The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects - Schwandt, Melanie L; Cortes, Carlos R; Kwako, Laura E; George, David T; Momenan, Reza; Sinha, Rajita; Grigoriadis, Dimitri E; Pich, Emilio Merlo; Leggio, Lorenzo; Heilig, Markus (Neuropsychopharmacology (New York, N.Y.), 2016)
Keywords: Adrenalectomy; Adrenocorticotropic Hormone - blood; Adult; Aged; Alcoholism; Alcoholism - complications; Alcoholism - diagnostic imaging; Alcoholism - drug therapy; Animals; Anxiety - diagnostic imaging; Anxiety - drug therapy; Anxiety - etiology; Azabicyclo Compounds - therapeutic use; Biomarkers; Brain research; Craving - drug effects; Disease Models, Animal; Double-Blind Method; Female; Humans; Hydrocortisone - blood; Image Processing, Computer-Assisted; Imagery (Psychotherapy); Mental depression; Middle Aged; Neurosciences; Original; Oxadiazoles - therapeutic use; Oxygen - blood; Psychiatric Status Rating Scales; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors; Retrospective Studies; Single-Blind Method; Young Adult; United States--US