_36_1
e_1_2_10_12_1
e_1_2_10_35_1
Rad IA (e_1_2_10_85_1) 2012; 7
e_1_2_10_9_1
e_1_2_10_59_1
e_1_2_10_50_1
Vanhee D (e_1_2_10_83_1) 1995; 8
e_1_2_10_81_1
e_1_2_10_62_1
Ziskind M (e_1_2_10_4_1) 1976; 113
e_1_2_10_104_1
e_1_2_10_28_1
e_1_2_10_66_1
e_1_2_10_100_1
e_1_2_10_47_1
e_1_2_10_89_1
References_xml – volume: 8
  start-page: 599
  issue: 1
  year: 2017
  article-title: Genome‐wide association and HLA region fine‐mapping studies identify susceptibility loci for multiple common infections
  publication-title: Nat Commun
– volume: 78
  start-page: 92
  year: 2013
  end-page: 97
  article-title: Association of IL‐1β +3954 C/T and IL‐10‐1082 G/A cytokine gene polymorphisms with susceptibility to tuberculosis
  publication-title: Scand J Immunol
– volume: 34
  start-page: 959
  year: 2008
  end-page: 966
  article-title: Tuberculose e silicose: epidemiologia, diagnóstico e quimioprofilaxia
  publication-title: J Bras Pneumol
– volume: 54
  start-page: 82
  issue: 2
  year: 2002
  end-page: 86
  article-title: Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin‐1α
  publication-title: Immunogenetics
– volume: 63
  start-page: 175
  year: 2011
  end-page: 179
  article-title: Possible effect of gene polymorphisms on the release of TNFalpha and IL1 cytokines in coal workers’ pneumoconiosis
  publication-title: Exp Toxicol Pathol
– volume: 379
  start-page: 2008
  year: 2012
  end-page: 2018
  article-title: Silicosis
  publication-title: Lancet
– volume: 32
  start-page: S41
  year: 2006
  end-page: S47
  article-title: Silicose
  publication-title: J Bras Pneumol
– volume: 130
  start-page: 357
  year: 2017
  end-page: 364
  article-title: Association between genetic variants of transforming growth factor‐β1 and susceptibility of pneumoconiosis: a meta‐analysis
  publication-title: Chin Med J (Engl)
– volume: 43
  start-page: 465
  year: 2010
  end-page: 474
  article-title: STAT3, p38 MAPK, and NF‐κB drive unopposed monocyte‐dependent fibroblast MMP‐1 secretion in tuberculosis
  publication-title: Am J Respir Cell Mol Biol
– volume: 16
  start-page: 127
  issue: 2
  year: 2015
  end-page: 133
  article-title: Polymorphisms in TICAM2 and IL1B are associated with TB
  publication-title: Genes Immun
– volume: 17
  start-page: 84
  year: 2006
  end-page: 89
  article-title: Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis
  publication-title: Eur Cytokine Netw
– volume: 33
  start-page: 2399
  year: 2012
  end-page: 2407
  article-title: Pathological mechanisms of liver injury caused by continuous intraperitoneal injection of silica nanoparticles
  publication-title: Biomaterials
– volume: 8
  start-page: 741
  year: 2013
  end-page: 746
  article-title: Therapeutic effect of exogenous bone marrow‐derived mesenchymal stem cell transplantation on silicosis via paracrine mechanisms in rats
  publication-title: Mol Med Rep
– volume: 25
  start-page: 517
  year: 2012
  end-page: 525
  article-title: TNF‐alpha and IL‐1RA polymorphisms and silicosis susceptibility in Chinese workers exposed to silica particles: a case‐control study
  publication-title: Biomed Environ Sci
– volume: 21
  start-page: 675
  year: 2008
  end-page: 681
  article-title: Interleukin‐1beta up‐regulates tumor necrosis factor receptors in the mouse airways
  publication-title: Pulm Pharmacol Ther
– volume: 4
  start-page: 36
  year: 2012
  end-page: 43
  article-title: Silicose: Mecanismos De Atuação Da Partícula De Sílica No Tecido Pulmonar
  publication-title: Interdiscip J Exp Stud
– volume: 117
  start-page: 621
  issue: 4
  year: 1978
  end-page: 624
  article-title: Tuberculosis in twins: a re‐analysis of the Prophit survey
  publication-title: Am Rev Respir Dis
– volume: 31
  start-page: 215
  year: 2008
  end-page: 221
  article-title: Hepatoprotective effect of infliximab, an anti‐TNF‐α agent, on carbon tetrachloride‐induced hepatic fibrosis
  publication-title: Inflammation
– volume: 56
  start-page: 550
  year: 2011
  end-page: 559
  article-title: A meta‐analysis of tumor necrosis factor‐alpha, interleukin‐6, and interleukin‐10 in preeclampsia
  publication-title: Cytokine
– volume: 4
  start-page: 157
  year: 2002
  end-page: 164
  article-title: Transcriptional regulation of collagenase (MMP‐1, MMP‐13) genes in arthritis: Integration of complex signaling pathways for the recruitment of gene‐specific transcription factors
  publication-title: Arthritis Res
