Effect of intensive glycaemic control on fibrinogen plasma concentrations in patients with Type II diabetes mellitus. Relation with β-fibrinogen genotype

• Published in: Diabetologia Vol. 41; no. 11; pp. 1270 - 1273
• Main Authors: CERIELLO, A, MERCURI, F, FABBRO, D, GIACOMELLO, R, STEL, G, TABOGA, C, TONUTTI, L, MOTZ, E, DAMANTE, G
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.11.1998
• Subjects: Biological and medical sciences; Blood Glucose - metabolism; C-Reactive Protein - metabolism; Deoxyribonuclease HindIII; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - genetics; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Female; Fibrinogen - genetics; Fibrinogen - metabolism; Genotype; Glycated Hemoglobin A - analysis; Humans; Hypoglycemic Agents - therapeutic use; Insulin - therapeutic use; Male; Management. Various non-drug treatments. Langerhans islet grafts; Medical sciences; Middle Aged; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Endocrinopathy; Human; Hyperglycemia; Fibrinogen; Genotype; Non insulin dependent diabetes; Glycemia; Quantitative analysis; Blood plasma; Polymorphism

Recent studies show that in diabetic subjects an increase of plasma fibrinogen concentration is associated with a high risk of cardiovascular complications. Environmental and genetic factors contribute to the plasma fibrinogen concentration. Several studies indicate a relation between the polymorphi...