Cellular, transcriptomic and methylome effects of individual and combined exposure to BPA, BPF, BPS on mouse spermatocyte GC-2 cell line
Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway alterations. The presence of bisphenol A (BPA) in the environment has been confirmed and it is about to be replaced by analogues such as bisphenol F (...
Saved in:
| Published in | Toxicology and applied pharmacology Vol. 359; pp. 1 - 11 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
15.11.2018
|
| Online Access | Get full text |
Cover
Loading…
| Abstract | Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway alterations. The presence of bisphenol A (BPA) in the environment has been confirmed and it is about to be replaced by analogues such as bisphenol F (BPF) and bisphenol S (BPS). Whether the BPF and BPS exert similar adverse effects to BPA has become the subject of intense scientific scrutiny. The aim of the present study was to evaluate and compare the cellular, transcriptomic and methylome effects of exposure to BPA, BPF, BPS individually and in combination on GC-2 spermatocyte cell line. The results show that all studied compounds affect cell viability, induce apoptosis and cause cellular damage. BPA, BPF and BPS also influence GC-2 cell steroid receptor and steroidogenesis related genes expressions. In addition to specific molecular mechanisms, all studied compounds also increase global DNA methylation. Exposure to a combination of all the studied compounds caused comparable effects on cell culture to each of them examined separately. These data suggest that exposure to BPA and its main substitutes- BPF and BPS induced multitude of effects and hence, BPF and BPS are not safe alternative to BPA in terms of male reproductive health.
•BPA, BPF and BPS affect GC-2 cell viability•ERs and GPR30 cooperate in mediating the effects of BPF and BPS•Mixture of bisphenols causes comparable effects as single compound.•BPA, BPF and BPS affect global DNA methylation.•BPF and BPS are not safe substitutes to BPA. |
|---|---|
| AbstractList | Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway alterations. The presence of bisphenol A (BPA) in the environment has been confirmed and it is about to be replaced by analogues such as bisphenol F (BPF) and bisphenol S (BPS). Whether the BPF and BPS exert similar adverse effects to BPA has become the subject of intense scientific scrutiny. The aim of the present study was to evaluate and compare the cellular, transcriptomic and methylome effects of exposure to BPA, BPF, BPS individually and in combination on GC-2 spermatocyte cell line. The results show that all studied compounds affect cell viability, induce apoptosis and cause cellular damage. BPA, BPF and BPS also influence GC-2 cell steroid receptor and steroidogenesis related genes expressions. In addition to specific molecular mechanisms, all studied compounds also increase global DNA methylation. Exposure to a combination of all the studied compounds caused comparable effects on cell culture to each of them examined separately. These data suggest that exposure to BPA and its main substitutes- BPF and BPS induced multitude of effects and hence, BPF and BPS are not safe alternative to BPA in terms of male reproductive health.Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway alterations. The presence of bisphenol A (BPA) in the environment has been confirmed and it is about to be replaced by analogues such as bisphenol F (BPF) and bisphenol S (BPS). Whether the BPF and BPS exert similar adverse effects to BPA has become the subject of intense scientific scrutiny. The aim of the present study was to evaluate and compare the cellular, transcriptomic and methylome effects of exposure to BPA, BPF, BPS individually and in combination on GC-2 spermatocyte cell line. The results show that all studied compounds affect cell viability, induce apoptosis and cause cellular damage. BPA, BPF and BPS also influence GC-2 cell steroid receptor and steroidogenesis related genes expressions. In addition to specific molecular mechanisms, all studied compounds also increase global DNA methylation. Exposure to a combination of all the studied compounds caused comparable effects on cell culture to each of them examined separately. These data suggest that exposure to BPA and its main substitutes- BPF and BPS induced multitude of effects and hence, BPF and BPS are not safe alternative to BPA in terms of male reproductive health. Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway alterations. The presence of bisphenol A (BPA) in the environment has been confirmed and it is about to be replaced by analogues such as bisphenol F (BPF) and bisphenol S (BPS). Whether the BPF and BPS exert similar adverse effects to BPA has become the subject of intense scientific scrutiny. The aim of the present study was to evaluate and compare the cellular, transcriptomic and methylome effects of exposure to BPA, BPF, BPS individually and in combination on GC-2 spermatocyte cell line. The results show that all studied compounds affect cell viability, induce apoptosis and cause cellular damage. BPA, BPF and BPS also influence GC-2 cell steroid receptor and steroidogenesis related genes expressions. In addition to specific molecular mechanisms, all studied compounds also increase global DNA methylation. Exposure to a combination of all the studied compounds caused comparable effects on cell culture to each of them examined separately. These data suggest that exposure to BPA and its main substitutes- BPF and BPS induced multitude of effects and hence, BPF and BPS are not safe alternative to BPA in terms of male reproductive health. •BPA, BPF and BPS affect GC-2 cell viability•ERs and GPR30 cooperate in mediating the effects of BPF and BPS•Mixture of bisphenols causes comparable effects as single compound.•BPA, BPF and BPS affect global DNA methylation.•BPF and BPS are not safe substitutes to BPA. Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway alterations. The presence of bisphenol A (BPA) in the environment has been confirmed and it is about to be replaced by analogues such as bisphenol F (BPF) and bisphenol S (BPS). Whether the BPF and BPS exert similar adverse effects to BPA has become the subject of intense scientific scrutiny. The aim of the present study was to evaluate and compare the cellular, transcriptomic and methylome effects of exposure to BPA, BPF, BPS individually and in combination on GC-2 spermatocyte cell line. The results show that all studied compounds affect cell viability, induce apoptosis and cause cellular damage. BPA, BPF and BPS also influence GC-2 cell steroid receptor and steroidogenesis related genes expressions. In addition to specific molecular mechanisms, all studied compounds also increase global DNA methylation. Exposure to a combination of all the studied compounds caused comparable effects on cell culture to each of them examined separately. These data suggest that exposure to BPA and its main substitutes- BPF and BPS induced multitude of effects and hence, BPF and BPS are not safe alternative to BPA in terms of male reproductive health. |
| Author | Sidorkiewicz, Iwona Zbucka-Krętowska, Monika Jarząbek, Katarzyna Wołczyński, Sławomir Czerniecki, Jan |
| Author_xml | – sequence: 1 givenname: Iwona orcidid: 0000-0003-0254-3095 surname: Sidorkiewicz fullname: Sidorkiewicz, Iwona email: iwona.sidorkiewicz@gmail.com organization: Department of Reproduction and Gynecological Endocrinology, Medical University of Bialystok, M. Sklodowskiej- Curie 24a, 15-276 Bialystok, Poland – sequence: 2 givenname: Jan surname: Czerniecki fullname: Czerniecki, Jan organization: Department of Biology and Pathology of Human Reproduction, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Marii Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland – sequence: 3 givenname: Katarzyna surname: Jarząbek fullname: Jarząbek, Katarzyna organization: Department of Biology and Pathology of Human Reproduction, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Marii Sklodowskiej-Curie 24a, 15-276 Bialystok, Poland – sequence: 4 givenname: Monika surname: Zbucka-Krętowska fullname: Zbucka-Krętowska, Monika organization: Department of Reproduction and Gynecological Endocrinology, Medical University of Bialystok, M. Sklodowskiej- Curie 24a, 15-276 Bialystok, Poland – sequence: 5 givenname: Sławomir surname: Wołczyński fullname: Wołczyński, Sławomir organization: Department of Reproduction and Gynecological Endocrinology, Medical University of Bialystok, M. Sklodowskiej- Curie 24a, 15-276 Bialystok, Poland |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30196065$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kUFv1DAQhS1URLeFP8AB-cihCeM4cRKJS1nRUqkSSIDEzfLaE-FVYgfbqdh_wM_G6baXHnqZubzvzei9M3LivENC3jIoGTDxYV8mpeayAtaV0JcA4gXZMOhFAZzzE7IBqFkB0P06JWcx7gGgr2v2ipxyYL0A0WzIvy2O4zKqcEFTUC7qYOfkJ6upcoZOmH4fRj8hxWFAnSL1A7XO2DtrFjXea7Sfdtahofh39nEJSJOnn75dXuRxtY7v1Ds6-SUijTOGSSWvDwnp9baoqM7n6Zj51-TloMaIbx72Ofl59fnH9ktx-_X6Znt5W2jeiFR0XS2g71s0tWBat8Mg6gE5in6HDVNdK7TWpmYcK95XXdNg0ypjkKtqaFoG_Jy8P_rOwf9ZMCY52bh-oRzmH2WVo-1Zy0Fk6bsH6bKb0Mg52EmFg3xMLwu6o0AHH2PAQWqbVLLe5SztKBnItSi5l2tRci1KQi_h3rt6gj66Pwt9PEKYA7qzGGTUFp1GY0NuRxpvn8P_A7J8rFk |