– volume: 41
  start-page: 2029
  year: 2014
  end-page: 2036
  article-title: Association between TNF promoter ‐308 G>A and LTA 252 A>G polymorphisms and systemic lupus erythematosus
  publication-title: Mol Biol Rep
– volume: 55
  start-page: 496
  year: 1998
  end-page: 502
  article-title: Risk of pulmonary tuberculosis relative to silicosis and exposure to silica dust in South African gold miners
  publication-title: Occup Environ Med
– volume: 8
  start-page: 834
  year: 1995
  end-page: 842
  article-title: Cytokines and cytokine network in silicosis and coal workers’ pneumoconiosis
  publication-title: Eur Respir J
– volume: 17
  start-page: 419
  year: 2014
  end-page: 423
  article-title: Silicosis and its progress influenced by genetic variation on TNF‐α locus‐ 308, TNF‐α and IL‐10 cytokine on cement factory workers in Indonesia
  publication-title: Pakistan J Biol Sci
– volume: 80
  start-page: 3343
  year: 2012
  end-page: 3359
  article-title: Innate immune gene polymorphisms in tuberculosis
  publication-title: Infect Immun
– volume: 174
  start-page: 839
  year: 2011
  end-page: 848
  article-title: Silicosis mortality with respiratory tuberculosis in the united states, 1968‐2006
  publication-title: Am J Epidemiol
– volume: 39
  start-page: 286
  year: 2001
  end-page: 291
  article-title: Polymorphisms of the IL‐1 gene complex in coal miners with silicosis
  publication-title: Am J Ind Med
– volume: 86
  start-page: 11
  year: 2006
  end-page: 19
  article-title: Cytokine gene polymorphisms in Colombian patients with different clinical presentations of tuberculosis
  publication-title: Tuberculosis
– volume: 15
  start-page: 1
  year: 2016
  end-page: 8
  article-title: Association between IL‐1α rs17561 and IL‐1β rs1143634 polymorphisms and periodontitis: a meta‐analysis
  publication-title: Genet Mol Res
– volume: 19
  start-page: 53
  year: 2015
  end-page: 57
  article-title: TNF‐α −308 G/A as a risk marker of cervical cancer progression in the Polish population
  publication-title: Mol Diagnosis Ther.
– volume: 186
  start-page: 1463
  year: 2002
  end-page: 1468
  article-title: Ethnic‐specific genetic associations with pulmonary tuberculosis
  publication-title: J Infect Dis
– volume: 157
  start-page: 1666
  year: 1998
  end-page: 1680
  article-title: Mechanisms in the pathogenesis of asbestosis and silicosis
  publication-title: Am J Respir Crit Care Med
– volume: 13
  start-page: 252
  year: 2009
  end-page: 256
  article-title: The NRAMPI, VDR and TNF‐alpha gene polymorphisms in Iranian tuberculosis patients: the study on host susceptibility
  publication-title: Braz J Infect Dis
– volume: 15
  issue: 5
  year: 2018
  article-title: Tobacco smoke induces and alters immune responses in the lung triggering inflammation, allergy, asthma and other lung diseases: a mechanistic review
  publication-title: Int J Environ Res Public Health
– volume: 133
  start-page: 30
  issue: 1
  year: 2003
  end-page: 37
  article-title: A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes
  publication-title: Clin Exp Immunol
– volume: 30
  start-page: 576
  issue: 4
  year: 2009
  end-page: 587
  article-title: Critical regulation of early Th17 cell differentiation by interleukin‐1 signaling
  publication-title: Immunity
– volume: 2
  start-page: 222
  year: 2001
  end-page: 228
  article-title: IL‐1B and IL‐1Ra gene polymorphisms and disease severity in rheumatoid arthritis: interaction with their plasma levels
  publication-title: Genes Immun
– volume: 191
  start-page: 596
  year: 2015
  end-page: 598
  article-title: Treating pulmonary silicosis by blocking interleukin 1
  publication-title: Am J Respir Crit Care Med
– volume: 67
  start-page: 290
  year: 2006
  end-page: 296
  article-title: Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis
  publication-title: Tissue Antigens
– volume: 42
  start-page: 71
  year: 2015
  end-page: 76
  article-title: Gene polymorphisms in patients with pulmonary tuberculosis from Mozambique
  publication-title: Mol Biol Rep
– volume: 45
  start-page: 613
  year: 2013
  end-page: 620
  article-title: Genome‐wide association study identifies multiple susceptibility loci for pulmonary fibrosis
  publication-title: Nat Genet
– volume: 70
  start-page: 51
  year: 2014
  end-page: 60
