Combined Measurement of D-Dimer and C-Reactive Protein Levels: Highly Accurate for Diagnosing Chronic Periprosthetic Joint Infection

• Published in: The Journal of arthroplasty Vol. 35; no. 1; pp. 229 - 234
• Main Authors: Qin, Leilei, Li, Feilong, Gong, Xuan, Wang, Jiawei, Huang, Wei, Hu, Ning
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2020
• Subjects: Arthroplasty, Replacement, Hip - adverse effects; Biomarkers; Blood Sedimentation; C-reactive protein; C-Reactive Protein - analysis; D-dimer; diagnostic test; erythrocyte sedimentation rate; Fibrin Fibrinogen Degradation Products; Humans; periprosthetic joint infection; Prospective Studies; Prosthesis-Related Infections - diagnosis; Prosthesis-Related Infections - surgery; Sensitivity and Specificity; Synovial Fluid - chemistry; erythrocyte sedimentation rate; periprosthetic joint infection; D-dimer; C-reactive protein; diagnostic test

Diagnosis of chronic periprosthetic joint infection (PJI) can be challenging and elusive in the absence of a gold standard. D-dimer plays an important role in inflammation that occurs during infections and therefore could be a valuable biomarker for PJI. This study aims to investigate the sensitivit...