| CitedBy_id | crossref_primary_10_1016_j_chemosphere_2020_128425 crossref_primary_10_2174_1570159X17666190726112101 crossref_primary_10_1016_j_bcab_2019_101178 crossref_primary_10_1016_j_tox_2021_152780 crossref_primary_10_1016_j_ecoenv_2018_11_106 crossref_primary_10_1016_j_envpol_2019_113228 crossref_primary_10_1002_jat_4170 crossref_primary_10_1016_j_psj_2024_103641 crossref_primary_10_1016_j_taap_2025_117245 crossref_primary_10_1016_j_etap_2021_103751 crossref_primary_10_1016_j_toxlet_2021_06_011 crossref_primary_10_3390_biomedicines10061281 crossref_primary_10_3390_ijms241512188 crossref_primary_10_3390_ijms24097951 crossref_primary_10_1093_toxsci_kfz207 crossref_primary_10_1007_s11356_023_25874_0 crossref_primary_10_1016_j_reprotox_2021_05_011 crossref_primary_10_1002_tox_22983 crossref_primary_10_1016_j_chemosphere_2020_126110 crossref_primary_10_1016_j_reprotox_2024_108656 crossref_primary_10_3724_abbs_2022101 crossref_primary_10_1016_j_afres_2024_100530 crossref_primary_10_1016_j_ecoenv_2021_112366 crossref_primary_10_3390_ijerph17010112 crossref_primary_10_1016_j_earlhumdev_2024_106120 crossref_primary_10_1016_j_eprac_2024_01_006 crossref_primary_10_1186_s12958_020_00596_x crossref_primary_10_1016_j_ecoenv_2023_115391 crossref_primary_10_1016_j_reprotox_2022_06_004 crossref_primary_10_1016_j_scitotenv_2021_150547 |
| Cites_doi | 10.1016/j.reprotox.2007.07.010 10.18632/oncotarget.16923 10.1289/ehp.9357 10.1016/j.mce.2010.01.035 10.1289/ehp.02110s6893 10.1007/s13105-013-0298-8 10.1021/jf400445n 10.1016/j.taap.2015.09.023 10.1074/jbc.M006777200 10.1016/j.chemosphere.2016.05.070 10.1016/j.reprotox.2013.05.013 10.1021/es301334j 10.3892/etm.2016.3569 10.1530/EC-13-0036 10.1093/toxsci/kft271 10.1016/j.reprotox.2010.07.005 10.1016/j.fertnstert.2016.08.021 10.4161/spmg.1.3.18019 10.1289/ehp.0901716 10.1016/j.mce.2012.01.017 10.1016/j.mce.2016.03.024 10.1016/j.intimp.2016.02.030 10.1021/acs.est.5b02135 10.1289/ehp.1103781 10.1016/j.scitotenv.2017.09.194 10.1016/j.envint.2015.09.011 10.1093/humrep/17.11.2839 10.1016/j.fertnstert.2014.11.005 10.1002/iub.370 10.1177/1559325815610582 10.1155/2015/973154 10.3390/ijms130810143 10.1093/humupd/dmk006 10.1289/ehp.10753 10.1002/ijc.25972 10.1016/j.mce.2014.02.002 10.18632/oncotarget.7218 10.1016/j.toxlet.2005.07.001 10.1186/1476-069X-12-26 10.1016/j.taap.2013.05.015 10.1016/j.biopha.2014.09.003 10.1016/j.toxlet.2014.01.035 10.1021/es300876n 10.1210/en.2015-1077 10.1186/gb-2007-8-2-r19 10.1093/toxsci/kfu030 10.1177/0748233717695160 10.1071/RD12159 10.1016/j.steroids.2015.08.011 10.1097/MD.0000000000000211 10.2174/0929867324666171009121001 10.1093/carcin/bgs379 10.1016/j.mce.2009.03.026 10.1016/j.etap.2014.09.014 10.1016/j.mrrev.2011.04.002 10.1093/humupd/dmp048 10.1016/j.taap.2016.11.013 10.3390/ijerph6041472 10.1158/0008-5472.CAN-06-2909 10.1016/j.mrfmmm.2008.02.002 10.1016/j.chemosphere.2017.11.125 10.1016/j.mce.2008.12.018 10.1289/ehp.1408989 10.1016/j.envres.2017.12.011 10.1210/en.2007-1593 10.1590/S0102-311X2002000200005 10.1016/j.etap.2016.11.003 10.1016/j.toxlet.2006.08.012 10.1016/j.tiv.2013.10.024 10.2174/0929867323666160902155434 10.1289/ehp.1409427 10.1038/cddis.2013.203 10.1016/j.jhazmat.2014.12.012 10.1210/jc.2014-4325 10.1177/1933719111398148 10.1016/j.chemosphere.2017.07.004 10.3390/toxics5010005 10.1289/ehp.7534 10.1289/ehp.10587 10.1038/srep09169 |
| ContentType | Journal Article |
| Copyright | 2018 Elsevier Inc. Copyright © 2018 Elsevier Inc. All rights reserved. |
| Copyright_xml | – notice: 2018 Elsevier Inc. – notice: Copyright © 2018 Elsevier Inc. All rights reserved. |
| DBID | AAYXX CITATION NPM 7X8 |
| DOI | 10.1016/j.taap.2018.09.006 |
| DatabaseName | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef PubMed MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic PubMed |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Public Health Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1096-0333 |
| EndPage | 11 |
| ExternalDocumentID | 30196065 10_1016_j_taap_2018_09_006 S0041008X1830406X |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | --- --K --M .~1 0R~ 123 1B1 1RT 1~. 1~5 4.4 457 4G. 5RE 5VS 7-5 71M 8P~ 9JM AABNK AACTN AAEDT AAEDW AAIAV AAIKC AAIKJ AAKOC AALRI AAMNW AAOAW AAQFI AATCM AAXUO ABFRF ABFYP ABJNI ABLST ABMAC ABYKQ ABZDS ACDAQ ACGFO ACGFS ACRLP ADBBV ADEZE AEBSH AEFWE AEKER AENEX AFKWA AFTJW AFXIZ AGHFR AGUBO AGYEJ AHEUO AIEXJ AIKHN AITUG AJOXV AKIFW ALCLG ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ AXJTR BKOJK BLECG BLXMC C45 CS3 DM4 EBS EFBJH EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FIRID FNPLU FYGXN G-Q GBLVA IHE J1W KCYFY KOM LG5 M33 M41 MO0 N9A O-L O9- OAUVE OGGZJ OVD OZT P-8 P-9 P2P PC. Q38 RIG ROL RPZ SDF SDG SDP SES SPCBC SSJ SSP SSZ T5K TEORI TWZ WH7 ZU3 ~G- .55 .GJ .HR 29Q 3O- 53G AAQXK AATTM AAXKI AAYWO AAYXX ABEFU ABFNM ABWVN ABXDB ACRPL ACVFH ADCNI ADFGL ADMUD ADNMO AEIPS AEUPX AFFNX AFJKZ AFPUW AGCQF AGQPQ AGRNS AHHHB AIGII AIIUN AKBMS AKRWK AKYEP ANKPU APXCP ASPBG AVWKF AZFZN BNPGV CAG CITATION COF FEDTE FGOYB G-2 HMT HVGLF HZ~ R2- SEW SPT SSH UHS WUQ X7M XJT XPP Y6R ZGI ZKB ZMT ZXP ~KM NPM 7X8 |
| ID | FETCH-LOGICAL-c356t-88460997ed461cc7ff64fe3e69be51a876cccd413e2392855e57adde3a2f57103 |
| IEDL.DBID | .~1 |
| ISSN | 0041-008X 1096-0333 |
| IngestDate | Fri Jul 11 06:18:23 EDT 2025 Thu Apr 03 07:09:49 EDT 2025 Tue Jul 01 04:18:44 EDT 2025 Thu Apr 24 23:13:16 EDT 2025 Fri Feb 23 02:29:41 EST 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Language | English |
| License | Copyright © 2018 Elsevier Inc. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c356t-88460997ed461cc7ff64fe3e69be51a876cccd413e2392855e57adde3a2f57103 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0003-0254-3095 |
| PMID | 30196065 |
| PQID | 2101917306 |
| PQPubID | 23479 |
| PageCount | 11 |
| ParticipantIDs | proquest_miscellaneous_2101917306 pubmed_primary_30196065 crossref_citationtrail_10_1016_j_taap_2018_09_006 crossref_primary_10_1016_j_taap_2018_09_006 elsevier_sciencedirect_doi_10_1016_j_taap_2018_09_006 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2018-11-15 |
| PublicationDateYYYYMMDD | 2018-11-15 |
| PublicationDate_xml | – month: 11 year: 2018 text: 2018-11-15 day: 15 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Toxicology and applied pharmacology |
| PublicationTitleAlternate | Toxicol Appl Pharmacol |
| PublicationYear | 2018 |
| Publisher | Elsevier Inc |
| Publisher_xml | – name: Elsevier Inc |
| References | Rajender, Avery, Agarwal (bb0280) 2011; 727 Bloom, Mok-Lin, Fujimoto (bb0030) 2016; 106 Dumasia, Kumar, Deshpande, Sonawane, Balasinor (bb5005) 2016; 428 Li, Wang, Zhang, Niu, Yao, Liu (bb0195) 2015; 10 Lan, Wu, Lin, Yang, Chang, Hu (bb0185) 2017; 185 Usman, Ahmad (bb0370) 2016; 158 Tiwari, Vanage (bb0355) 2013; 40 Yin, Dai, Cui, Jiang, Liu, Han, Lin, Cao, Liu (bb0425) 2017; 314 Acconcia, Pallottini, Marino (bb0010) 2015; 13 Marques-Pinto, Carvalho (bb0225) 2013; 2 Kolesnikova, Kolesnikov, Kurashova, Bairova (bb0170) 2015 Rochester, Bolden (bb0295) 2015; 123 Şenyildiz (bb0310) 2015 Viñas, Watson (bb0385) 2013; 12 Gámez, Penalba, Cardoso, Ponzo, Carbone, Pandolfi, Scacchi, Reynoso (bb0130) 2014; 70 Takayanagi, Tokunaga, Liu, Okada, Matsushima, Shimohigashi (bb0345) 2006; 167 Thayer, Taylor, Garantziotis, Schurman, Kissling, Hunt, Herbert, Church, Jankowich, Churchwell, Scheri, Birnbaum, Bucher (bb0350) 2015; 124 Kortenkamp (bb0180) 2007; 115 Ribeiro, Ladeira, Viegas (bb0290) 2017; 5 Ye, Wong, Kramer, Zhou, Jia, Calafat (bb0410) 2015; 49 Xue, Kannan, Kumosani, Al-Malki, Kannan (bb0405) 2018; 162 Wu, Zhang, Wang, Gao, Chen, Palumbo, Guo, Zeng (bb0395) 2018; 615 Zhang, Zhang, Feng, Li, Huynh, Sun, Sun, Shen (bb0430) 2013; 25 Farhi, Ben-Haroush (bb0110) 2011; 13 Yin, Dai, Jiang, Liu, Chen, Han, Cao, Liu (bb0420) 2016; 48 Qu, Liu, Huang, Xu, Du, Gu, Wang (bb0270) 2014; 28 Metz (bb0235) 2016 Prossnitz, Maggiolini (bb0260) 2009; 308 Qiu, Shao, Lei, Zheng, Qiu, Yang, Zheng (bb0265) 2018; 194 