The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers
Epigenome aberrations have been observed in tobacco-associated human malignancies. (-)-epigallocatechin-3-gallate (EGCG) has been proven to modulate gene expression by targeting DNA methyltransferases (DNMTs) through a proposed mechanism involving the gallate moiety of EGCG. We show that gallic acid...
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Published in | Oncotarget Vol. 9; no. 1; pp. 361 - 374 |
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Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Impact Journals LLC
02.01.2018
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Subjects | |
Online Access | Get full text |
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