  article-title: The RD1 locus in the Mycobacterium tuberculosis genome contributes to the maturation and secretion of IL‐1α from infected macrophages through the elevation of cytoplasmic calcium levels and calpain activation
  publication-title: Pathog Dis
– volume: 47
  start-page: 1209
  year: 2014
  end-page: 1213
  article-title: Interleukin‐1β genotype and circulating levels in cancer patients: metastatic status and pain perception
  publication-title: Clin Biochem
– volume: 6
  issue: 2
  year: 2011
  article-title: The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected
  publication-title: PLoS One
– volume: 26
  start-page: 471
  year: 2014
  end-page: 485
  article-title: Macrophage immunoregulatory pathways in tuberculosis
  publication-title: Semin Immunol
– volume: 189
  start-page: 1863
  issue: 12
  year: 1999
  end-page: 1874
  article-title: Influence of polymorphism in the genes for the interleukin (IL)‐1 receptor antagonist and IL‐1b on tuberculosis
  publication-title: J Exp Med
– year: 2007
– volume: 45
  start-page: 284
  year: 2016
  end-page: 297
  article-title: Association of and gene variants with autoimmune thyroid diseases in Tunisian population
  publication-title: Immunol Invest
– volume: 29
  start-page: 1339
  year: 2011
  end-page: 1346
  article-title: Blocking IL‐1α but not IL‐1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice
  publication-title: Vaccine
– volume: 50
  start-page: 445
  year: 2008
  end-page: 454
  article-title: Lack of association between cytokine gene polymorphisms and silicosis and pulmonary tuberculosis in Chinese iron miners
  publication-title: J Occup Health
– volume: 23
  start-page: 455
  year: 2013
  end-page: 461
  article-title: Single‐nucleotide polymorphisms of TNFA and IL1 in allergic rhinitis
  publication-title: J Investig Allergol Clin Immunol
– volume: 175
  start-page: 5333
  year: 2005
  end-page: 5340
  article-title: Mycobacterium tuberculosis up‐regulates matrix metalloproteinase‐1 secretion from human airway epithelial cells via a p38 MAPK switch
  publication-title: J Immunol
– volume: 9
  issue: 6
  year: 2014
  article-title: Association between tumor necrosis factor‐α rs1800629 polymorphism and risk of asthma: A meta‐analysis
  publication-title: PLoS One
– volume: 5
  start-page: 609
  year: 2004
  end-page: 614
  article-title: Interleukin‐1beta polymorphisms in Colombian patients with autoimmune rheumatic diseases
  publication-title: Genes Immun
– volume: 26
  start-page: 4752
  year: 2017
  end-page: 4763
  article-title: Discovery of susceptibility loci associated with tuberculosis in Han Chinese
  publication-title: Hum Mol Genet
– volume: 81
  start-page: 3750
  year: 2013
  end-page: 3756
  article-title: Low induction of proinflammatory cytokines parallels evolutionary success of modern strains within the mycobacterium tuberculosis beijing genotype
  publication-title: Infect Immun
– volume: 10
  year: 2015
  article-title: Effects of the interactions between dust exposure and genetic polymorphisms in Nalp3, Caspase‐1, and IL‐1beta on the risk of silicosis: a case‐control study
  publication-title: PLoS One
– volume: 47
  start-page: 549
  issue: 6
  year: 1943
  end-page: 574
  article-title: Twin studies on the significance of genetic factors in tuberculosis
  publication-title: Am Rev Tuberc Pulm Dis
– volume: 17
  start-page: 1999
  year: 2016
  end-page: 2006
  article-title: rs1800587 associates with chronic noncrisis pain in sickle cell disease
  publication-title: Pharmacogenomics
– volume: 11
  start-page: 281
  year: 2005
  end-page: 286
  article-title: Polymorphism in IL1B: IL1B‐511 association with tuberculosis and decreased lipopolysaccharide‐induced IL‐1beta in IFN‐gamma primed ex‐vivo whole blood assay
  publication-title: J Endotoxin Res
– volume: 87
  start-page: 1963
  year: 2013
  end-page: 1973
  article-title: Neutralization of interleukin‐1 beta attenuates silica‐induced lung inflammation and fibrosis in C57BL/6 mice
  publication-title: Arch Toxicol
– volume: 349
  start-page: 1311
  year: 1997
  end-page: 1315
  article-title: Asbestosis and silicosis
  publication-title: Lancet
– volume: 27
  start-page: 2564
  year: 2016
  end-page: 2575
  article-title: Of inflammasomes and alarmins: IL‐1 and IL‐1 in kidney disease
  publication-title: J Am Soc Nephrol
– volume: 12
  start-page: 7
  year: 2000
  end-page: 14
  article-title: From coal mine dust to quartz: mechanisms of pulmonary pathogenicity
