Disrupted functional connectivity and activity in the white matter of the sensorimotor system in patients with pontine strokes

• Published in: Journal of magnetic resonance imaging Vol. 49; no. 2; pp. 478 - 486
• Main Authors: Wang, Jingjuan, Yang, Zhipeng, Zhang, Miao, Shan, Yi, Rong, Dongdong, Ma, Qingfeng, Liu, Hesheng, Wu, Xi, Li, Kuncheng, Ding, Zhaohua, Lu, Jie
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.02.2019; Wiley Subscription Services, Inc
• Subjects: Adult; Aged; Anisotropy; Biomarkers; Biomarkers - metabolism; Case-Control Studies; Correlation analysis; Diffusion Tensor Imaging; Ethics; Female; Field strength; Functional magnetic resonance imaging; Humans; Image processing; Informed consent; Lesions; Magnetic Resonance Imaging; Male; Medical imaging; Middle Aged; motor deficit; Neuroimaging; Oxygen - blood; Oxygenation; Patients; Pons - diagnostic imaging; pontine stroke; Power spectra; Predictions; Prefrontal cortex; Prospective Studies; Regression analysis; Sensorimotor Cortex - diagnostic imaging; Sensorimotor system; Statistical analysis; Statistical tests; Stroke; Stroke - diagnostic imaging; Substantia alba; Thalamus; white matter; White Matter - diagnostic imaging; motor deficit; white matter; sensorimotor system; pontine stroke

Background White matter (WM) blood oxygenation level‐dependent (BOLD) signals are reported to be related to neural activity. However, sensitivity of WM BOLD signals to disease remains unclear. Purpose To investigate WM BOLD signal changes, directional variations of resting‐state correlations in sens...