New Drug for Chronic Myeloid Leukemia Might Stimulate the Market
The evolution of treatment options over the past 20 years has provided for a normal life expectancy for most patients with chronic myeloid leukemia. Currently approved tyrosine kinase inhibitors mainly differ in potency and side effect profile. Flumatinib goes for deep responses and good tolerabilit...
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Published in | Clinical cancer research Vol. 27; no. 1; pp. 3 - 4 |
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Main Author | |
Format | Journal Article |
Language | English |
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United States
01.01.2021
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Abstract | The evolution of treatment options over the past 20 years has provided for a normal life expectancy for most patients with chronic myeloid leukemia. Currently approved tyrosine kinase inhibitors mainly differ in potency and side effect profile. Flumatinib goes for deep responses and good tolerability.
See related article by Zhang et al., p. 70 |
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AbstractList | The evolution of treatment options over the past 20 years has provided for a normal life expectancy for most patients with chronic myeloid leukemia. Currently approved tyrosine kinase inhibitors mainly differ in potency and side effect profile. Flumatinib goes for deep responses and good tolerability.
. The evolution of treatment options over the past 20 years has provided for a normal life expectancy for most patients with chronic myeloid leukemia. Currently approved tyrosine kinase inhibitors mainly differ in potency and side effect profile. Flumatinib goes for deep responses and good tolerability.See related article by Zhang et al., p. 70.The evolution of treatment options over the past 20 years has provided for a normal life expectancy for most patients with chronic myeloid leukemia. Currently approved tyrosine kinase inhibitors mainly differ in potency and side effect profile. Flumatinib goes for deep responses and good tolerability.See related article by Zhang et al., p. 70. The evolution of treatment options over the past 20 years has provided for a normal life expectancy for most patients with chronic myeloid leukemia. Currently approved tyrosine kinase inhibitors mainly differ in potency and side effect profile. Flumatinib goes for deep responses and good tolerability. See related article by Zhang et al., p. 70 |
Author | Müller, Martin C. |
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Cites_doi | 10.1038/s41375-020-0776-2 10.1038/leu.2014.153 10.1038/leu.2010.169 10.1158/1078-0432.CCR-20-1600 10.1200/JCO.2009.26.3087 |
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References | Zhang (2022061101492711500_bib1) 2021; 27 Marin (2022061101492711500_bib2) 2010; 28 Hochhaus (2022061101492711500_bib4) 2020; 34 Hanfstein (2022061101492711500_bib3) 2014; 28 Luo (2022061101492711500_bib5) 2010; 24 32928796 - Clin Cancer Res. 2021 Jan 1;27(1):70-77 32928796 - Clin Cancer Res. 2020 Sep 14 |
References_xml | – volume: 34 start-page: 966 year: 2020 ident: 2022061101492711500_bib4 article-title: European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia publication-title: Leukemia doi: 10.1038/s41375-020-0776-2 – volume: 28 start-page: 1988 year: 2014 ident: 2022061101492711500_bib3 article-title: Velocity of early BCR-ABL transcript elimination as an optimized predictor of outcome in chronic myeloid leukemia (CML) patients in chronic phase on treatment with imatinib publication-title: Leukemia doi: 10.1038/leu.2014.153 – volume: 24 start-page: 1807 year: 2010 ident: 2022061101492711500_bib5 article-title: HH-GV-678, a novel selective inhibitor of Bcr-Abl, outperforms imatinib and effectively overrides imatinib resistance publication-title: Leukemia doi: 10.1038/leu.2010.169 – volume: 27 start-page: 70 year: 2021 ident: 2022061101492711500_bib1 article-title: Flumatinib versus imatinib for newly diagnosed chronic phase chronic myeloid leukemia: a phase 3, randomized, open-label, multi-center FESTnd study publication-title: Clin Cancer Res doi: 10.1158/1078-0432.CCR-20-1600 – volume: 28 start-page: 2381 year: 2010 ident: 2022061101492711500_bib2 article-title: Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib publication-title: J Clin Oncol doi: 10.1200/JCO.2009.26.3087 – reference: 32928796 - Clin Cancer Res. 2021 Jan 1;27(1):70-77 – reference: 32928796 - Clin Cancer Res. 2020 Sep 14;: |
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Title | New Drug for Chronic Myeloid Leukemia Might Stimulate the Market |
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