Breast Amide Proton Transfer Imaging at 3 T: Diagnostic Performance and Association With Pathologic Characteristics

• Published in: Journal of magnetic resonance imaging Vol. 57; no. 3; pp. 824 - 833
• Main Authors: Liu, Zhou, Wen, Jie, Wang, Meng, Ren, Ya, Yang, Qian, Qian, Long, Luo, Honghong, Feng, Sha, He, Cuiju, Liu, Xin, Wu, Yin, Luo, Dehong
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.03.2023; Wiley Subscription Services, Inc
• Subjects: amide proton transfer; Amides; Biomarkers; Breast cancer; Breast carcinoma; breast neoplasm; Breast Neoplasms - metabolism; Diagnostic systems; Estrogen receptors; Estrogens; Female; Field strength; Growth factors; histologic grade; Humans; Ki-67 Antigen - metabolism; Ki‐67; Lesions; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Malignancy; Medical imaging; Progesterone; Prospective Studies; Protons; Receptors; Statistical analysis; Statistical tests; Tumors; Variance analysis; amide proton transfer; breast neoplasm; Ki-67; histologic grade

Background Amide proton transfer (APT) imaging has been increasingly applied in tumor characterization. However, its value in evaluating breast cancer remains undetermined. Purpose To assess the diagnostic performance of APT imaging in breast cancer and its association with prognostic histopathologi...