Bromodomain inhibition by JQ1 suppresses lipopolysaccharide-stimulated interleukin-6 secretion in multiple myeloma cells

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Published inCytokine (Philadelphia, Pa.) Vol. 71; no. 2; pp. 415 - 417
Main Authors Ghurye, Rohit R., Stewart, Helen J.S., Chevassut, Timothy J.
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.02.2015
Subjects
Aged
Aged, 80 and over
Antibodies, Monoclonal - chemistry
Azepines - chemistry
Cell Survival
Enzyme-Linked Immunosorbent Assay
Female
Gene Expression Regulation, Neoplastic
Humans
Interleukin-6 - metabolism
Lipopolysaccharides - chemistry
Male
Multiple Myeloma - metabolism
Protein Structure, Tertiary
Real-Time Polymerase Chain Reaction
Triazoles - chemistry
Online AccessGet full text

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Author Ghurye, Rohit R.
Stewart, Helen J.S.
Chevassut, Timothy J.
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  givenname: Timothy J.
  surname: Chevassut
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SubjectTerms Aged
Aged, 80 and over
Antibodies, Monoclonal - chemistry
Azepines - chemistry
Cell Survival
Enzyme-Linked Immunosorbent Assay
Female
Gene Expression Regulation, Neoplastic
Humans
Interleukin-6 - metabolism
Lipopolysaccharides - chemistry
Male
Multiple Myeloma - metabolism
Protein Structure, Tertiary
Real-Time Polymerase Chain Reaction
Triazoles - chemistry
Title Bromodomain inhibition by JQ1 suppresses lipopolysaccharide-stimulated interleukin-6 secretion in multiple myeloma cells
URI https://dx.doi.org/10.1016/j.cyto.2014.11.013
https://www.ncbi.nlm.nih.gov/pubmed/25482841
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