Prospective Evaluation of Virtual MR Elastography With Diffusion‐Weighted Imaging in Subjects With Nonalcoholic Fatty Liver Disease

• Published in: Journal of magnetic resonance imaging Vol. 56; no. 5; pp. 1448 - 1456
• Main Authors: Hanniman, Elyisha, Costa, Andreu F., Bowen, Chris V., Abdolell, Mohamed, Stueck, Ashley, McLeod, Magnus, Peltekian, Kevork, Rioux, James, Clarke, Sharon E.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.11.2022; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Biopsy; Cirrhosis; Cross-Sectional Studies; Diffusion; Diffusion coefficient; diffusion‐weighted imaging; Elasticity Imaging Techniques - methods; Evaluation; Fatty liver; Fibrosis; Field strength; Humans; Least squares method; Liver; Liver - diagnostic imaging; Liver - pathology; Liver cancer; Liver cirrhosis; Liver Cirrhosis - diagnostic imaging; Liver Cirrhosis - pathology; Liver diseases; liver fibrosis; Magnetic resonance; magnetic resonance elastography; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Middle Aged; Non-alcoholic Fatty Liver Disease - diagnostic imaging; Non-alcoholic Fatty Liver Disease - pathology; nonalcoholic fatty liver disease; Proton density (concentration); Protons; Shear modulus; Statistical analysis; Statistical tests; Steatosis; Stiffness; Variance analysis; liver fibrosis; nonalcoholic fatty liver disease; diffusion-weighted imaging; magnetic resonance elastography

Background Non‐alcoholic fatty liver disease (NAFLD) is increasingly common worldwide and can lead to the development of cirrhosis, liver failure and cancer. Virtual magnetic resonance elastography (VMRE), which is based on a shifted apparent diffusion coefficient (sADC), is a potential noninvasive...