  publication-title: Inhal Toxicol
– volume: 37
  start-page: 916
  year: 2004
  end-page: 925
  article-title: Signaling pathways controlling the production of inflammatory mediators in response to crystalline silica exposure: role of reactive oxygen/nitrogen species
  publication-title: Free Radic Biol Med
– volume: 165
  start-page: 690
  year: 2002
  end-page: 693
  article-title: Polymorphisms in the tumor necrosis factor‐alpha gene promoter may predispose to severe silicosis in black South African miners
  publication-title: Am J Respir Crit Care Med
– volume: 14
  start-page: 8602
  year: 2015
  end-page: 8612
  article-title: Associations between tumor necrosis factor‐α polymorphisms and susceptibility to pulmonary tuberculosis: meta‐analysis
  publication-title: Genet Mol Res
– volume: 42
  start-page: 423
  year: 2015
  end-page: 427
  article-title: IL‐1A rs1800587, IL‐1B rs1143634 and IL‐1R1 rs2234650 polymorphisms in Iranian patients with systemic sclerosis
  publication-title: Int J Immunogenet
– volume: 94
  start-page: 777
  year: 2016
  end-page: 778
  article-title: Silicosis and silicotuberculosis in India
  publication-title: Bull World Health Organ
– volume: 26
  start-page: 543
  year: 2014
  end-page: 551
  article-title: Pro‐and anti‐inflammatory cytokines in tuberculosis: a two‐edged sword in TB pathogenesis
  publication-title: Semin Immunol
– volume: 28
  start-page: 1013
  year: 2006
  end-page: 1019
  article-title: Genetic linkage analysis of pulmonary fibrotic response to silica in mice
  publication-title: Eur Respir J
– volume: 51
  start-page: 741
  year: 2008
  end-page: 747
  article-title: Association of cytokine gene polymorphisms in CWP and its severity in Turkish coal workers
  publication-title: Am J Ind Med
– volume: 193
  start-page: 1151
  year: 2016
  end-page: 1160
  article-title: Desmoplakin variants are associated with idiopathic pulmonary fibrosis
  publication-title: Am J Respir Crit Care Med
– volume: 36
  start-page: 347
  issue: 3
  year: 2015
  end-page: 357
  article-title: Gene‐environment interaction from international cohorts: impact on development and evolution of occupational and environmental lung and airway disease
  publication-title: Semin Respir Crit Care Med
– volume: 140
  start-page: 443
  year: 2005
  end-page: 449
  article-title: Differential pattern of cytokine expression by macrophages infected in vitro with different Mycobacterium tuberculosis genotypes
  publication-title: Clin Exp Immunol
– volume: 107
  start-page: 793
  year: 1999
  end-page: 802
  article-title: Occupational exposure to crystalline silica and autoimmune disease
  publication-title: Environ Health Perspect
– volume: 10
  issue: 10
  year: 2014
  article-title: Allele‐specific induction of IL‐1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibility
  publication-title: PLoS Pathog
– volume: 46
  start-page: 375
  year: 2002
  end-page: 381
  article-title: Significance of genetic information in risk assessment and individual classification using silicosis as a case model
  publication-title: Ann Occup Hyg
– volume: 15
  start-page: 8
  year: 2014
  article-title: Associations between interleukin‐1 gene polymorphisms and sepsis risk: a meta‐analysis
  publication-title: BMC Med Genet
– volume: 210
  start-page: 679
  year: 2007
  end-page: 689
  article-title: Genetic polymorphisms in alveolar macrophage response‐related genes, and risk of silicosis and pulmonary tuberculosis in Chinese iron miners
  publication-title: Int J Hyg Environ Health
– volume: 18
  start-page: 1773
  year: 2014
  end-page: 1784
  article-title: Th17 can regulate silica‐induced lung inflammation through an IL‐1β‐dependent mechanism
  publication-title: J Cell Mol Med
– volume: 60
  start-page: 1463
  year: 2015
  end-page: 1470
  article-title: Association analysis of the IL‐1 gene cluster polymorphisms with aggressive and chronic periodontitis in the Algerian population
  publication-title: Arch Oral Biol
– volume: 103
  start-page: 581
  year: 2009
  end-page: 587
  article-title: Reduced TNF‐α and IFN‐γ responses to Central Asian strain 1 and Beijing isolates of Mycobacterium tuberculosis in comparison with H37Rv strain
  publication-title: Trans R Soc Trop Med Hyg
– volume: 72
  start-page: 179
  year: 2016
  end-page: 183
  article-title: La silicotuberculose
