Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involves distinct Toll-like receptors - Chiurchiù, Valerio; Leuti, Alessandro; Cencioni, Maria Teresa; Albanese, Maria; De Bardi, Marco; Bisogno, Tiziana; Centonze, Diego; Battistini, Luca; Maccarrone, Mauro (Pharmacological research, 2016)
Keywords: Adult; Arachidonic Acids - therapeutic use; Bioactive lipids; Endocannabinoids; Endocannabinoids - metabolism; Endocannabinoids - therapeutic use; Female; Humans; Immunologic Factors - therapeutic use; Immunomodulation; Immunosuppressive Agents - therapeutic use; Interleukin-12 - metabolism; Interleukin-6 - metabolism; Lipids - therapeutic use; Male; Monocytes - drug effects; Monocytes - metabolism; Multiple sclerosis; Multiple Sclerosis - drug therapy; Multiple Sclerosis - metabolism; Polyunsaturated Alkamides - therapeutic use; Signal Transduction - drug effects; Toll-Like Receptor 2 - metabolism; Toll-Like Receptor 4 - metabolism; Toll-like receptors; Tumor Necrosis Factor-alpha - metabolism; Toll-like receptors; Multiple sclerosis; Bioactive lipids; Immunomodulation; Endocannabinoids