Amide Proton Transfer‐Weighted Imaging in Assessing the Aggressive and Proliferative Potential of Bladder Cancer

• Published in: Journal of magnetic resonance imaging Vol. 61; no. 2; pp. 704 - 712
• Main Authors: Kong, Lingmin, Li, Hui, Cai, Qian, Cao, Wenxin, Chen, Yanling, Weng, Bei, Li, Meiqin, Zhang, Min, Qian, Long, Guo, Yan, Ling, Jian, Wen, Zhihua, Wang, Huanjun
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.02.2025; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Aged, 80 and over; Amide proton transfer imaging; Amides; Bladder; Bladder cancer; Cancer; Cell Proliferation; Correlation coefficient; Correlation coefficients; Decision making; ErbB-2 protein; Feasibility Studies; Female; Field strength; Growth factors; HER2; Humans; Ki-67 Antigen - metabolism; Ki‐67; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Malignancy; Medical imaging; Middle Aged; MRI; Patients; Protons; Receptor, ErbB-2 - metabolism; Reproducibility of Results; Retrospective Studies; Statistical analysis; Statistical tests; Urinary Bladder - diagnostic imaging; Urinary Bladder - pathology; Urinary Bladder Neoplasms - diagnostic imaging; Ki‐67; Amide proton transfer imaging; HER2; MRI; Bladder cancer

Background Ki‐67 and human epidermal growth factor receptor 2 (HER2) are known oncogenes involved in bladder cancer (BCa) patient risk stratification. Preoperative assessment of their expression level can assist in clinical treatment decision‐making. Recently, amide proton transfer‐weighted (APTw) M...