  publication-title: Rev Pneumol Clin
– volume: 60
  start-page: 76
  year: 2012
  end-page: 82
  article-title: Analysis of IL1 gene polymorphisms and transcript levels in periodontal and chronic kidney disease
  publication-title: Cytokine
– volume: 30
  start-page: 869
  year: 2013
  end-page: 874
  article-title: The interleukin‐1 alpha gene C>T polymorphism rs1,800,587 is associated with increased pain intensity and decreased pressure pain thresholds in patients with lumbar radicular pain
  publication-title: Clin J Pain
– volume: 38
  start-page: 1321
  year: 2008
  end-page: 1330
  article-title: Monocyte‐dependent oncostatin M and TNF‐α synergize to stimulate unopposed matrix metalloproteinase‐1/3 secretion from human lung fibroblasts in tuberculosis
  publication-title: Eur J Immunol
– volume: 79
  start-page: 83
  year: 1998
  end-page: 89
  article-title: Assessment of the interleukin 1 gene cluster and other candidate gene polymorphisms in host susceptibility to tuberculosis
  publication-title: Tuber Lung Dis
– volume: 117
  start-page: 3720
  year: 2011
  end-page: 3732
  article-title: Interleukin‐1 in the pathogenesis and treatment of inflammatory diseases
  publication-title: Blood
– volume: 32
  start-page: 219
  year: 2005
  end-page: 224
  article-title: Autoimmunity and tuberculosis. Opposite association with TNF polymorphism
  publication-title: J Rheumatol
– volume: 573
  start-page: 75
  issue: 1
  year: 2015
  end-page: 83
  article-title: IL‐1 β +3953C/T, −511T/C and IL‐6 −174C/G polymorphisms in association with tuberculosis susceptibility: A meta‐analysis
  publication-title: Gene
– volume: 8
  start-page: 641
  year: 2008
  end-page: 648
  article-title: Polymorphisms in long noncoding RNA H19 contribute to the protective effects of coal workers’ pneumoconiosis in a Chinese population
  publication-title: PLoS One
– volume: 661
  start-page: 196
  year: 2018
  end-page: 201
  article-title: The rs2609255 polymorphism in the FAM13A gene is reproducibly associated with silicosis susceptibility in a Chinese population
  publication-title: Gene
– volume: 123
  start-page: 477
  year: 2008
  end-page: 484
  article-title: IFNG +874T/A, IL10 ‐1082G/A and TNF ‐308G/A polymorphisms in association with tuberculosis susceptibility: A meta‐analysis study
  publication-title: Hum Genet
– volume: 30
  start-page: 401
  year: 2012
  end-page: 408
  article-title: Interleukin gene polymorphisms in pneumoconiosis
  publication-title: Int J Mol Med
– volume: 44
  start-page: 2296
  year: 2001
  end-page: 2310
  article-title: Synergistic induction of matrix metalloproteinase 1 by interleukin‐1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism
  publication-title: Arthritis Rheum
– volume: 11
  start-page: 69
  year: 2014
  article-title: The alarmin IL‐1α is a master cytokine in acute lung inflammation induced by silica micro‐ and nanoparticles
  publication-title: Part Fibre Toxicol
– volume: 165
  start-page: 527
  year: 2002
  end-page: 533
  article-title: Crucial role of interleukin‐1beta and nitric oxide synthase in silica‐induced inflammation and apoptosis in mice
  publication-title: Am J Respir Crit Care Med
– volume: 39
  start-page: 3393
  year: 2012
  end-page: 3400
  article-title: TNF‐308 gene polymorphism and tuberculosis susceptibility: a meta‐analysis involving 18 studies
  publication-title: Mol Biol Rep
– volume: 31
  start-page: 1177
  year: 2008
  end-page: 1182
  article-title: Genetic susceptibility to progressive massive fibrosis in coal miners
  publication-title: Eur Respir J
– volume: 26
  start-page: 552
  year: 2014
  end-page: 558
  article-title: Chemokines in tuberculosis: the good, the bad and the ugly
  publication-title: Semin Immunol
– volume: 7
  start-page: 20
  year: 2012
  end-page: 24
  article-title: Molecular evaluation of the IFN γ +874, TNF α ‐308, and IL‐1Ra VNTR sequences in silicosis
  publication-title: Mædica
– volume: 6
  issue: 1
  year: 2014
  article-title: Association of mycobacterium tuberculosis lineages with IFN‐γ and TNF‐α gene polymorphisms among pulmonary tuberculosis patient
  publication-title: Mediterr J Hematol Infect Dis
– volume: 12
  start-page: 594
  year: 2007
  end-page: 598
  article-title: Polymorphisms of interleukin‐10 and tumour necrosis factor‐a genes are associated with newly diagnosed and recurrent pulmonary tuberculosis