Molina-Molina, Amaya, Grimaldi, Sáenz, Real, Fernández, Balaguer, Olea (bb0240) 2013; 272 Culty, Liu, Manku, Chan, Papadopoulos (bb0095) 2015; 103 Gao, Yang, Li, Feng, Shi, Zhao, Liu (bb0135) 2015; 94 Zhang, Chen, Chen, Qiu, Zheng, Li, Yang, Wen (bb0435) 2014; 68 Andra, Charisiadis, Arora, van Vliet-Ostaptchouk, Makris (bb0020) 2015; 85 Sidorkiewicz, Zaręba, Wołczyński, Czerniecki (bb0320) 2017; 33 Campion, Catlin, Heger, McDonnell, Pacheco, Saffarini, Sandrof, Boekelheide (bb0050) 2012; 101 Rahman, Kwon, Lee, Yoon, Ryu, Pang (bb0275) 2015; 5 Sirianni, Chimento, Ruggiero, De Luca, Lappano, Andò, Maggiolini, Pezzi (bb0335) 2008; 149 Katchy, Pinto, Jonsson, Nguyen-Vu, Pandelova, Riu, Schramm, Samarov, Gustafsson, Bondesson, Williams (bb0160) 2014; 138 Futran Fuhrman, Tal, Arnon (bb0125) 2015; 286 Bennetts, De Iuliis, Nixon, Kime, Zelski, McVicar, Lewis, Aitken (bb0025) 2008; 641 Routledge, White, Parker, Sumpter (bb0305) 2000; 275 Cooper, Noonan, von Eckardstein, Auger, Baker, Behre, Haugen, Kruger, Wang, Mbizvo, Vogelsong (bb0085) 2010; 16 Ozden, Turgut Kara, Sezerman, Durasi, Chen, Demirel, Alpertunga, Chipman, Mally (bb0250) 2015; 289 Lee, Hwang, Park, Yi, Jeung, Choi (bb0190) 2012; 29 Prossnitz, Barton (bb0255) 2014; 389 Wang, Zhang, Li, Zhang, Deng, Lian, Jia, Li, Zheng, Ding, Yang, Ma, Wang, Zhang, Guo Wen (bb0390) 2017; 8 Chimento, Sirianni, Delalande, Silandre, Bois, Andò, Maggiolini, Carreau, Pezzi (bb0070) 2010; 320 Ge, Chen, Liu, Zhang, Liu, Huang, Zhang, Wong, Giesy, Du, Wang (bb0140) 2014; 226 Hauser, Skakkebaek, Hass, Toppari, Juul, Andersson, Kortenkamp, Heindel, Trasande (bb0145) 2015; 100 Albanito, Madeo, Lappano, Vivacqua, Rago, Carpino, Oprea, Prossnitz, Musti, Andò, Maggiolini (bb0015) 2007; 67 Liao, Liu, Kannan (bb0210) 2012; 46 Manfo, Jubendradass, Nantia, Moundipa, Mathur (bb0220) 2014; 228 Feron, Cassee, Groten, van Vliet, van Zorge (bb0115) 2002; 110 Chevalier, Bouskine, Fenichel (bb0055) 2012; 130 Singh, Li (bb0330) 2012; 13 Bolli, Bulzomi, Galluzzo, Acconcia, Marino (bb0035) 2010; 62 Liao, Kannan (bb0200) 2013; 61 Okada, Tokunaga, Liu, Takayanagi, Matsushima, Shimohigashi (bb0245) 2008; 116 Trasler (bb0365) 2009; 306 Chianese, Troisi, Richards, Scafuro, Fasano, Guida, Pierantoni, Meccariello (bb0065) 2018; 25 Vandenberg, Hauser, Marcus, Olea, Welshons (bb0375) 2007; 24 Xie, Bu, Li, Lan, Wu, Yuan, Wang (bb0400) 2016; 7 Abdel-Maksoud, Leasor, Butzen, Braden, Akingbemi (bb0005) 2015; 156 Danzl, Sei, Soda, Ike, Fujita (bb5000) 2009; 6 Rosenmai, Dybdahl, Pedersen, Alice Van Vugt-Lussenburg, Wedebye, Taxvig, Vinggaard (bb0300) 2014; 139 Svajger, Dolenc, Jeras (bb0340) 2016; 34 Chouhan, Yadav, Prakash, Westfall, Ghosh, Agarwal, Singh (bb0080) 2015; 39 Kim, Jung, An, Hwang, Vo, Kim, Lee, Choi, Jeung (bb0165) 2012; 63 Rajpert-De Meyts (bb0285) 2006; 12 Fotakis, Timbrell (bb0120) 2006; 160 Meeker, Ehrlich, Toth, Wright, Calafat, Trisini, Ye, Hauser (bb0230) 2010; 30 Chimento, Sirianni, Casaburi, Ruggiero, Maggiolini, Andò, Pezzi (bb0075) 2012; 355 Komarowska, Hermanowicz, Czyzewska, Milewski, Matuszczak, Miltyk, Debek (bb0175) 2015; 2015 Dairkee, Luciani-Torres, Moore, Goodson (bb0100) 2013; 34 Liao, Liu, Alomirah, Loi, Mohd, Moon, Nakata, Kannan (bb0205) 2012; 46 Cui, Jing, Wu, Yan, Li, Shen, Wang (bb0090) 2016; 12 Eladak, Grisin, Moison, Guerquin, N'Tumba-Byn, Pozzi-Gaudin, Benachi, Livera, Rouiller-Fabre, Habert (bb0105) 2015; 103 Yeung, Wan, Law, Wong (bb0415) 2011; 1 Calafat, Kuklenyik, Reidy, Caudill, Ekong, Needham (bb0040) 2005; 113 Liu, Duan, Li, Xu, Zhang, Chen, He, Lu, Wu, Pi, Luo, Zhang, Zhong, Yu, Zhou (bb0215) 2013; 4 Vandenberg, Chahoud, Heindel, Padmanabhan, Paumgartten, Schoenfelder (bb0380) 2010; 118 Hellemans, Mortier, De Paepe, Speleman, Vandesompele (bb0150) 2007; 8 Chianese, Cobellis, Chioccarelli, Ciaramella, Migliaccio, Fasano, Pierantoni, Meccariello (bb0060) 2016; 23 Singh, Jaiswal (bb0325) 2011; 18 Sheng, Zhu (bb0315) 2011; 119 Toppari, Haavisto, Alanen (bb0360) 2002; 18 Calafat, Ye, Wong, Reidy, Needham (bb0045) 2008; 116 Ikezuki, Tsutsumi, Takai, Kamei, Taketani (bb0155) 2002; 17 Rosenmai (10.1016/j.taap.2018.09.006_bb0300) 2014; 139 Wu (10.1016/j.taap.2018.09.006_bb0395) 2018; 615 Rahman (10.1016/j.taap.2018.09.006_bb0275) 2015; 5 Hellemans (10.1016/j.taap.2018.09.006_bb0150) 2007; 8 Qu (10.1016/j.taap.2018.09.006_bb0270) 2014; 28 Routledge (10.1016/j.taap.2018.09.006_bb0305) 2000; 275 Bennetts (10.1016/j.taap.2018.09.006_bb0025) 2008; 641 Kolesnikova (10.1016/j.taap.2018.09.006_bb0170) 2015 Tiwari (10.1016/j.taap.2018.09.006_bb0355) 2013; 40 Sirianni (10.1016/j.taap.2018.09.006_bb0335) 2008; 149 Eladak (10.1016/j.taap.2018.09.006_bb0105) 2015; 103 Bolli (10.1016/j.taap.2018.09.006_bb0035) 2010; 62 Bloom (10.1016/j.taap.2018.09.006_bb0030) 2016; 106 Abdel-Maksoud (10.1016/j.taap.2018.09.006_bb0005) 2015; 156 Acconcia (10.1016/j.taap.2018.09.006_bb0010) 2015; 13 Dairkee (10.1016/j.taap.2018.09.006_bb0100) 2013; 34 Lee (10.1016/j.taap.2018.09.006_bb0190) 2012; 29 Thayer (10.1016/j.taap.2018.09.006_bb0350) 2015; 124 Liao (10.1016/j.taap.2018.09.006_bb0200) 2013; 61 Viñas (10.1016/j.taap.2018.09.006_bb0385) 2013; 12 Zhang (10.1016/j.taap.2018.09.006_bb0435) 2014; 68 Chouhan (10.1016/j.taap.2018.09.006_bb0080) 2015; 39 Gao (10.1016/j.taap.2018.09.006_bb0135) 2015; 94 Şenyildiz (10.1016/j.taap.2018.09.006_bb0310) 2015 Campion (10.1016/j.taap.2018.09.006_bb0050) 2012; 101 Kim (10.1016/j.taap.2018.09.006_bb0165) 2012; 63 Sidorkiewicz (10.1016/j.taap.2018.09.006_bb0320) 2017; 33 Andra (10.1016/j.taap.2018.09.006_bb0020) 2015; 85 Calafat (10.1016/j.taap.2018.09.006_bb0040) 2005; 113 Dumasia (10.1016/j.taap.2018.09.006_bb5005) 2016; 428 Takayanagi (10.1016/j.taap.2018.09.006_bb0345) 2006; 167 Yin (10.1016/j.taap.2018.09.006_bb0420) 2016; 48 Danzl (10.1016/j.taap.2018.09.006_bb5000) 2009; 6 Ye (10.1016/j.taap.2018.09.006_bb0410) 2015; 49 Yin (10.1016/j.taap.2018.09.006_bb0425) 2017; 314 Hauser (10.1016/j.taap.2018.09.006_bb0145) 2015; 100 Sheng (10.1016/j.taap.2018.09.006_bb0315) 2011; 119 Farhi (10.1016/j.taap.2018.09.006_bb0110) 2011; 13 Trasler (10.1016/j.taap.2018.09.006_bb0365) 2009; 306 Ge (10.1016/j.taap.2018.09.006_bb0140) 2014; 226 Rajender (10.1016/j.taap.2018.09.006_bb0280) 2011; 727 Wang (10.1016/j.taap.2018.09.006_bb0390) 2017; 8 Chianese (10.1016/j.taap.2018.09.006_bb0060) 2016; 23 Chimento (10.1016/j.taap.2018.09.006_bb0070) 2010; 320 Katchy (10.1016/j.taap.2018.09.006_bb0160) 2014; 138 Toppari (10.1016/j.taap.2018.09.006_bb0360) 2002; 18 Usman (10.1016/j.taap.2018.09.006_bb0370) 2016; 158 Xie (10.1016/j.taap.2018.09.006_bb0400) 2016; 7 Vandenberg (10.1016/j.taap.2018.09.006_bb0375) 2007; 24 Prossnitz (10.1016/j.taap.2018.09.006_bb0260) 2009; 308 Ikezuki (10.1016/j.taap.2018.09.006_bb0155) 2002; 17 Meeker (10.1016/j.taap.2018.09.006_bb0230) 2010; 30 Yeung (10.1016/j.taap.2018.09.006_bb0415) 2011; 1 Chianese (10.1016/j.taap.2018.09.006_bb0065) 2018; 25 Singh (10.1016/j.taap.2018.09.006_bb0325) 2011; 18 Metz (10.1016/j.taap.2018.09.006_bb0235) 2016 Albanito (10.1016/j.taap.2018.09.006_bb0015) 2007; 67 Calafat (10.1016/j.taap.2018.09.006_bb0045) 2008; 116 Cooper (10.1016/j.taap.2018.09.006_bb0085) 2010; 16 Chimento (10.1016/j.taap.2018.09.006_bb0075) 2012; 355 Vandenberg (10.1016/j.taap.2018.09.006_bb0380) 2010; 118 Zhang (10.1016/j.taap.2018.09.006_bb0430) 2013; 25 Rajpert-De Meyts (10.1016/j.taap.2018.09.006_bb0285) 2006; 12 Liao (10.1016/j.taap.2018.09.006_bb0205) 2012; 46 Rochester (10.1016/j.taap.2018.09.006_bb0295) 2015; 123 Gámez (10.1016/j.taap.2018.09.006_bb0130) 2014; 70 Li (10.1016/j.taap.2018.09.006_bb0195) 2015; 10 Futran Fuhrman (10.1016/j.taap.2018.09.006_bb0125) 2015; 286 Kortenkamp (10.1016/j.taap.2018.09.006_bb0180) 2007; 115 Manfo (10.1016/j.taap.2018.09.006_bb0220) 2014; 228 Culty (10.1016/j.taap.2018.09.006_bb0095) 2015; 103 Ozden (10.1016/j.taap.2018.09.006_bb0250) 2015; 289 Komarowska (10.1016/j.taap.2018.09.006_bb0175) 2015; 2015 Xue (10.1016/j.taap.2018.09.006_bb0405) 2018; 162 Singh (10.1016/j.taap.2018.09.006_bb0330) 2012; 13 Feron (10.1016/j.taap.2018.09.006_bb0115) 2002; 110 Okada (10.1016/j.taap.2018.09.006_bb0245) 2008; 116 Liao (10.1016/j.taap.2018.09.006_bb0210) 2012; 46 Cui (10.1016/j.taap.2018.09.006_bb0090) 2016; 12 Qiu (10.1016/j.taap.2018.09.006_bb0265) 2018; 194 Marques-Pinto (10.1016/j.taap.2018.09.006_bb0225) 2013; 2 Chevalier (10.1016/j.taap.2018.09.006_bb0055) 2012; 130 Lan (10.1016/j.taap.2018.09.006_bb0185) 2017; 185 Fotakis (10.1016/j.taap.2018.09.006_bb0120) 2006; 160 Prossnitz (10.1016/j.taap.2018.09.006_bb0255) 2014; 389 Svajger (10.1016/j.taap.2018.09.006_bb0340) 2016; 34 Liu (10.1016/j.taap.2018.09.006_bb0215) 2013; 4 Molina-Molina (10.1016/j.taap.2018.09.006_bb0240) 2013; 272 Ribeiro (10.1016/j.taap.2018.09.006_bb0290) 2017; 5 |
