A stepwise reduction in plasma and salivary nitrite with increasing strengths of mouthwash following a dietary nitrate load

• Published in: Nitric oxide Vol. 54; pp. 1 - 7
• Main Authors: Woessner, Mary, Smoliga, James M., Tarzia, Brendan, Stabler, Thomas, Van Bruggen, Mitch, Allen, Jason D.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2016
• Subjects: Adult; Anti-Infective Agents, Local; Beta vulgaris; Blood Pressure; Cetylpyridinium; Chlorhexidine; Diet; Drug Combinations; Fruit and Vegetable Juices; Humans; Male; Middle Aged; Mouthwash; Mouthwashes - adverse effects; Nitrate; Nitrates - administration & dosage; Nitric oxide; Nitric Oxide - blood; Nitrite; Nitrites - blood; Oral bacteria; Salicylates; Saliva - chemistry; Terpenes; Water; Mouthwash; Blood pressure; Oral bacteria; Nitrate; Nitrite; Nitric oxide

Nitric Oxide (NO) bioavailability is essential for vascular health. Dietary supplementation with inorganic nitrate, which is abundant in vegetables and roots, has been identified as an effective means of increasing vascular NO bioavailability. Recent studies have shown a reduction in resting blood p...