  publication-title: Respirology
– volume: 54
  start-page: 1077
  year: 2016
  end-page: 1096
  article-title: Imaging of occupational lung disease
  publication-title: Radiol Clin North Am
– volume: 5
  start-page: 57
  year: 1993
  end-page: 61
  article-title: Interleukin 1 receptor antagonist (IL‐1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica
  publication-title: Cytokine
– volume: 77
  start-page: 1275
  year: 2016
  end-page: 1279
  article-title: Association of IL‐1β +3953 C and HLA‐DRB1*15 with coronary artery and rheumatic heart diseases in South India
  publication-title: Hum Immunol
– volume: 37
  start-page: 151
  year: 2014
  end-page: 170
  article-title: Interethnic admixture and the evolution of Latin American populations
  publication-title: Genet Mol Biol
– volume: 47
  start-page: 53
  year: 2017
  end-page: 62
  article-title: IL‐1B rs16944 polymorphism is related to septic shock and death
  publication-title: Eur J Clin Invest
– volume: 51
  start-page: 843
  year: 2008
  end-page: 851
  article-title: Genetic polymorphisms of IL‐1A, IL‐1B, IL‐1RN, NFKB1, FAS, and FASL, and risk of silicosis in a Chinese occupational population
  publication-title: Am J Ind Med
– volume: 357
  start-page: 302
  year: 2007
  end-page: 303
  article-title: Interleukin‐1‐receptor antagonist in type 2 diabetes mellitus
  publication-title: N Engl J Med
– volume: 5
  start-page: 869
  year: 2017
  end-page: 880
  article-title: Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome‐wide association study
  publication-title: Lancet Respir Med
– volume: 111
  start-page: 400
  issue: 5
  year: 1938
  end-page: 408
  article-title: Silicosis and silicotuberculosis
  publication-title: J Am Med Assoc
– volume: 81
  start-page: 335
  year: 2001
  end-page: 341
  article-title: Tumour necrosis factor alpha (‐238 and ‐308) and beta gene polymorphisms in pulmonary tuberculosis: haplotype analysis with HLA‐A, B and DR genes
  publication-title: Tuberculosis
– volume: 51
  start-page: 86
  year: 2015
  end-page: 93
  article-title: Normativa para el diagnóstico y seguimiento de la silicosis
  publication-title: Arch Bronconeumol
– volume: 7
  start-page: 515
  year: 1994
  end-page: 518
  article-title: Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice
  publication-title: Eur Respir J
– volume: 11
  start-page: 1
  year: 2016
  end-page: 17
  article-title: Dasatinib reduces lung inflammation and fibrosis in acute experimental silicosis
  publication-title: PLoS One
– volume: 37
  start-page: 925
  year: 2018
  end-page: 931
  article-title: A novel variant of desmoplakin is potentially associated with silicosis risk
  publication-title: DNA Cell Biol
– volume: 113
  start-page: 643
  year: 1976
  end-page: 665
  article-title: Silicosis
  publication-title: Am Rev Respir Dis
– volume: 172
  start-page: 75
  year: 2001
  end-page: 82
  article-title: Association of tumor necrosis factor‐alpha and interleukin‐1 gene polymorphisms with silicosis
  publication-title: Toxicol Appl Pharmacol
– volume: 8
  start-page: 834
  year: 1995
  ident: e_1_2_10_83_1
  article-title: Cytokines and cytokine network in silicosis and coal workers’ pneumoconiosis
  publication-title: Eur Respir J
  doi: 10.1183/09031936.95.08050834
– ident: e_1_2_10_19_1
  doi: 10.4103/0366-6999.198917
– volume: 17
  start-page: 84
  year: 2006
  ident: e_1_2_10_31_1
  article-title: Cytokine single nucleotide polymorphisms in Iranian patients with pulmonary tuberculosis
  publication-title: Eur Cytokine Netw
– ident: e_1_2_10_35_1
  doi: 10.1183/09031936.94.07030515
– ident: e_1_2_10_65_1
  doi: 10.1007/s00439-008-0497-5
– ident: e_1_2_10_15_1
  doi: 10.1093/aje/kwr159
– ident: e_1_2_10_12_1
  doi: 10.1016/j.pneumo.2015.10.003
– volume: 25
  start-page: 517
  year: 2012
  ident: e_1_2_10_63_1
  article-title: TNF‐alpha and IL‐1RA polymorphisms and silicosis susceptibility in Chinese workers exposed to silica particles: a case‐control study
  publication-title: Biomed Environ Sci
– ident: e_1_2_10_67_1
  doi: 10.3390/ijerph15051033
– ident: e_1_2_10_98_1
  doi: 10.1054/tuld.1998.0009
– ident: e_1_2_10_33_1
  doi: 10.1111/jcmm.12341
– ident: e_1_2_10_76_1
  doi: 10.1164/rccm.201412-2150LE
– ident: e_1_2_10_96_1
  doi: 10.1186/ar401
– ident: e_1_2_10_117_1
  doi: 10.1007/s11033-011-1110-x
– ident: e_1_2_10_59_1
  doi: 10.1007/s11033-014-3051-7
– ident: e_1_2_10_73_1