| References_xml | – volume: 106 start-page: 857 year: 2016 end-page: 863 ident: bb0030 article-title: Bisphenol a and ovarian steroidogenesis publication-title: Fertil. Steril. – volume: 100 start-page: 1267 year: 2015 end-page: 1277 ident: bb0145 article-title: Male reproductive disorders, diseases, and costs of exposure to endocrine-disrupting chemicals in the European Union publication-title: J. Clin. Endocrinol. Metab. – volume: 7 start-page: 10606 year: 2016 end-page: 10615 ident: bb0400 article-title: Neonatal bisphenol a exposure induces meiotic arrest and apoptosis of spermatogenic cells publication-title: Oncotarget – volume: 641 start-page: 1 year: 2008 end-page: 11 ident: bb0025 article-title: Impact of estrogenic compounds on DNA integrity in human spermatozoa: evidence for cross-linking and redox cycling activities publication-title: Mutat. Res. – volume: 115 start-page: 98 year: 2007 end-page: 105 ident: bb0180 article-title: Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals publication-title: Environ. Health Perspect. – volume: 1 start-page: 231 year: 2011 end-page: 239 ident: bb0415 article-title: Endocrine disrupting chemicals: multiple effects on testicular signaling and spermatogenesis publication-title: Spermatogenesis – volume: 308 start-page: 32 year: 2009 end-page: 38 ident: bb0260 article-title: Mechanisms of estrogen signaling and gene expression via GPR30 publication-title: Mol. Cell. Endocrinol. – volume: 389 start-page: 71 year: 2014 end-page: 83 ident: bb0255 article-title: Estrogen biology: new insights into GPER function and clinical opportunities publication-title: Mol. Cell. Endocrinol. – volume: 13 year: 2015 ident: bb0010 article-title: Molecular mechanisms of action of BPA publication-title: Dose Response – volume: 124 start-page: 437 year: 2015 end-page: 444 ident: bb0350 article-title: Bisphenol A, bisphenol S, and 4-hydroxyphenyl 4-isoprooxyphenylsulfone (BPSIP) in urine and blood of cashiers publication-title: Environ. Health Perspect. – volume: 615 start-page: 87 year: 2018 end-page: 98 ident: bb0395 article-title: Occurrence of bisphenol S in the environment and implications for human exposure: a short review publication-title: Sci. Total Environ. – volume: 63 start-page: 445 year: 2012 end-page: 455 ident: bb0165 article-title: Additional effects of bisphenol A and paraben on the induction of calbindin-D(9K) and progesterone receptor via an estrogen receptor pathway in rat pituitary GH3 cells publication-title: J. Physiol. Pharmacol. – volume: 18 start-page: 418 year: 2011 end-page: 425 ident: bb0325 article-title: Human male infertility: a complex multifactorial phenotype publication-title: Reprod. Sci. – volume: 34 start-page: 146 year: 2016 end-page: 154 ident: bb0340 article-title: In vitro impact of bisphenols BPA, BPF, BPAF and 17beta-estradiol (E2) on human monocyte-derived dendritic cell generation, maturation and function publication-title: Int. Immunopharmacol. – volume: 94 year: 2015 ident: bb0135 article-title: Bisphenol A and hormone-associated cancers: current progress and perspectives publication-title: Medicine (Baltimore) – volume: 46 start-page: 6515 year: 2012 end-page: 6522 ident: bb0210 article-title: Bisphenol s, a new bisphenol analogue, in paper products and currency bills and its association with bisphenol a residues publication-title: Environ Sci Technol – volume: 13 start-page: 10143 year: 2012 end-page: 10153 ident: bb0330 article-title: Epigenetic effects of environmental chemicals bisphenol A and phthalates publication-title: Int. J. Mol. Sci. – start-page: 579 year: 2015 end-page: 584 ident: bb0170 article-title: Causes and Factors of Male Infertility. Vestnik Rossiiskoi akademii meditsinskikh nauk/Rossiiskaia akademiia meditsinskikh nauk – volume: 25 start-page: 847 year: 2013 end-page: 859 ident: bb0430 article-title: Exposure to bisphenol A results in a decline in mouse spermatogenesis publication-title: Reprod. Fertil. Dev. – volume: 162 start-page: 35 year: 2018 end-page: 40 ident: bb0405 article-title: Resin-based dental sealants as a source of human exposure to bisphenol analogues, bisphenol A diglycidyl ether, and its derivatives publication-title: Environ. Res. – volume: 314 start-page: 98 year: 2017 end-page: 108 ident: bb0425 article-title: The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2α/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity publication-title: Toxicol. Appl. Pharmacol. – volume: 727 start-page: 62 year: 2011 end-page: 71 ident: bb0280 article-title: Epigenetics, spermatogenesis and male infertility publication-title: Mutat. Res. – volume: 320 start-page: 136 year: 2010 end-page: 144 ident: bb0070 article-title: 17 beta-estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ER alpha publication-title: Mol. Cell. Endocrinol. – volume: 46 start-page: 6860 year: 2012 end-page: 6866 ident: bb0205 article-title: Bisphenol S in urine from the United States and seven Asian countries: occurrence and human exposures publication-title: Environ Sci Technol – volume: 10 year: 2015 ident: bb0195 article-title: The molecular mechanism of bisphenol A (BPA) as an endocrine disruptor by interacting with nuclear receptors: insights from molecular dynamics (MD) simulations publication-title: PLoS One – volume: 5 start-page: 9169 year: 2015 ident: bb0275 article-title: Bisphenol-A affects male fertility via fertility-related proteins in spermatozoa publication-title: Sci. Rep. – volume: 5 year: 2017 ident: bb0290 article-title: EDCs Mixtures: a Stealthy Hazard for Human Health? publication-title: Toxics – start-page: 28 year: 2016 end-page: 36 ident: bb0235 article-title: Bisphenol a: Understanding the Controversy. Workplace Health & Safety 64 – volume: 289 start-page: 203 year: 2015 end-page: 212 ident: bb0250 article-title: Assessment of global and gene-specific DNA methylation in rat liver and kidney in response to non-genotoxic carcinogen exposure publication-title: Toxicol. Appl. Pharmacol. – volume: 30 start-page: 532 year: 2010 end-page: 539 ident: bb0230 article-title: Semen quality and sperm DNA damage in relation to urinary bisphenol a among men from an infertility clinic publication-title: Reprod. Toxicol. – volume: 24 start-page: 139 year: 2007 end-page: 177 ident: bb0375 article-title: Human exposure to bisphenol A (BPA) publication-title: Reprod. Toxicol. – volume: 103 start-page: 105 year: 2015 end-page: 114 ident: bb0095 article-title: Expression of steroidogenesis-related genes in murine male germ cells publication-title: Steroids – volume: 70 start-page: 239 year: 2014 end-page: 246 ident: bb0130 article-title: Low dose of bisphenol A impairs the reproductive axis of prepuberal male rats publication-title: J. Physiol. Biochem. – volume: 2 start-page: R15 year: 2013 end-page: R29 ident: bb0225 article-title: Human infertility: are endocrine disruptors to blame? publication-title: Endocr Connect – volume: 68 start-page: 1037 year: 2014 end-page: 1043 ident: bb0435 article-title: Bisphenol A stimulates human lung cancer cell migration via upregulation of matrix metalloproteinases by GPER/EGFR/ERK1/2 signal pathway publication-title: Biomed Pharmacother – volume: 116 start-page: 32 year: 2008 end-page: 38 ident: bb0245 article-title: Direct evidence revealing structural elements essential for the high binding ability of bisphenol a to human estrogen-related receptor-gamma publication-title: Environ. Health Perspect. – volume: 167 start-page: 95 year: 2006 end-page: 105 ident: bb0345 article-title: Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity publication-title: Toxicol. Lett. – volume: 48 start-page: 265 year: 2016 end-page: 271 ident: bb0420 article-title: Role of DNA methylation in bisphenol A exposed mouse spermatocyte publication-title: Environ. Toxicol. Pharmacol. – volume: 101 start-page: 315 year: 2012 end-page: 360 ident: bb0050 article-title: Male reprotoxicity and endocrine disruption publication-title: EXS – volume: 130 start-page: 241 year: 2012 end-page: 242 ident: bb0055 article-title: Bisphenol A promotes testicular seminoma cell proliferation through GPER/GPR30 publication-title: Int. J. Cancer – volume: 226 start-page: 81 year: 2014 end-page: 89 ident: bb0140 article-title: Involvement of activating ERK1/2 through G protein coupled receptor 30 and estrogen receptor α/β in low doses of bisphenol A promoting growth of Sertoli TM4 cells publication-title: Toxicol. Lett. – volume: 8 start-page: R19 year: 2007 