Rheumatoid arthritis: From synovium biology to cell-based therapy

• Published in: Cytotherapy (Oxford, England) Vol. 24; no. 4; pp. 365 - 375
• Main Authors: Debreova, Michaela, Culenova, Martina, Smolinska, Veronika, Nicodemou, Andreas, Csobonyeiova, Maria, Danisovic, Lubos
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.04.2022
• Subjects: Arthritis, Rheumatoid - therapy; autoimmunity; Biology; cell therapy; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells - physiology; mesenchymal/medicinal stem/signaling cells; rheumatoid arthritis; synovial biochemistry; Synovial Membrane - pathology; synovial biochemistry; autoimmunity; rheumatoid arthritis; cell therapy; mesenchymal/medicinal stem/signaling cells

Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the synovial joints and, if not treated properly, can lead to multiple progressive articular and extra-articular damage. Its pathogenesis is primarily associated with an inadequate immune response and dysregulated cytokine prod...