  doi: 10.1016/j.humimm.2016.08.003
– ident: e_1_2_10_44_1
  doi: 10.1002/ajim.20632
– ident: e_1_2_10_61_1
  doi: 10.1007/s40291-015-0130-y
– ident: e_1_2_10_121_1
  doi: 10.1371/journal.pone.0017063
– volume: 46
  start-page: 375
  year: 2002
  ident: e_1_2_10_24_1
  article-title: Significance of genetic information in risk assessment and individual classification using silicosis as a case model
  publication-title: Ann Occup Hyg
– ident: e_1_2_10_115_1
  doi: 10.1590/S1413-86702009000400002
– ident: e_1_2_10_52_1
  doi: 10.4238/gmr.15017325
– ident: e_1_2_10_104_1
  doi: 10.1177/09680519050110050401
– ident: e_1_2_10_2_1
  doi: 10.1016/S0140-6736(12)60235-9
– ident: e_1_2_10_87_1
  doi: 10.1016/j.ijheh.2006.11.010
– ident: e_1_2_10_108_1
  doi: 10.1111/j.1365-2249.2005.02797.x
– ident: e_1_2_10_36_1
  doi: 10.3892/mmr.2013.1580
– ident: e_1_2_10_89_1
  doi: 10.1016/S2213-2600(17)30387-9
– ident: e_1_2_10_70_1
  doi: 10.1016/j.pupt.2008.04.002
– ident: e_1_2_10_81_1
  doi: 10.1007/s10753-008-9067-1
– ident: e_1_2_10_53_1
  doi: 10.1038/sj.gene.6363766
– ident: e_1_2_10_23_1
  doi: 10.1055/s-0035-1549450
– ident: e_1_2_10_97_1
  doi: 10.1016/j.smim.2014.09.010
– ident: e_1_2_10_8_1
  doi: 10.1590/S1806-37132006000800008
– ident: e_1_2_10_102_1
  doi: 10.1084/jem.189.12.1863
– ident: e_1_2_10_22_1
  doi: 10.1128/IAI.00282-13
– ident: e_1_2_10_32_1
  doi: 10.1007/s00204-013-1063-z
– ident: e_1_2_10_11_1
  doi: 10.1016/j.arbres.2014.07.010
– ident: e_1_2_10_60_1
  doi: 10.1371/journal.pone.0099962
– ident: e_1_2_10_72_1
  doi: 10.1681/ASN.2016020177
– ident: e_1_2_10_5_1
  doi: 10.1016/j.freeradbiomed.2004.05.032
– ident: e_1_2_10_103_1
  doi: 10.1111/sji.12055
– ident: e_1_2_10_90_1
  doi: 10.1164/rccm.201509-1863OC
– ident: e_1_2_10_100_1
  doi: 10.1016/j.vaccine.2010.10.045
– ident: e_1_2_10_30_1
  doi: 10.1038/gene.2014.77
– ident: e_1_2_10_38_1
  doi: 10.1002/eji.200737855
– ident: e_1_2_10_13_1
  doi: 10.1590/S1806-37132008001100012
– ident: e_1_2_10_14_1
  doi: 10.1136/oem.55.7.496
– ident: e_1_2_10_51_1
  doi: 10.3109/08820139.2016.1153650
– volume: 8
  start-page: 641
  year: 2008
  ident: e_1_2_10_64_1
  article-title: Polymorphisms in long noncoding RNA H19 contribute to the protective effects of coal workers’ pneumoconiosis in a Chinese population
  publication-title: PLoS One
– ident: e_1_2_10_55_1
  doi: 10.1111/iji.12212
– ident: e_1_2_10_107_1
  doi: 10.1016/j.immuni.2009.02.007
– ident: e_1_2_10_37_1
  doi: 10.1165/rcmb.2009-0211OC
– ident: e_1_2_10_93_1
  doi: 10.1001/jama.1938.02790310022008
– ident: e_1_2_10_114_1
  doi: 10.4084/mjhid.2014.015
– volume: 113
  start-page: 643
  year: 1976
  ident: e_1_2_10_4_1
  article-title: Silicosis
  publication-title: Am Rev Respir Dis
– ident: e_1_2_10_21_1
  doi: 10.1016/j.trstmh.2009.03.014
– ident: e_1_2_10_27_1
  doi: 10.1093/hmg/ddx365
– ident: e_1_2_10_50_1
  doi: 10.1016/j.clinbiochem.2014.04.009
– ident: e_1_2_10_116_1
  doi: 10.4238/2015.July.31.8
– ident: e_1_2_10_47_1
  doi: 10.1016/j.gene.2015.07.025
– ident: e_1_2_10_42_1
  doi: 10.1006/taap.2001.9124
– ident: e_1_2_10_68_1
  doi: 10.1182/blood-2010-07-273417
– ident: e_1_2_10_75_1
  doi: 10.1371/journal.pone.0147005
– ident: e_1_2_10_101_1
  doi: 10.1111/j.1399-0039.2006.00566.x
– ident: e_1_2_10_74_1
  doi: 10.1164/ajrccm.165.4.2106009
– ident: e_1_2_10_110_1
  doi: 10.1054/tube.2001.0307
– ident: e_1_2_10_119_1
  doi: 10.1289/ehp.99107s5793
– ident: e_1_2_10_86_1
  doi: 10.1539/joh.L8006
– ident: e_1_2_10_20_1
  doi: 10.1046/j.1365-2249.2003.02171.x
– ident: e_1_2_10_39_1
  doi: 10.1002/1529-0131(200110)44:10<2296::AID-ART392>3.0.CO;2-9
– ident: e_1_2_10_79_1
  doi: 10.2217/pgs-2016-0085
– ident: e_1_2_10_41_1
  doi: 10.1002/1097-0274(200103)39:3<286::AID-AJIM1016>3.0.CO;2-7
– ident: e_1_2_10_118_1
  doi: 10.1128/IAI.00443-12
– ident: e_1_2_10_10_1
  doi: 10.1016/j.rcl.2016.05.015
– ident: e_1_2_10_48_1
  doi: 10.1016/j.cyto.2012.06.006
– ident: e_1_2_10_58_1
  doi: 10.1016/j.archoralbio.2015.06.018
– ident: e_1_2_10_40_1
  doi: 10.4049/jimmunol.175.8.5333
– ident: e_1_2_10_80_1
  doi: 10.1097/AJP.0000000000000048
– ident: e_1_2_10_113_1
  doi: 10.1007/s11033-014-3741-1
– ident: e_1_2_10_28_1
  doi: 10.1038/s41467-017-00257-5
– ident: e_1_2_10_112_1
  doi: 10.1016/j.tube.2005.03.001
– volume: 117
  start-page: 621
  issue: 4
  year: 1978
  ident: e_1_2_10_26_1