ident: bb0150 article-title: qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data publication-title: Genome Biol. – volume: 33 start-page: 601 year: 2017 end-page: 609 ident: bb0320 article-title: Endocrine-disrupting chemicals-Mechanisms of action on male reproductive system publication-title: Toxicol. Ind. Health – volume: 39 start-page: 405 year: 2015 end-page: 416 ident: bb0080 article-title: Increase in the expression of inducible nitric oxide synthase on exposure to bisphenol a: a possible cause for decline in steroidogenesis in male mice publication-title: Environ. Toxicol. Pharmacol. – volume: 13 start-page: 51 year: 2011 end-page: 54 ident: bb0110 article-title: Distribution of causes of infertility in patients attending primary fertility clinics in Israel publication-title: Isr. Med. Assoc. J. – volume: 149 start-page: 5043 year: 2008 end-page: 5051 ident: bb0335 article-title: The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line publication-title: Endocrinology – volume: 113 start-page: 391 year: 2005 end-page: 395 ident: bb0040 article-title: Urinary concentrations of bisphenol a and 4-nonylphenol in a human reference population publication-title: Environ. Health Perspect. – volume: 85 start-page: 352 year: 2015 end-page: 379 ident: bb0020 article-title: Biomonitoring of human exposures to chlorinated derivatives and structural analogs of bisphenol A publication-title: Environ. Int. – volume: 116 start-page: 39 year: 2008 end-page: 44 ident: bb0045 article-title: Exposure of the U.S. population to bisphenol a and 4-tertiary-octylphenol: 2003-2004 publication-title: Environ. Health Perspect. – volume: 40 start-page: 60 year: 2013 end-page: 68 ident: bb0355 article-title: Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility publication-title: Reprod. Toxicol. – volume: 12 start-page: 1973 year: 2016 end-page: 1979 ident: bb0090 article-title: DNA methylation in spermatogenesis and male infertility publication-title: Exp Ther Med – volume: 158 start-page: 131 year: 2016 end-page: 142 ident: bb0370 article-title: From BPA to its analogues: is it a safe journey? publication-title: Chemosphere – volume: 103 start-page: 11 year: 2015 end-page: 21 ident: bb0105 article-title: A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound publication-title: Fertil. Steril. – volume: 4 start-page: e676 year: 2013 ident: bb0215 article-title: Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity publication-title: Cell Death Dis. – volume: 138 start-page: 21 year: 2014 end-page: 35 ident: bb0160 article-title: Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner publication-title: Toxicol. Sci. – volume: 12 start-page: 303 year: 2006 end-page: 323 ident: bb0285 article-title: Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects publication-title: Hum. Reprod. Update – volume: 62 start-page: 684 year: 2010 end-page: 687 ident: bb0035 article-title: Bisphenol a impairs estradiol-induced protective effects against DLD-1 colon cancer cell growth publication-title: IUBMB Life – volume: 2015 year: 2015 ident: bb0175 article-title: Serum bisphenol A level in boys with cryptorchidism: a step to male infertility? publication-title: Int. J. Endocrinol. – volume: 139 start-page: 35 year: 2014 end-page: 47 ident: bb0300 article-title: Are structural analogues to bisphenol a safe alternatives? publication-title: Toxicol. Sci. – volume: 29 start-page: 883 year: 2012 end-page: 890 ident: bb0190 article-title: Treatment with bisphenol A and methoxychlor results in the growth of human breast cancer cells and alteration of the expression of cell cycle-related genes, cyclin D1 and p21, via an estrogen receptor-dependent signaling pathway publication-title: Int. J. Mol. Med. – volume: 23 start-page: 4070 year: 2016 end-page: 4091 ident: bb0060 article-title: Kisspeptins, Estrogens and Male Fertility publication-title: Curr. Med. Chem. – volume: 119 start-page: 1775 year: 2011 end-page: 1780 ident: bb0315 article-title: Low concentrations of bisphenol A induce mouse spermatogonial cell proliferation by G protein-coupled receptor 30 and estrogen receptor-α publication-title: Environ. Health Perspect. – volume: 25 start-page: 748 year: 2018 end-page: 770 ident: bb0065 article-title: Bisphenol A in reproduction: epigenetic effects publication-title: Curr. Med. Chem. – volume: 17 start-page: 2839 year: 2002 end-page: 2841 ident: bb0155 article-title: Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure publication-title: Hum. Reprod. – volume: 228 start-page: 57 year: 2014 end-page: 82 ident: bb0220 article-title: Adverse effects of bisphenol A on male reproductive function publication-title: Rev. Environ. Contam. Toxicol. – volume: 428 start-page: 89 year: 2016 end-page: 100 ident: bb5005 article-title: Differential roles of estrogen receptors, ESR1 and ESR2, in adult rat spermatogenesis publication-title: Mol. Cell Endocrinol. – volume: 18 start-page: 413 year: 2002 end-page: 420 ident: bb0360 article-title: Changes in male reproductive health and effects of endocrine disruptors in Scandinavian countries publication-title: Cad Saude Publica – volume: 110 start-page: 893 year: 2002 end-page: 899 ident: bb0115 article-title: International issues on human health effects of exposure to chemical mixtures publication-title: Environ. Health Perspect. – volume: 12 start-page: 26 year: 2013 ident: bb0385 article-title: Mixtures of xenoestrogens disrupt estradiol-induced non-genomic signaling and downstream functions in pituitary cells publication-title: Environ. Health – volume: 49 start-page: 11834 year: 2015 end-page: 11839 ident: bb0410 article-title: Urinary concentrations of bisphenol A and three other bisphenols in convenience samples of U.S. adults during 2000-2014 publication-title: Environ Sci Technol – volume: 34 start-page: 703 year: 2013 end-page: 712 ident: bb0100 article-title: Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells publication-title: Carcinogenesis – volume: 61 start-page: 4655 year: 2013 end-page: 4662 ident: bb0200 article-title: Concentrations and profiles of bisphenol A and other bisphenol analogues in foodstuffs from the United States and their implications for human exposure publication-title: J. Agric. Food Chem. – volume: 355 start-page: 49 year: 2012 end-page: 59 ident: bb0075 article-title: 17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line publication-title: Mol. Cell. Endocrinol. – volume: 286 start-page: 589 year: 2015 end-page: 611 ident: bb0125 article-title: Why endocrine disrupting chemicals (EDCs) challenge traditional risk assessment and how to respond publication-title: J. Hazard. Mater. – volume: 185 start-page: 237 year: 2017 end-page: 246 ident: bb0185 article-title: Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cells publication-title: Chemosphere – volume: 16 start-page: 231 year: 2010 end-page: 245 ident: bb0085 article-title: World Health Organization reference values for human semen characteristics publication-title: Hum. Reprod. Update – volume: 28 start-page: 373 year: 2014 end-page: 380 ident: bb0270 article-title: Estrogen receptors are involved in polychlorinated biphenyl-induced apoptosis on mouse spermatocyte GC-2 cell line publication-title: Toxicol. in Vitro – volume: 156 start-page: 4672 year: 2015 end-page: 4683 ident: bb0005 article-title: Prenatal exposures of male rats to the environmental chemicals bisphenol a and Di(2-Ethylhexyl) phthalate impact the sexual differentiation process publication-title: Endocrinology – volume: 6 start-page: 1472 year: 2009 end-page: 1484 ident: bb5000 article-title: Biodegradation of bisphenol A, bisphenol F and bisphenol S in seawater publication-title: Int. J. Environ. Res. Public Health – volume: 123 start-page: 643 year: 2015 end-page: 650 ident: bb0295 article-title: Bisphenol S and F: a Systematic Review and Comparison of the Hormonal activity of Bisphenol A Substitutes publication-title: Environ. Health Perspect. – volume: 275 start-page: 35986 year: 2000 end-page: 35993 ident: bb0305 article-title: Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta publication-title: J. Biol. Chem. – volume: 8 start-page: 49005 year: 2017 end-page: 49015 ident: bb0390 article-title: Low concentration of BPA induces mice spermatocytes apoptosis via GPR30 publication-title: Oncotarget – volume: 160 start-page: 171 year: 2006 end-page: 177 ident: bb0120 article-title: In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride publication-title: Toxicol. Lett. – volume: 306 start-page: 33 year: 2009 end-page: 36 ident: bb0365 article-title: Epigenetics in spermatogenesis