LC-MS-based serum metabolomics analysis and potential biomarkers for oxaliplatin induced neurotoxicity in colorectal cancer - Hua, Yujiao; Lv, Juan; Zhang, Yan; Ding, Yongjuan; Chen, Jinghua (Journal of pharmaceutical and biomedical analysis, 2025)
Keywords: Adult; Aged; Antineoplastic Agents - adverse effects; Biomarkers - blood; Chromatography, Liquid - methods; Colorectal cancer; Colorectal Neoplasms - blood; Colorectal Neoplasms - drug therapy; Female; Humans; Liquid Chromatography-Mass Spectrometry; Male; Mass Spectrometry - methods; Metabolomics - methods; Middle Aged; Neurotoxicity Syndromes - blood; Neurotoxicity Syndromes - diagnosis; Neurotoxicity Syndromes - etiology; Nontargeted metabolomics; OIPN; Oxaliplatin; Oxaliplatin - adverse effects; Peripheral Nervous System Diseases - blood; Peripheral Nervous System Diseases - chemically induced; Peripheral Nervous System Diseases - diagnosis; Oxaliplatin; OIPN; Nontargeted metabolomics; Colorectal cancer