  article-title: Tuberculosis in twins: a re‐analysis of the Prophit survey
  publication-title: Am Rev Respir Dis
– ident: e_1_2_10_17_1
  doi: 10.1016/j.biomaterials.2011.12.008
– ident: e_1_2_10_29_1
  doi: 10.1371/journal.ppat.1004426
– ident: e_1_2_10_49_1
  doi: 10.1038/sj.gene.6364133
– volume: 4
  start-page: 36
  year: 2012
  ident: e_1_2_10_7_1
  article-title: Silicose: Mecanismos De Atuação Da Partícula De Sílica No Tecido Pulmonar
  publication-title: Interdiscip J Exp Stud
– ident: e_1_2_10_91_1
  doi: 10.1089/dna.2018.4370
– volume: 47
  start-page: 549
  issue: 6
  year: 1943
  ident: e_1_2_10_25_1
  article-title: Twin studies on the significance of genetic factors in tuberculosis
  publication-title: Am Rev Tuberc Pulm Dis
– volume: 23
  start-page: 455
  year: 2013
  ident: e_1_2_10_56_1
  article-title: Single‐nucleotide polymorphisms of TNFA and IL1 in allergic rhinitis
  publication-title: J Investig Allergol Clin Immunol
– volume-title: Gohnet Newsletter
  year: 2007
  ident: e_1_2_10_3_1
– ident: e_1_2_10_16_1
  doi: 10.1183/09031936.06.00132505
– ident: e_1_2_10_109_1
  doi: 10.1111/j.1440-1843.2007.01108.x
– ident: e_1_2_10_18_1
  doi: 10.1164/ajrccm.157.5.9707141
– ident: e_1_2_10_78_1
  doi: 10.3892/ijmm.2012.996
– volume: 7
  start-page: 20
  year: 2012
  ident: e_1_2_10_85_1
  article-title: Molecular evaluation of the IFN γ +874, TNF α ‐308, and IL‐1Ra VNTR sequences in silicosis
  publication-title: Mædica
– ident: e_1_2_10_84_1
  doi: 10.3923/pjbs.2014.419.423
– ident: e_1_2_10_88_1
  doi: 10.1038/ng.2609
– ident: e_1_2_10_45_1
  doi: 10.1016/j.etp.2009.11.006
– ident: e_1_2_10_54_1
  doi: 10.1186/1471-2350-15-8
– ident: e_1_2_10_69_1
  doi: 10.1056/NEJMc071324
– ident: e_1_2_10_95_1
  doi: 10.1016/j.smim.2014.09.004
– ident: e_1_2_10_99_1
  doi: 10.1111/2049-632X.12075
– ident: e_1_2_10_105_1
  doi: 10.1086/344891
– ident: e_1_2_10_120_1
  doi: 10.1590/S1415-47572014000200003
– ident: e_1_2_10_9_1
  doi: 10.1016/1043-4666(93)90024-Y
– ident: e_1_2_10_77_1
  doi: 10.1371/journal.pone.0140952
– ident: e_1_2_10_6_1
  doi: 10.1080/08958370050164842
– ident: e_1_2_10_57_1
  doi: 10.1007/s00251-002-0445-9
– ident: e_1_2_10_34_1
  doi: 10.1186/s12989-014-0069-x
– ident: e_1_2_10_71_1
  doi: 10.1111/eci.12702
– ident: e_1_2_10_43_1
  doi: 10.1183/09031936.00075107
– ident: e_1_2_10_92_1
  doi: 10.1016/j.gene.2018.03.098
– ident: e_1_2_10_82_1
  doi: 10.1016/j.cyto.2011.09.021
– ident: e_1_2_10_62_1
  doi: 10.1164/ajrccm.165.5.2010050
– volume: 32
  start-page: 219
  year: 2005
  ident: e_1_2_10_111_1
  article-title: Autoimmunity and tuberculosis. Opposite association with TNF polymorphism
  publication-title: J Rheumatol
– ident: e_1_2_10_106_1
  doi: 10.1016/j.smim.2014.09.011
– ident: e_1_2_10_66_1
  doi: 10.1016/S0140-6736(96)07336-9
– ident: e_1_2_10_94_1
  doi: 10.2471/BLT.15.163550
– ident: e_1_2_10_46_1
  doi: 10.1002/ajim.20616
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Snippet Introduction Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according...
Silicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according to the...
IntroductionSilicosis is a fibrotic lung disease resulting from the inhalation of crystalline silica and can be classified as simple or complicated according...
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StartPage 74
SubjectTerms Alleles
association study
Brazil
Confidence intervals
Crystal structure
Crystallinity
Cytokines
Exposure
Female
Fibrosis
Gene polymorphism
Genetic Predisposition to Disease
Genetic Variation
genetics
Genotype
Humans
Inflammation
Inhalation
Interleukin 1
Interleukin-1alpha - genetics
Interleukin-1beta - genetics
Interleukins
Lung diseases
Male
Nucleotides
Occupational Exposure
Polymerase chain reaction
Polymorphism
Polymorphism, Single Nucleotide
Respiration
Restriction fragment length polymorphism
Risk Factors
Silica
Silicon dioxide
Silicon Dioxide - toxicity
Silicosis
Silicosis - genetics
Single-nucleotide polymorphism
Tuberculosis
Tuberculosis - genetics
Tumor Necrosis Factor-alpha - genetics
Title Interleukin 1α and 1β gene variations are associated with tuberculosis in silica exposed subjects
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fajim.23066
https://www.ncbi.nlm.nih.gov/pubmed/31692000
https://www.proquest.com/docview/2321251727
https://www.proquest.com/docview/2312548714
Volume 63
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