Vitamin K2 supplementation and arterial stiffness among renal transplant recipients—a single-arm, single-center clinical trial

• Published in: Journal of the American Society of Hypertension Vol. 11; no. 9; pp. 589 - 597
• Main Authors: Mansour, Anthony G., Hariri, Essa, Daaboul, Yazan, Korjian, Serge, El Alam, Andrew, Protogerou, Athanase D., Kilany, Hala, Karam, Albert, Stephan, Antoine, Bahous, Sola Aoun
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2017
• Subjects: Adult; Biomarkers - blood; Calcium-Binding Proteins - blood; Dietary Supplements; Extracellular Matrix Proteins - blood; Female; Humans; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - therapy; Kidney Transplantation; Male; Matrix Gla Protein; Menaquinone; Middle Aged; Pilot Projects; Prevalence; Prospective Studies; Pulse Wave Analysis; pulse wave velocity; Renal Dialysis; Treatment Outcome; Vascular Calcification - blood; Vascular Calcification - drug therapy; Vascular Calcification - epidemiology; Vascular Stiffness - drug effects; Vitamin K - blood; Vitamin K 2 - therapeutic use; Vitamin K Deficiency - blood; Vitamin K Deficiency - drug therapy; Vitamin K Deficiency - epidemiology; Vitamins - therapeutic use; pulse wave velocity; Menaquinone

Subclinical vitamin K deficiency is prevalent among renal transplant recipients and is associated with an increased risk of cardiovascular disease. However, the association between vitamin K supplementation and improvement of arterial stiffness has not been explored in the renal transplant populatio...