The indispensable role of pharmacy services and medication therapy management in cystic fibrosis

• Published in: Pediatric pulmonology Vol. 57; no. S1; pp. S17 - S39
• Main Authors: Grant, Jonathan J., McDade, Erin J., Zobell, Jeffery T., Young, David C.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2022
• Subjects: Ambulatory care; Cystic fibrosis; Cystic Fibrosis - drug therapy; Drug stores; Drug therapy; Humans; Medication Therapy Management; medications; Pharmaceutical Services; pharmacist; Pharmacists; pharmacodynamics; pharmacokinetics; pharmacy care; Pharmacy Technicians; Professional Role; pharmacist; pharmacokinetics; pharmacy care; cystic fibrosis; pharmacodynamics; medications
• ISSN: 8755-6863; 1099-0496
• DOI: 10.1002/ppul.25613

Care for people with cystic fibrosis (PWCF) is highly complex and requires a multidisciplinary approach where the pharmacist plays a vital role. The purpose of this manuscript is to serve as a guideline for pharmacists and pharmacy technicians who provide care for PWCF by providing background and current recommendations for the use of cystic fibrosis (CF)‐specific medications in both the acute and ambulatory care settings. The article explores current literature surrounding the role of pharmacists and pharmacy technicians, proven pharmacy models to emulate, and pharmacokinetic idiosyncrasies unique to the CF population while also identifying areas of future research. Clinical recommendations for the use of CF‐specific medications are broken down by organ system including mechanism of action, adverse events, dosages, and monitoring parameters. The article also includes quick reference tables essential to the acute and chronic medication therapy management of PWCF.