Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes—a meta-analysis

• Published in: Osteoporosis international Vol. 18; no. 4; pp. 427 - 444
• Main Author: Vestergaard, P.
• Format: Journal Article
• Language: English
• Published: London Springer 01.04.2007; Springer Nature B.V
• Subjects: Adult; Aged; Biological and medical sciences; Body Mass Index; Bone density; Bone Density - physiology; Diabetes; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - physiopathology; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - physiopathology; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Fractures; Fractures, Bone - etiology; Fractures, Bone - physiopathology; Glycated Hemoglobin A - analysis; Hip Fractures - etiology; Hip Fractures - physiopathology; Hip joint; Humans; Injuries of the limb. Injuries of the spine; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Meta-analysis; Middle Aged; Osteoarticular system. Muscles; Osteoporosis; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Risk; Risk Factors; Spine; Traumas. Diseases due to physical agents; Endocrinopathy; Type 2 diabetes; Human; Immunopathology; Diseases of the osteoarticular system; Autoimmune disease; Metabolic diseases; Fracture; Trauma; Meta-analysis; Osteoporosis; Type 1 diabetes; Risk factor; Bone mineral density; Diabetes

Diabetes affects bone metabolism. The hypothesis was that type 1 (T1D) and type 2 (T2D) affects BMD and fracture risk differently. Pubmed, Embase, and Web of Science were searched using the terms "diabetes", "fracture", and "bone mineral". Hip fracture risk was increase...