Dipeptidyl carboxypeptidase from human seminal plasma

• Published in: Biochimica et biophysica acta Vol. 523; no. 2; pp. 469 - 476
• Main Authors: Depierre, D, Bargetzi, J P, Roth, M
• Format: Journal Article
• Language: English
• Published: Netherlands 12.04.1978
• Subjects: Dipeptides; Humans; Kinetics; Male; Molecular Weight; Peptidyl-Dipeptidase A - metabolism; Semen - enzymology; Substrate Specificity

Dipeptidyl carboxypeptidase (angiotensin I converting enzyme) was purified from human seminal plasma. The apparent relative molecular mass determined by gel filtration on Sephadex G-200 was 330 000. The pI in isoelectric focusing was 4.6--5.0 and the optimum pH 7.7--8.0. The enzyme is activated by c...