Chemoselectivity Switching in the Rhodium‐Catalyzed Reactions of 4‐Substituted‐1‐sulfonyl‐1,2,3‐triazoles with Allenols: Noticeable Differences between 4‐Acyl‐ and 4‐Aryl‐Triazoles

• Published in: Advanced synthesis & catalysis Vol. 361; no. 5; pp. 1160 - 1165
• Main Authors: Alcaide, Benito, Almendros, Pedro, Fernández, Israel, del Campo, Teresa Martínez, Palop, Guillermo, Toledano‐Pinedo, Mireia, Delgado‐Martínez, Patricia
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 05.03.2019; Wiley Subscription Services, Inc
• Subjects: allenes; Aromatic compounds; Chemical reactions; Chemistry; Chemistry, Applied; Chemistry, Organic; heterocycles; homogeneous catalysis; ketones; Physical Sciences; Rhodium; Science & Technology; Substitutes; Triazoles; allenes; homogeneous catalysis; heterocycles; PRODUCTS; BONDS; DIVERGENT SYNTHESIS; REACTIVITY; TERMINAL ALKYNES; ketones; REARRANGEMENTS; rhodium

Tunable chemoselectivity (O‐ versus C‐attack) in the rhodium‐catalyzed reactions of allenols with 4‐substituted‐1‐sulfonyl‐1,2,3‐triazoles has been achieved through the replacement of the 4‐aryl substituent by a 4‐acetyl moiety.