Validated HILIC–MS/MS assay for determination of vindesine in human plasma: Application to a population pharmacokinetic study

Mean plasma concentration–time profiles of intravenous injection of 3mg Vindesine Sulfate for Injection to 100 unrelated Chinese Han subjects with hematological malignant disorders. •HILIC separation mode coupled to ESI-MS/MS was used for quantitative analysis.•The analytes of interest were well sep...

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Bibliographic Details
Published inJournal of pharmaceutical and biomedical analysis Vol. 96; pp. 31 - 36
Main Authors Zhu, Rong-Hua, Li, Huan-De, Cai, Hua-Lin, Jiang, Zhi-Ping, Xu, Ping, Dai, Li-Bo, Peng, Wen-Xing
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 05.08.2014
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