Taxane-based Induction Chemotherapy Plus Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma: Prospective Results from a Non-endemic Cohort

• Published in: Clinical oncology (Royal College of Radiologists (Great Britain)) Vol. 31; no. 12; pp. 850 - 857
• Main Authors: Ghosh-Laskar, S., Pilar, A., Prabhash, K., Joshi, A., Agarwal, J.P., Gupta, T., Budrukkar, A., Murthy, V., Swain, M., Noronha, V., Patil, V.M., Pai, P., Nair, D., Chaukar, D.A., Thiagarajan, S., Pantvaidya, G., Deshmukh, A., Chaturvedi, P., Nair, S., D‘Cruz, A.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2019
• Subjects: Adolescent; Adult; Aged; Chemoradiotherapy - methods; Cohort Studies; Disease-Free Survival; Female; Humans; Induction chemotherapy; Induction Chemotherapy - methods; intensity-modulated radiotherapy; Male; Middle Aged; nasopharyngeal cancer; Nasopharyngeal Carcinoma - pathology; Nasopharyngeal Carcinoma - radiotherapy; outcomes; Prospective Studies; Taxoids - pharmacology; Taxoids - therapeutic use; Treatment Outcome; Young Adult; Induction chemotherapy; intensity-modulated radiotherapy; nasopharyngeal cancer; outcomes

To report the outcomes of induction chemotherapy (ICT) followed by chemoradiotherapy (CTRT) for a large cohort of locoregionally advanced nasopharyngeal cancer (LA-NPC) from a non-endemic region. Between January 2008 and July 2015, 201 patients with histologically proven, non-metastatic NPC were tre...