Routine closed-suction drainage reduces seromas following totally extraperitoneal (TEP) inguinal hernia repair: A meta-analysis

The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes. A s...

Full description

Saved in:
Bibliographic Details
Published inMedicine (Baltimore) Vol. 103; no. 11; p. e37412
Main Authors Prassas, Dimitrios, Zaczek, Michael, David, Stephan Oliver, Knoefel, Wolfram Trudo, Vaghiri, Sascha
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins 15.03.2024
Subjects
Online AccessGet full text

Cover

Loading…
Abstract The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes. A systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals were calculated. Four studies were identified, involving a total of 1626 cases (Drain: n = 1251, no Drain: n = 375). There was a statistically significant difference noted between the 2 groups regarding postoperative seroma formation favoring the Drain group (odds ratio = 0.12; 95% confidence intervals [0.05, 0.29]; P < .001; 4 studies; I2 = 72%). For the remaining secondary endpoints postoperative urinary retention, recurrence, mesh infection and in-hospital length of stay no statistically significant difference was noted between the 2 study groups. Current evidence suggests that patients who underwent TEP with routine closed-suction drain placement developed significantly fewer seromas without any additional morbidity or prolongation of in-hospital stay.
AbstractList The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes. A systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals were calculated. Four studies were identified, involving a total of 1626 cases (Drain: n = 1251, no Drain: n = 375). There was a statistically significant difference noted between the 2 groups regarding postoperative seroma formation favoring the Drain group (odds ratio = 0.12; 95% confidence intervals [0.05, 0.29]; P < .001; 4 studies; I2 = 72%). For the remaining secondary endpoints postoperative urinary retention, recurrence, mesh infection and in-hospital length of stay no statistically significant difference was noted between the 2 study groups. Current evidence suggests that patients who underwent TEP with routine closed-suction drain placement developed significantly fewer seromas without any additional morbidity or prolongation of in-hospital stay.
Background: The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes. Methods: A systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals were calculated. Results: Four studies were identified, involving a total of 1626 cases (Drain: n = 1251, no Drain: n = 375). There was a statistically significant difference noted between the 2 groups regarding postoperative seroma formation favoring the Drain group (odds ratio = 0.12; 95% confidence intervals [0.05, 0.29]; P < .001; 4 studies; I 2 = 72%). For the remaining secondary endpoints postoperative urinary retention, recurrence, mesh infection and in-hospital length of stay no statistically significant difference was noted between the 2 study groups. Conclusion: Current evidence suggests that patients who underwent TEP with routine closed-suction drain placement developed significantly fewer seromas without any additional morbidity or prolongation of in-hospital stay.
The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes.BACKGROUNDThe value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a meta-analysis of studies examining postoperative seroma rates in patients with or without routine placement of closed-suction drainage tubes.A systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals were calculated.METHODSA systematic literature search was conducted for trials comparing the outcome of TEP with or without routine drainage placement. Data regarding postoperative outcomes were extracted and compared by meta-analysis. The odds ratio and standardized mean differences with 95% confidence intervals were calculated.Four studies were identified, involving a total of 1626 cases (Drain: n = 1251, no Drain: n = 375). There was a statistically significant difference noted between the 2 groups regarding postoperative seroma formation favoring the Drain group (odds ratio = 0.12; 95% confidence intervals [0.05, 0.29]; P < .001; 4 studies; I2 = 72%). For the remaining secondary endpoints postoperative urinary retention, recurrence, mesh infection and in-hospital length of stay no statistically significant difference was noted between the 2 study groups.RESULTSFour studies were identified, involving a total of 1626 cases (Drain: n = 1251, no Drain: n = 375). There was a statistically significant difference noted between the 2 groups regarding postoperative seroma formation favoring the Drain group (odds ratio = 0.12; 95% confidence intervals [0.05, 0.29]; P < .001; 4 studies; I2 = 72%). For the remaining secondary endpoints postoperative urinary retention, recurrence, mesh infection and in-hospital length of stay no statistically significant difference was noted between the 2 study groups.Current evidence suggests that patients who underwent TEP with routine closed-suction drain placement developed significantly fewer seromas without any additional morbidity or prolongation of in-hospital stay.CONCLUSIONCurrent evidence suggests that patients who underwent TEP with routine closed-suction drain placement developed significantly fewer seromas without any additional morbidity or prolongation of in-hospital stay.
