Current status and temporal trend of disease burden of thyroid cancer in China from 1990 to 2019

• Published in: Asia-Pacific journal of clinical oncology Vol. 19; no. 1; pp. 196 - 205
• Main Authors: Zhang, Meng‐Ni, Liang, Xiao‐Yu, Li, Mao‐Ting, Zhi, Xin‐Yue, Yan, Qiu‐Yu, Zhu, Hong, Xie, Juan
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.02.2023
• Subjects: Age; age‐sex distribution; cancer burden; China - epidemiology; Cost of Illness; disability‐adjusted life years; epidemiological distribution; Female; Gender; Gender differences; Humans; Incidence; Male; Males; Mortality; Public health; Quality-Adjusted Life Years; Risk factors; Thyroid cancer; Thyroid Neoplasms - epidemiology; China; cancer burden; thyroid cancer; epidemiological distribution; age-sex distribution; disability-adjusted life years
• DOI: 10.1111/ajco.13800
• ISSN: 1743-7555

Objective Thyroid cancer has been an increasingly high‐profile public health issue. Comprehensive assessment for its disease burden seems particularly important for understanding health priorities and hinting high‐risk populations. Methods We estimated the age‐sex‐specific thyroid cancer burden and its temporal trend in China from 1990 to 2019 by following the general methods from the global burden of disease (GBDs) 2019 Study. And Joinpoint regression model, the Cox‐Stuart trend test, and Cochran‐Armitage test were applied for the analysis of temporal and age trend. The Mantel‐Haenszel statistical method was used to compare the gender difference. Results From 1990 to 2019, the age‐standardized incidence rate of thyroid cancer in China has almost doubled to 2.05 per 100,000. Although the mortality rate and DALY rate kept leveling off, they presented a downtrend among females, while an upward trend in males. While the average annual percentage changes of those metrics all became deline since 2010 than the previous years. With age advancing, the rates of incidence, mortality, and DALYs for both sexes all presented linear fashion increases, which was particularly typical among males. Conclusion Given the serious trend and gender‐age heterogeneity of Chinese thyroid cancer burden, male gender and advanced age may be related to poor prognosis of thyroid cancer, and strengthening primary prevention and exploring the underlying risk factors should be among the top priorities. Although the incidence of thyroid cancer in Chinese population was lower than the global average, given the huge population base, the burden of thyroid cancer disease in China cannot be ignored, especially the fatal burden among males in China.