Two new dammarane-type triterpene saponins from Korean red ginseng and their anti-inflammatory effects - Vinh, Le Ba; Lee, Yunjeong; Han, Yoo Kyong; Kang, Jong Seong; Park, Jung Up; Kim, Young Ran; Yang, Seo Young; Kim, Young Ho (Bioorganic & medicinal chemistry letters, 2017)
Keywords: 20R-Ginsenoside Rh1 6′-acetate; 6-O-β-d-Glucopyranosyl-20R-protopanaxadiol-3-one; Animals; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - isolation & purification; Anti-Inflammatory Agents - pharmacology; Anti-inflammatory effect; Chemistry; Chemistry, Medicinal; Chemistry, Organic; Chemokines - metabolism; Cyclooxygenase 2 - genetics; Cyclooxygenase 2 - metabolism; Cytokines - metabolism; Dammaranes; Gene Expression - drug effects; Korean red ginseng; Life Sciences & Biomedicine; Lipopolysaccharides - toxicity; Macrophages - cytology; Macrophages - drug effects; Macrophages - metabolism; Magnetic Resonance Spectroscopy; Mice; Molecular Conformation; Nitric Oxide Synthase Type II - genetics; Nitric Oxide Synthase Type II - metabolism; Panax - chemistry; Panax - metabolism; Pharmacology & Pharmacy; Physical Sciences; RAW 264.7 Cells; Republic of Korea; Saponins - chemistry; Saponins - isolation & purification; Saponins - pharmacology; Science & Technology; Triterpenes - chemistry; Anti-inflammatory effect; 20R-Ginsenoside Rh1 6′-acetate; 6-O-β-d-Glucopyranosyl-20R-protopanaxadiol-3-one; Korean red ginseng; CELLS; PANAX-GINSENG; NITRIC-OXIDE SYNTHASE; LEAVES; 6-O-beta-D-Glucopyranosyl-20R-protopanaxadiol-3-one; B TRANSCRIPTIONAL ACTIVITY; INHIBITION; 20R-Ginsenoside Rh1 6'-acetate; INFLAMMATION; GINSENOSIDES; BINDING; CONSTITUENTS