Medication adherence in first episode psychosis: the role of pre‐onset subthreshold symptoms

• Published in: Acta psychiatrica Scandinavica Vol. 139; no. 4; pp. 336 - 347
• Main Authors: Daneault, J.‐G., Maraj, A., Lepage, M., Malla, A., Schmitz, N., Iyer, S. N., Joober, R., Shah, J. L.
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.04.2019
• Subjects: Adolescent; Adult; Antipsychotic Agents - administration & dosage; Antipsychotics; clinical high risk; Drug use; family involvement; Female; first episode psychosis; Humans; Male; Medication adherence; Medication Adherence - statistics & numerical data; Patient compliance; Patients; Prodromal Symptoms; Psychosis; Psychotic Disorders - drug therapy; Psychotic Disorders - epidemiology; Psychotic Disorders - physiopathology; Psychotropic drugs; Quebec - epidemiology; Regression analysis; Risk; substance use disorder; Young Adult; Quebec; substance use disorder; first episode psychosis; medication adherence; family involvement; clinical high risk

Objective The experience of pre‐onset subthreshold psychotic symptoms (STPS, signifying a clinical high‐risk state) in first episode psychosis (FEP) predicts poorer outcomes during treatment, possibly through differential adherence to medication. We explored whether adherence differs between FEP pat...