Prediction of citrullination sites by incorporating k-spaced amino acid pairs into Chou's general pseudo amino acid composition

• Published in: Gene Vol. 664; pp. 78 - 83
• Main Authors: Ju, Zhe, Wang, Shi-Yun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 20.07.2018
• Subjects: Algorithms; Arginine - metabolism; Citrullination; Computational Biology - methods; Genetic Testing; Humans; K-spaced amino acid pair; Models, Biological; Post-translational modification; Proteomics - methods; Support vector machine; Post-translational modification; Citrullination; ACC; PTM; SVM; Support vector machine; MCC; AUC; K-spaced amino acid pair; RBF; CKSAAP; Sn; Sp

As one of the most important and common protein post-translational modifications, citrullination plays a key role in regulating various biological processes and is associated with several human diseases. The accurate identification of citrullination sites is crucial for elucidating the underlying mo...