Portable fiber-optic SPR platform for the detection of NS1-antigen for dengue diagnosis

• Published in: Biosensors & bioelectronics Vol. 196; p. 113720
• Main Authors: Gahlaut, Shashank K., Pathak, Anisha, Gupta, Banshi D., Singh, J.P.
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.01.2022
• Subjects: Biosensing Techniques; Dengue; Dengue - diagnosis; Fiber Optic Technology; Humans; NS1 antigen; Optical fiber; Selectivity; Sensor; Silver; Surface Plasmon Resonance; Surface plasmons; NS1 antigen; Selectivity; Surface plasmons; Dengue; Sensor; Optical fiber

Here, we present a portable, selective and cost-effective fiber-optic surface plasmon resonance (SPR) based platform for early detection of Dengue virus. NS1 protein was targeted as the biomarker of dengue. Antibody-antigen specific binding was exploited for NS1 antigen detection. The binding of ant...