Author Vaghiri, Sascha
Zaczek, Michael
David, Stephan Oliver
Prassas, Dimitrios
Knoefel, Wolfram Trudo
Author_xml – sequence: 1
  givenname: Dimitrios
  orcidid: 0000-0001-8039-6284
  surname: Prassas
  fullname: Prassas, Dimitrios
  organization: Heinrich-Heine-University and University Hospital Duesseldorf, Department of Surgery (A), Duesseldorf, Germany
– sequence: 2
  givenname: Michael
  surname: Zaczek
  fullname: Zaczek, Michael
  organization: Katholisches Klinikum Essen, Department of Surgery, Essen Germany
– sequence: 3
  givenname: Stephan Oliver
  surname: David
  fullname: David, Stephan Oliver
  organization: Heinrich-Heine-University and University Hospital Duesseldorf, Department of Surgery (A), Duesseldorf, Germany
– sequence: 4
  givenname: Wolfram Trudo
  surname: Knoefel
  fullname: Knoefel, Wolfram Trudo
  organization: Heinrich-Heine-University and University Hospital Duesseldorf, Department of Surgery (A), Duesseldorf, Germany
– sequence: 5
  givenname: Sascha
  surname: Vaghiri
  fullname: Vaghiri, Sascha
  organization: Heinrich-Heine-University and University Hospital Duesseldorf, Department of Surgery (A), Duesseldorf, Germany
BackLink https://www.ncbi.nlm.nih.gov/pubmed/38489721$$D View this record in MEDLINE/PubMed
BookMark eNpdkU1vFDEMhiNURLeFX4CEcmwPUzLJJDPhgqq2fEitQKicI0_Wsw3KJEuSAfbEXydVS_nwxZL9-vEr-4DshRiQkOctO2mZ7l9enZ-wPyH6ruWPyKqVQjVSq26PrBjjsul13-2Tg5y_MNaKnndPyL4YukH3vF2Rn5_iUlxAan3MuG7yYouLga4TuAAbpAnXi8VMM6Y4Q6ZT9D5-d2FDSyzg_Y7ij5Jgi8mV6g88Pbq--HhMq2KpBE9vMAUHlbMFl17RUzpjgQZqa5ddfkoeT-AzPrvPh-Tzm4vrs3fN5Ye3789OLxsrpCqN5GyUMNhugkGMcgTNLfBa4EzWJHFifcfGwY5atZIxpQalbddpZa1WUopD8vqOu13GGdcWQzXtzTa5GdLORHDm305wN2YTv5l6aqGlHCrh6J6Q4tcFczGzyxa9h4BxyYZrOXBd73orFXdSm2LOCaeHPS27Bfbm6tz8_7s69eJviw8zv58lfgEsm5k0
Cites_doi 10.1007/PL00002599
10.1007/s10029-018-1731-2
10.1007/s10029-014-1310-0
10.1371/journal.pmed.1003583
10.1097/SLE.0000000000001045
10.1097/SLE.0b013e3181a4d0e1
10.1186/s12893-022-01900-9
10.1136/bmj.l4898
10.1016/j.jclinepi.2011.03.017
10.1136/bmj.j4008
10.1007/s00268-010-0730-y
10.1007/s10029-009-0529-7
10.1007/s10029-020-02136-3
10.1001/archsurg.2011.2023
10.1007/s00464-011-1931-7
10.1136/bmj.i4919
10.1007/s10029-007-0233-4
10.1007/s10029-023-02785-0
ContentType Journal Article
Copyright Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. 2024
Copyright_xml – notice: Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
– notice: Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc. 2024
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
5PM
DOI 10.1097/MD.0000000000037412
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
MEDLINE - Academic
DatabaseTitleList MEDLINE
CrossRef
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1536-5964
ExternalDocumentID 10_1097_MD_0000000000037412
38489721
Genre Meta-Analysis
Systematic Review
Journal Article
GroupedDBID ---
.-D
.XZ
.Z2
01R
0R~
354
40H
4Q1
4Q2
4Q3
5GY
5RE
5VS
71W
77Y
7O~
8L-
AAAAV
AAGIX
AAHPQ
AAIQE
AAMOA
AAQKA
AARTV
AASCR
AAWTL
AAXQO
AAYEP
ABASU
ABBUW
ABCQX
ABDIG
ABFRF
ABOCM
ABVCZ
ABXVJ
ABZAD
ACDDN
ACEWG
ACGFO
ACGFS
ACILI
ACWDW
ACWRI
ACXJB
ACXNZ
ADGGA
ADHPY
ADNKB
ADPDF
AE6
AEFWE
AENEX
AFDTB
AGOPY
AHOMT
AHQNM
AHVBC
AIJEX
AINUH
AJIOK
AJNWD
AJNYG
AJZMW
AKULP
ALMA_UNASSIGNED_HOLDINGS
ALMTX
AMJPA
AMKUR
AMNEI
AOHHW
AWKKM
BQLVK
CGR
CS3
CUY
CVF
DIWNM
DU5
E.X
EBS
ECM
EEVPB
EIF
ERAAH
EX3
F2K
F2L
F2M
F2N
F5P
FCALG
FD6
FIJ
FL-
GNXGY
GQDEL
GROUPED_DOAJ
H0~
HLJTE
HYE
HZ~
H~9
IKREB
IKYAY
IN~
IPNFZ