publication-title: Mol. Cell. Endocrinol. – volume: 118 start-page: 1055 year: 2010 end-page: 1070 ident: bb0380 article-title: Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A publication-title: Environ. Health Perspect. – volume: 272 start-page: 127 year: 2013 end-page: 136 ident: bb0240 article-title: In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-a congeners and derivatives via nuclear receptors publication-title: Toxicol. Appl. Pharmacol. – start-page: 153 year: 2015 end-page: 164 ident: bb0310 article-title: Alteration in global DNA methylation after bisphenol a exposure in MCF-7 cells publication-title: J. Fac. Pharm. Istanbul – volume: 194 start-page: 1 year: 2018 end-page: 8 ident: bb0265 article-title: Immunotoxicity of bisphenol S and F are similar to that of bisphenol A during zebrafish early development publication-title: Chemosphere – volume: 67 start-page: 1859 year: 2007 end-page: 1866 ident: bb0015 article-title: G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells publication-title: Cancer Res. – volume: 24 start-page: 139 year: 2007 ident: 10.1016/j.taap.2018.09.006_bb0375 article-title: Human exposure to bisphenol A (BPA) publication-title: Reprod. Toxicol. doi: 10.1016/j.reprotox.2007.07.010 – volume: 8 start-page: 49005 year: 2017 ident: 10.1016/j.taap.2018.09.006_bb0390 article-title: Low concentration of BPA induces mice spermatocytes apoptosis via GPR30 publication-title: Oncotarget doi: 10.18632/oncotarget.16923 – volume: 63 start-page: 445 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0165 article-title: Additional effects of bisphenol A and paraben on the induction of calbindin-D(9K) and progesterone receptor via an estrogen receptor pathway in rat pituitary GH3 cells publication-title: J. Physiol. Pharmacol. – volume: 115 start-page: 98 issue: Suppl. 1 year: 2007 ident: 10.1016/j.taap.2018.09.006_bb0180 article-title: Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals publication-title: Environ. Health Perspect. doi: 10.1289/ehp.9357 – volume: 320 start-page: 136 year: 2010 ident: 10.1016/j.taap.2018.09.006_bb0070 article-title: 17 beta-estradiol activates rapid signaling pathways involved in rat pachytene spermatocytes apoptosis through GPR30 and ER alpha publication-title: Mol. Cell. Endocrinol. doi: 10.1016/j.mce.2010.01.035 – volume: 110 start-page: 893 issue: Suppl. 6 year: 2002 ident: 10.1016/j.taap.2018.09.006_bb0115 article-title: International issues on human health effects of exposure to chemical mixtures publication-title: Environ. Health Perspect. doi: 10.1289/ehp.02110s6893 – volume: 70 start-page: 239 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0130 article-title: Low dose of bisphenol A impairs the reproductive axis of prepuberal male rats publication-title: J. Physiol. Biochem. doi: 10.1007/s13105-013-0298-8 – volume: 61 start-page: 4655 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0200 article-title: Concentrations and profiles of bisphenol A and other bisphenol analogues in foodstuffs from the United States and their implications for human exposure publication-title: J. Agric. Food Chem. doi: 10.1021/jf400445n – volume: 289 start-page: 203 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0250 article-title: Assessment of global and gene-specific DNA methylation in rat liver and kidney in response to non-genotoxic carcinogen exposure publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2015.09.023 – volume: 275 start-page: 35986 year: 2000 ident: 10.1016/j.taap.2018.09.006_bb0305 article-title: Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta publication-title: J. Biol. Chem. doi: 10.1074/jbc.M006777200 – volume: 158 start-page: 131 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0370 article-title: From BPA to its analogues: is it a safe journey? publication-title: Chemosphere doi: 10.1016/j.chemosphere.2016.05.070 – volume: 40 start-page: 60 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0355 article-title: Mutagenic effect of Bisphenol A on adult rat male germ cells and their fertility publication-title: Reprod. Toxicol. doi: 10.1016/j.reprotox.2013.05.013 – volume: 46 start-page: 6860 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0205 article-title: Bisphenol S in urine from the United States and seven Asian countries: occurrence and human exposures publication-title: Environ Sci Technol doi: 10.1021/es301334j – volume: 12 start-page: 1973 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0090 article-title: DNA methylation in spermatogenesis and male infertility publication-title: Exp Ther Med doi: 10.3892/etm.2016.3569 – start-page: 579 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0170 – volume: 2 start-page: R15 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0225 article-title: Human infertility: are endocrine disruptors to blame? publication-title: Endocr Connect doi: 10.1530/EC-13-0036 – start-page: 153 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0310 article-title: Alteration in global DNA methylation after bisphenol a exposure in MCF-7 cells – volume: 138 start-page: 21 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0160 article-title: Coexposure to phytoestrogens and bisphenol a mimics estrogenic effects in an additive manner publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kft271 – volume: 30 start-page: 532 year: 2010 ident: 10.1016/j.taap.2018.09.006_bb0230 article-title: Semen quality and sperm DNA damage in relation to urinary bisphenol a among men from an infertility clinic publication-title: Reprod. Toxicol. doi: 10.1016/j.reprotox.2010.07.005 – volume: 106 start-page: 857 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0030 article-title: Bisphenol a and ovarian steroidogenesis publication-title: Fertil. Steril. doi: 10.1016/j.fertnstert.2016.08.021 – volume: 1 start-page: 231 year: 2011 ident: 10.1016/j.taap.2018.09.006_bb0415 article-title: Endocrine disrupting chemicals: multiple effects on testicular signaling and spermatogenesis publication-title: Spermatogenesis doi: 10.4161/spmg.1.3.18019 – volume: 118 start-page: 1055 year: 2010 ident: 10.1016/j.taap.2018.09.006_bb0380 article-title: Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A publication-title: Environ. Health Perspect. doi: 10.1289/ehp.0901716 – volume: 355 start-page: 49 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0075 article-title: 17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line publication-title: Mol. Cell. Endocrinol. doi: 10.1016/j.mce.2012.01.017 – volume: 428 start-page: 89 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb5005 article-title: Differential roles of estrogen receptors, ESR1 and ESR2, in adult rat spermatogenesis publication-title: Mol. Cell Endocrinol. doi: 10.1016/j.mce.2016.03.024 – volume: 34 start-page: 146 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0340 article-title: In vitro impact of bisphenols BPA, BPF, BPAF and 17beta-estradiol (E2) on human monocyte-derived dendritic cell generation, maturation and function publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2016.02.030 – volume: 49 start-page: 11834 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0410 article-title: Urinary concentrations of bisphenol A and three other bisphenols in convenience samples of U.S. adults during 2000-2014 publication-title: Environ Sci Technol doi: 10.1021/acs.est.5b02135 – volume: 13 start-page: 51 year: 2011 ident: 10.1016/j.taap.2018.09.006_bb0110 article-title: Distribution of causes of infertility in patients attending primary fertility clinics in Israel publication-title: Isr. Med. Assoc. J. – volume: 119 start-page: 1775 year: 2011 ident: 10.1016/j.taap.2018.09.006_bb0315 article-title: Low concentrations of bisphenol A induce mouse spermatogonial cell proliferation by G protein-coupled receptor 30 and estrogen receptor-α publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1103781 – volume: 615 start-page: 87 year: 2018 ident: 10.1016/j.taap.2018.09.006_bb0395 article-title: Occurrence of bisphenol S in the environment and implications for human exposure: a short review publication-title: Sci. Total Environ. doi: 10.1016/j.scitotenv.2017.09.194 – volume: 85 start-page: 352 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0020 article-title: Biomonitoring of human exposures to chlorinated derivatives and structural analogs of bisphenol A publication-title: Environ. Int. doi: 10.1016/j.envint.2015.09.011 – volume: 17 start-page: 2839 year: 2002 ident: 10.1016/j.taap.2018.09.006_bb0155 article-title: Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure