Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer

• Published in: Molecular cancer research Vol. 20; no. 4; pp. 527 - 541
• Main Authors: Van den Broeck, Thomas, Moris, Lisa, Gevaert, Thomas, Davicioni, Elai, Boeckx, Bram, Lambrechts, Diether, Helsen, Christine, Handle, Florian, Ghesquière, Bart, Soenen, Stefaan, Smeets, Elien, Eerlings, Roy, El Kharraz, Sarah, Devlies, Wout, Karnes, R Jeffrey, Lotan, Tamara, Van Poppel, Hendrik, Joniau, Steven, Claessens, Frank
• Format: Journal Article
• Language: English
• Published: United States 01.04.2022
• Subjects: Case-Control Studies; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Prostate; Prostatic Neoplasms - genetics; Retrospective Studies; Transcriptome

Molecular drivers of metastasis in patients with high-risk localized prostate cancer are poorly understood. Therefore, we aim to study molecular drivers of metastatic progression in patients with high-risk prostate cancer. A retrospective matched case-control study of two clinico-pathologically iden...