JK3
JK8
K8S
KD2
KMI
KQ8
L-C
N9A
NPM
N~7
N~B
O9-
OAG
OAH
OB2
ODA
OHH
OK1
OL1
OLB
OLG
OLH
OLU
OLV
OLY
OLZ
OPUJH
OUVQU
OVD
OVDNE
OVEED
OVIDH
OVLEI
OWV
OWW
OWZ
OXXIT
P2P
RIG
RLZ
RPM
RXW
S4R
S4S
TAF
TEORI
TSPGW
UNMZH
V2I
VVN
W3M
WOQ
WOW
X3V
X3W
XYM
YFH
YOC
ZFV
ZY1
AAYXX
CITATION
7X8
5PM
ID FETCH-LOGICAL-c356t-520b5a8c4fa83b5ba92ca2a8c2052a85ef0740b8cb96150066869c4496cc96553
IEDL.DBID RPM
ISSN 0025-7974
1536-5964
IngestDate Tue Sep 17 21:28:57 EDT 2024
Fri Aug 23 20:14:20 EDT 2024
Thu Aug 22 15:03:09 EDT 2024
Wed Oct 02 05:22:13 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 11
Language English
License Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c356t-520b5a8c4fa83b5ba92ca2a8c2052a85ef0740b8cb96150066869c4496cc96553
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Undefined-3
ORCID 0000-0001-8039-6284
OpenAccessLink https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939558/
PMID 38489721
PQID 2958294898
PQPubID 23479
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_10939558
proquest_miscellaneous_2958294898
crossref_primary_10_1097_MD_0000000000037412
pubmed_primary_38489721
PublicationCentury 2000
PublicationDate 2024-Mar-15
2024-03-15
20240315
PublicationDateYYYYMMDD 2024-03-15
PublicationDate_xml – month: 03
  year: 2024
  text: 2024-Mar-15
  day: 15
PublicationDecade 2020
PublicationPlace United States
PublicationPlace_xml – name: United States
– name: Hagerstown, MD
PublicationTitle Medicine (Baltimore)
PublicationTitleAlternate Medicine (Baltimore)
PublicationYear 2024
Publisher Lippincott Williams & Wilkins
Publisher_xml – name: Lippincott Williams & Wilkins
References Shea (R14-20240803) 2017; 21
Wu (R8-20240803) 2023; 23
Hitman (R19-20240803) 2023; 27
Dulucq (R2-20240803) 1992; 118
Page (R10-20240803) 2021; 18
Ismail (R6-20240803) 2009; 19
Fan (R7-20240803) 2018; 22
Gao (R9-20240803) 2015; 19
Sterne (R12-20240803) 2019; 366
Krishna (R5-20240803) 2012; 26
Reddy (R17-20240803) 2007; 11
Kurtulus (R18-20240803) 2022; 32
Liu (R4-20240803) 2020; 24
Eker (R15-20240803) 2012; 147
Simons (R3-20240803) 2009; 13
Guyatt (R13-20240803) 2011; 64
Sterne (R11-20240803) 2016; 355
Myers (R16-20240803) 2012; 34
Jähne (R1-20240803) 2001; 72
References_xml – volume: 72
  start-page: 456
  year: 2001
  ident: R1-20240803
  article-title: Surgery of inguinal hernia.
  publication-title: Chirurg
  doi: 10.1007/PL00002599
  contributor:
    fullname: Jähne
– volume: 22
  start-page: 455
  year: 2018
  ident: R7-20240803
  article-title: Preperitoneal closed-system suction drainage after totally extraperitoneal hernioplasty in the prevention of early seroma formation: a prospective double-blind randomised controlled trial.
  publication-title: Hernia
  doi: 10.1007/s10029-018-1731-2
  contributor:
    fullname: Fan
– volume: 19
  start-page: 789
  year: 2015
  ident: R9-20240803
  article-title: Clinical research of preperitoneal drainage after endoscopic totally extraperitoneal inguinal hernia repair.
  publication-title: Hernia
  doi: 10.1007/s10029-014-1310-0
  contributor:
    fullname: Gao
– volume: 18
  start-page: et1003583
  year: 2021
  ident: R10-20240803
  article-title: The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.
  publication-title: PLoS Med
  doi: 10.1371/journal.pmed.1003583
  contributor:
    fullname: Page
– volume: 32
  start-page: 329
  year: 2022
  ident: R18-20240803
  article-title: Zig Maneuver in total extraperitoneal inguinal hernia repair.