publication-title: Hum. Reprod. doi: 10.1093/humrep/17.11.2839 – volume: 103 start-page: 11 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0105 article-title: A new chapter in the bisphenol A story: bisphenol S and bisphenol F are not safe alternatives to this compound publication-title: Fertil. Steril. doi: 10.1016/j.fertnstert.2014.11.005 – volume: 29 start-page: 883 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0190 article-title: Treatment with bisphenol A and methoxychlor results in the growth of human breast cancer cells and alteration of the expression of cell cycle-related genes, cyclin D1 and p21, via an estrogen receptor-dependent signaling pathway publication-title: Int. J. Mol. Med. – volume: 62 start-page: 684 year: 2010 ident: 10.1016/j.taap.2018.09.006_bb0035 article-title: Bisphenol a impairs estradiol-induced protective effects against DLD-1 colon cancer cell growth publication-title: IUBMB Life doi: 10.1002/iub.370 – volume: 13 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0010 article-title: Molecular mechanisms of action of BPA publication-title: Dose Response doi: 10.1177/1559325815610582 – volume: 2015 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0175 article-title: Serum bisphenol A level in boys with cryptorchidism: a step to male infertility? publication-title: Int. J. Endocrinol. doi: 10.1155/2015/973154 – volume: 13 start-page: 10143 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0330 article-title: Epigenetic effects of environmental chemicals bisphenol A and phthalates publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms130810143 – volume: 12 start-page: 303 year: 2006 ident: 10.1016/j.taap.2018.09.006_bb0285 article-title: Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects publication-title: Hum. Reprod. Update doi: 10.1093/humupd/dmk006 – volume: 116 start-page: 39 year: 2008 ident: 10.1016/j.taap.2018.09.006_bb0045 article-title: Exposure of the U.S. population to bisphenol a and 4-tertiary-octylphenol: 2003-2004 publication-title: Environ. Health Perspect. doi: 10.1289/ehp.10753 – volume: 130 start-page: 241 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0055 article-title: Bisphenol A promotes testicular seminoma cell proliferation through GPER/GPR30 publication-title: Int. J. Cancer doi: 10.1002/ijc.25972 – volume: 389 start-page: 71 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0255 article-title: Estrogen biology: new insights into GPER function and clinical opportunities publication-title: Mol. Cell. Endocrinol. doi: 10.1016/j.mce.2014.02.002 – volume: 7 start-page: 10606 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0400 article-title: Neonatal bisphenol a exposure induces meiotic arrest and apoptosis of spermatogenic cells publication-title: Oncotarget doi: 10.18632/oncotarget.7218 – volume: 160 start-page: 171 year: 2006 ident: 10.1016/j.taap.2018.09.006_bb0120 article-title: In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2005.07.001 – volume: 12 start-page: 26 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0385 article-title: Mixtures of xenoestrogens disrupt estradiol-induced non-genomic signaling and downstream functions in pituitary cells publication-title: Environ. Health doi: 10.1186/1476-069X-12-26 – volume: 272 start-page: 127 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0240 article-title: In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-a congeners and derivatives via nuclear receptors publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2013.05.015 – volume: 68 start-page: 1037 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0435 article-title: Bisphenol A stimulates human lung cancer cell migration via upregulation of matrix metalloproteinases by GPER/EGFR/ERK1/2 signal pathway publication-title: Biomed Pharmacother doi: 10.1016/j.biopha.2014.09.003 – volume: 226 start-page: 81 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0140 article-title: Involvement of activating ERK1/2 through G protein coupled receptor 30 and estrogen receptor α/β in low doses of bisphenol A promoting growth of Sertoli TM4 cells publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2014.01.035 – volume: 46 start-page: 6515 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0210 article-title: Bisphenol s, a new bisphenol analogue, in paper products and currency bills and its association with bisphenol a residues publication-title: Environ Sci Technol doi: 10.1021/es300876n – start-page: 28 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0235 – volume: 156 start-page: 4672 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0005 article-title: Prenatal exposures of male rats to the environmental chemicals bisphenol a and Di(2-Ethylhexyl) phthalate impact the sexual differentiation process publication-title: Endocrinology doi: 10.1210/en.2015-1077 – volume: 8 start-page: R19 year: 2007 ident: 10.1016/j.taap.2018.09.006_bb0150 article-title: qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data publication-title: Genome Biol. doi: 10.1186/gb-2007-8-2-r19 – volume: 139 start-page: 35 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0300 article-title: Are structural analogues to bisphenol a safe alternatives? publication-title: Toxicol. Sci. doi: 10.1093/toxsci/kfu030 – volume: 33 start-page: 601 year: 2017 ident: 10.1016/j.taap.2018.09.006_bb0320 article-title: Endocrine-disrupting chemicals-Mechanisms of action on male reproductive system publication-title: Toxicol. Ind. Health doi: 10.1177/0748233717695160 – volume: 25 start-page: 847 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0430 article-title: Exposure to bisphenol A results in a decline in mouse spermatogenesis publication-title: Reprod. Fertil. Dev. doi: 10.1071/RD12159 – volume: 103 start-page: 105 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0095 article-title: Expression of steroidogenesis-related genes in murine male germ cells publication-title: Steroids doi: 10.1016/j.steroids.2015.08.011 – volume: 94 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0135 article-title: Bisphenol A and hormone-associated cancers: current progress and perspectives publication-title: Medicine (Baltimore) doi: 10.1097/MD.0000000000000211 – volume: 25 start-page: 748 year: 2018 ident: 10.1016/j.taap.2018.09.006_bb0065 article-title: Bisphenol A in reproduction: epigenetic effects publication-title: Curr. Med. Chem. doi: 10.2174/0929867324666171009121001 – volume: 34 start-page: 703 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0100 article-title: Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells publication-title: Carcinogenesis doi: 10.1093/carcin/bgs379 – volume: 228 start-page: 57 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0220 article-title: Adverse effects of bisphenol A on male reproductive function publication-title: Rev. Environ. Contam. Toxicol. – volume: 308 start-page: 32 year: 2009 ident: 10.1016/j.taap.2018.09.006_bb0260 article-title: Mechanisms of estrogen signaling and gene expression via GPR30 publication-title: Mol. Cell. Endocrinol. doi: 10.1016/j.mce.2009.03.026 – volume: 39 start-page: 405 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0080 article-title: Increase in the expression of inducible nitric oxide synthase on exposure to bisphenol a: a possible cause for decline in steroidogenesis in male mice publication-title: Environ. Toxicol. Pharmacol. doi: 10.1016/j.etap.2014.09.014 – volume: 727 start-page: 62 year: 2011 ident: 10.1016/j.taap.2018.09.006_bb0280 article-title: Epigenetics, spermatogenesis and male infertility publication-title: Mutat. Res. doi: 10.1016/j.mrrev.2011.04.002 – volume: 16 start-page: 231 year: 2010 ident: 10.1016/j.taap.2018.09.006_bb0085 article-title: World Health Organization reference values for human semen characteristics publication-title: Hum. Reprod. Update doi: 10.1093/humupd/dmp048 – volume: 314 start-page: 98 year: 2017 ident: 10.1016/j.taap.2018.09.006_bb0425 article-title: The regulation of cellular apoptosis by the ROS-triggered PERK/EIF2α/chop pathway plays a vital role in bisphenol A-induced male reproductive toxicity publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2016.11.013 – volume: 6 start-page: 1472 issue: 4 year: 2009 ident: 10.1016/j.taap.2018.09.006_bb5000 article-title: Biodegradation of bisphenol A, bisphenol F and bisphenol S in seawater publication-title: Int. J. Environ. Res. Public Health doi: 10.3390/ijerph6041472 – volume: 67 start-page: 1859 year: 2007 ident: 10.1016/j.taap.2018.09.006_bb0015 article-title: