Role of FDG PET/CT in investigating the mechanisms underlying atherosclerotic plaque formation and evolution

• Published in: Revista espanola de medicina nuclear e imagen molecular Vol. 32; no. 4; pp. 246 - 252
• Main Authors: Marzola, M.C., Saboury, B., Chondrogiannis, S., Rampin, L., Grassetto, G., Ferretti, A., Alavi, A., Rubello, D.
• Format: Journal Article
• Language: English
• Published: Spain Elsevier España 01.07.2013
• Subjects: Aterosclerosis; Atherosclerosis; Células inflamatorias; Disease Progression; Etiology; Etiología; FDG PET/CT; FDG PET/TC; Fluorodeoxyglucose F18; Humans; Imagen molecular; Inflammation - complications; Inflammation cells; Molecular imaging; Multimodal Imaging; Placa estable; Placa vulnerable; Plaque, Atherosclerotic - complications; Plaque, Atherosclerotic - diagnostic imaging; Positron-Emission Tomography; Radiopharmaceuticals; Stable plaque; Tomography, X-Ray Computed; Vulnerable plaque; Molecular imaging; FDG PET/TC; Placa estable; Células inflamatorias; FDG PET/CT; Vulnerable plaque; Aterosclerosis; Etiology; Atherosclerosis; Inflammation cells; Stable plaque; Etiología; Imagen molecular; Placa vulnerable

This review article is focused on the role of FDG-PET/CT in visualizing atherosclerosis and on the relevance of inflammatory cells such as macrophages and T-lymphocytes in the formation of the atherosclerotic plaque. The vulnerability of the inflammatory plaque and the risk derived from the provocat...