G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells publication-title: Cancer Res. doi: 10.1158/0008-5472.CAN-06-2909 – volume: 641 start-page: 1 year: 2008 ident: 10.1016/j.taap.2018.09.006_bb0025 article-title: Impact of estrogenic compounds on DNA integrity in human spermatozoa: evidence for cross-linking and redox cycling activities publication-title: Mutat. Res. doi: 10.1016/j.mrfmmm.2008.02.002 – volume: 194 start-page: 1 year: 2018 ident: 10.1016/j.taap.2018.09.006_bb0265 article-title: Immunotoxicity of bisphenol S and F are similar to that of bisphenol A during zebrafish early development publication-title: Chemosphere doi: 10.1016/j.chemosphere.2017.11.125 – volume: 101 start-page: 315 year: 2012 ident: 10.1016/j.taap.2018.09.006_bb0050 article-title: Male reprotoxicity and endocrine disruption publication-title: EXS – volume: 306 start-page: 33 year: 2009 ident: 10.1016/j.taap.2018.09.006_bb0365 article-title: Epigenetics in spermatogenesis publication-title: Mol. Cell. Endocrinol. doi: 10.1016/j.mce.2008.12.018 – volume: 123 start-page: 643 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0295 article-title: Bisphenol S and F: a Systematic Review and Comparison of the Hormonal activity of Bisphenol A Substitutes publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1408989 – volume: 162 start-page: 35 year: 2018 ident: 10.1016/j.taap.2018.09.006_bb0405 article-title: Resin-based dental sealants as a source of human exposure to bisphenol analogues, bisphenol A diglycidyl ether, and its derivatives publication-title: Environ. Res. doi: 10.1016/j.envres.2017.12.011 – volume: 149 start-page: 5043 year: 2008 ident: 10.1016/j.taap.2018.09.006_bb0335 article-title: The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line publication-title: Endocrinology doi: 10.1210/en.2007-1593 – volume: 18 start-page: 413 year: 2002 ident: 10.1016/j.taap.2018.09.006_bb0360 article-title: Changes in male reproductive health and effects of endocrine disruptors in Scandinavian countries publication-title: Cad Saude Publica doi: 10.1590/S0102-311X2002000200005 – volume: 48 start-page: 265 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0420 article-title: Role of DNA methylation in bisphenol A exposed mouse spermatocyte publication-title: Environ. Toxicol. Pharmacol. doi: 10.1016/j.etap.2016.11.003 – volume: 167 start-page: 95 year: 2006 ident: 10.1016/j.taap.2018.09.006_bb0345 article-title: Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2006.08.012 – volume: 28 start-page: 373 year: 2014 ident: 10.1016/j.taap.2018.09.006_bb0270 article-title: Estrogen receptors are involved in polychlorinated biphenyl-induced apoptosis on mouse spermatocyte GC-2 cell line publication-title: Toxicol. in Vitro doi: 10.1016/j.tiv.2013.10.024 – volume: 23 start-page: 4070 year: 2016 ident: 10.1016/j.taap.2018.09.006_bb0060 article-title: Kisspeptins, Estrogens and Male Fertility publication-title: Curr. Med. Chem. doi: 10.2174/0929867323666160902155434 – volume: 124 start-page: 437 issue: 4 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0350 article-title: Bisphenol A, bisphenol S, and 4-hydroxyphenyl 4-isoprooxyphenylsulfone (BPSIP) in urine and blood of cashiers publication-title: Environ. Health Perspect. doi: 10.1289/ehp.1409427 – volume: 10 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0195 article-title: The molecular mechanism of bisphenol A (BPA) as an endocrine disruptor by interacting with nuclear receptors: insights from molecular dynamics (MD) simulations publication-title: PLoS One – volume: 4 start-page: e676 year: 2013 ident: 10.1016/j.taap.2018.09.006_bb0215 article-title: Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity publication-title: Cell Death Dis. doi: 10.1038/cddis.2013.203 – volume: 286 start-page: 589 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0125 article-title: Why endocrine disrupting chemicals (EDCs) challenge traditional risk assessment and how to respond publication-title: J. Hazard. Mater. doi: 10.1016/j.jhazmat.2014.12.012 – volume: 100 start-page: 1267 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0145 article-title: Male reproductive disorders, diseases, and costs of exposure to endocrine-disrupting chemicals in the European Union publication-title: J. Clin. Endocrinol. Metab. doi: 10.1210/jc.2014-4325 – volume: 18 start-page: 418 year: 2011 ident: 10.1016/j.taap.2018.09.006_bb0325 article-title: Human male infertility: a complex multifactorial phenotype publication-title: Reprod. Sci. doi: 10.1177/1933719111398148 – volume: 185 start-page: 237 year: 2017 ident: 10.1016/j.taap.2018.09.006_bb0185 article-title: Bisphenol A disrupts steroidogenesis and induces a sex hormone imbalance through c-Jun phosphorylation in Leydig cells publication-title: Chemosphere doi: 10.1016/j.chemosphere.2017.07.004 – volume: 5 year: 2017 ident: 10.1016/j.taap.2018.09.006_bb0290 article-title: EDCs Mixtures: a Stealthy Hazard for Human Health? publication-title: Toxics doi: 10.3390/toxics5010005 – volume: 113 start-page: 391 year: 2005 ident: 10.1016/j.taap.2018.09.006_bb0040 article-title: Urinary concentrations of bisphenol a and 4-nonylphenol in a human reference population publication-title: Environ. Health Perspect. doi: 10.1289/ehp.7534 – volume: 116 start-page: 32 year: 2008 ident: 10.1016/j.taap.2018.09.006_bb0245 article-title: Direct evidence revealing structural elements essential for the high binding ability of bisphenol a to human estrogen-related receptor-gamma publication-title: Environ. Health Perspect. doi: 10.1289/ehp.10587 – volume: 5 start-page: 9169 year: 2015 ident: 10.1016/j.taap.2018.09.006_bb0275 article-title: Bisphenol-A affects male fertility via fertility-related proteins in spermatozoa publication-title: Sci. Rep. doi: 10.1038/srep09169 |
| SSID | ssj0009441 |
| Score | 2.4203687 |
| Snippet | Environmental factors, particularly xenoestrogens adversely affect reproductive health and their main mechanism is based on steroid-signaling pathway... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1 |
| Title | Cellular, transcriptomic and methylome effects of individual and combined exposure to BPA, BPF, BPS on mouse spermatocyte GC-2 cell line |
| URI | https://dx.doi.org/10.1016/j.taap.2018.09.006 https://www.ncbi.nlm.nih.gov/pubmed/30196065 https://www.proquest.com/docview/2101917306 |
| Volume | 359 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Na9tAEF1CcimUkqRfadMwgZJLraaSdlfW0TV1nJQGQxPwbdnsjsDBlUyiQH3JOT87M1rJptDm0ItAZoXFznjmzXreGyE-UsxPXOZ0lFuZRJK8IrIypVvtlPbOub5movCPcz2-lGdTNd0Qw44Lw22VbewPMb2J1u0nx-1uHi9mM-b4SlammZJTkifqKTPYZcZe_vl-3eaRSxmm5kkqm2l1S5wJPV61taxZGfcbrVOeevT35PQv8NkkodG2eNGiRxiEF9wRG1juiqNJkJ9e9uBizaa67cERTNbC1Mtd8Tyc0UGgHr0UD0Ocz7kNtQc1p6wmgDBLGWzpgWdLUzX_C6Ht-YCqgNmKv9WsoV2jyho94O9FxWeNUFfwdTLo0WXEl59QlcCnCwgsSU7wuHLLGuFkGCXAfxoAw9xX4nL07WI4jtrJDJFLla6jPqEWptyilzp2LisKLQtMUedXqGJLEZas7Ck_YkL4q68UqowDaWqTQhGmSV-LzbIq8a0Abz3aVOdWOSe9zHKuUOOmVpO-QL0n4s4kxrWy5Tw9Y266_rRrw2Y0bEbzJTdkxj3xafXMIoh2PLladZY2f7ieoazy5HOHnVsY-k3yntkSaUcNldFcBqe85k3wl9V7pCxIRLjv3X9-63vxjO-YDhmrfbFZ39zhB8JF9dVB4_gHYmtw-n18_ggQegw0 |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9tAEF7S5NBCKEn6SJo2nULJpVZTSbtr65iYuG6bBEMd8G3Z7I7AxZVMq0J8yTk_uzNayabQ5JCLQNIKiZ3Zeazm-0aI92TzE9d1OsqsTCJJWhFZmdKpdkp751xPM1D4_EIPL-XXiZqsiX6LheGyysb2B5teW-vmylEzm0fz6ZQxvpKZaSaklKSJevJIbEhavtzG4OPNqs4jkzK0zZOUN9PwBjkTirwqa5m0Mu7VZKfc9uj_3umu6LP2QoMt8bQJH-E4fOG2WMNiRxyOAv_0ogPjFZzqdwcOYbRipl7siM2wSQcBe_RM3PZxNuM61A5U7LNqC8IwZbCFB24uTen8T4Sm6APKHKZLAFc9hqaNUmv0gNfzkjcboSrhZHTcocOAD9-hLIC3FxCYk5zi49ItKoTP_SgB_msAHOc-F5eD03F_GDWtGSKXKl1FPQpbGHOLXurYuW6ea5ljijq7QhVbMrEkZk8OEhMKwHpKoeqyJU1tkisKatIXYr0oC9wV4K1Hm-rMKuekl92MU9S4Ttakz1HvibgViXENbzm3z5iZtkDth2ExGhaj-ZQZEuOe-LB8Zh5YO-4drVpJm390z5Bbufe5d61aGFqUPGe2QJpRQ3k058Epj3kZ9GX5HSkzElHg9-qBb30rHg_H52fm7MvFt33xhO8wNjJWr8V69esPvqEgqbo6qBfBXxLMDcI |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Cellular%2C+transcriptomic+and+methylome+effects+of+individual+and+combined+exposure+to+BPA%2C+BPF%2C+BPS+on+mouse+spermatocyte+GC-2+cell+line&rft.jtitle=Toxicology+and+applied+pharmacology&rft.au=Sidorkiewicz%2C+Iwona&rft.au=Czerniecki%2C+Jan&rft.au=Jarz%C4%85bek%2C+Katarzyna&rft.au=Zbucka-Kr%C4%99towska%2C+Monika&rft.date=2018-11-15&rft.issn=0041-008X&rft.volume=359&rft.spage=1&rft.epage=11&rft_id=info:doi/10.1016%2Fj.taap.2018.09.006&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_taap_2018_09_006 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0041-008X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0041-008X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0041-008X&client=summon |