  publication-title: Surg Laparosc Endosc Percutan Tech
  doi: 10.1097/SLE.0000000000001045
  contributor:
    fullname: Kurtulus
– volume: 118
  start-page: 83
  year: 1992
  ident: R2-20240803
  article-title: Treatment of inguinal hernia by insertion of a subperitoneal patch under pre-peritoneoscopy.
  publication-title: Chirurgie
  contributor:
    fullname: Dulucq
– volume: 19
  start-page: 263
  year: 2009
  ident: R6-20240803
  article-title: Impact of closed-suction drain in preperitoneal space on the incidence of seroma formation after laparoscopic total extraperitoneal inguinal hernia repair.
  publication-title: Surg Laparosc Endosc Percutan Tech
  doi: 10.1097/SLE.0b013e3181a4d0e1
  contributor:
    fullname: Ismail
– volume: 23
  start-page: 14
  year: 2023
  ident: R8-20240803
  article-title: Laparoscopic total extraperitoneal (TEP) inguinal hernia repair with preperitoneal closed-suction drainage reduced postoperative complications.
  publication-title: BMC Surg
  doi: 10.1186/s12893-022-01900-9
  contributor:
    fullname: Wu
– volume: 366
  start-page: i4898
  year: 2019
  ident: R12-20240803
  article-title: RoB 2: a revised tool for assessing risk of bias in randomised trials.
  publication-title: BMJ
  doi: 10.1136/bmj.l4898
  contributor:
    fullname: Sterne
– volume: 64
  start-page: 1294
  year: 2011
  ident: R13-20240803
  article-title: GRADE guidelines: 7. Rating the quality of evidence--inconsistency.
  publication-title: J Clin Epidemiol
  doi: 10.1016/j.jclinepi.2011.03.017
  contributor:
    fullname: Guyatt
– volume: 21
  start-page: j4008
  year: 2017
  ident: R14-20240803
  article-title: AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both.
  publication-title: BMJ
  doi: 10.1136/bmj.j4008
  contributor:
    fullname: Shea
– volume: 34
  start-page: 3059
  year: 2012
  ident: R16-20240803
  article-title: Laparoscopic (TEP) versus lichtenstein inguinal hernia repair: a comparison of quality-of-life outcomes.
  publication-title: World J Surg
  doi: 10.1007/s00268-010-0730-y
  contributor:
    fullname: Myers
– volume: 13
  start-page: 343
  year: 2009
  ident: R3-20240803
  article-title: European hernia society guidelines on the treatment of inguinal hernia in adult patients.
  publication-title: Hernia
  doi: 10.1007/s10029-009-0529-7
  contributor:
    fullname: Simons
– volume: 24
  start-page: 821
  year: 2020
  ident: R4-20240803
  article-title: Does the use of monopolar energy as the preferred mode of dissection effectively reduce seroma formation in laparoscopic total extra peritoneal hernioplasty? A prospective double-blinded randomized control trial.
  publication-title: Hernia
  doi: 10.1007/s10029-020-02136-3
  contributor:
    fullname: Liu
– volume: 147
  start-page: 256
  year: 2012
  ident: R15-20240803
  article-title: Randomized clinical trial of total extraperitoneal inguinal hernioplasty vs lichtenstein repair: a long-term follow-up study.
  publication-title: Arch Surg
  doi: 10.1001/archsurg.2011.2023
  contributor:
    fullname: Eker
– volume: 26
  start-page: 639
  year: 2012
  ident: R5-20240803
  article-title: Laparoscopic inguinal hernia repair: transabdominal preperitoneal (TAPP) versus totally extraperitoneal (TEP) approach: a prospective randomized controlled trial.
  publication-title: Surg Endosc
  doi: 10.1007/s00464-011-1931-7
  contributor:
    fullname: Krishna
– volume: 355
  start-page: i4919
  year: 2016
  ident: R11-20240803
  article-title: ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.
  publication-title: BMJ
  doi: 10.1136/bmj.i4919
  contributor:
    fullname: Sterne
– volume: 11
  start-page: 393
  year: 2007
  ident: R17-20240803
  article-title: Laparoscopic repair of direct inguinal hernia: a new technique that reduces the development of postoperative seroma.
  publication-title: Hernia
  doi: 10.1007/s10029-007-0233-4
  contributor:
    fullname: Reddy
– volume: 27
  start-page: 1047
  year: 2023
  ident: R19-20240803
  article-title: Comparison of bilateral to unilateral total extra-peritoneal (TEP) inguinal hernia repair: a systematic review and meta-analysis.
  publication-title: Hernia
  doi: 10.1007/s10029-023-02785-0
  contributor:
    fullname: Hitman
SSID ssj0013724
Score 2.4616013
SecondaryResourceType review_article
Snippet The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We conducted a...
Background: The value of prophylactic closed-suction drainage in totally extraperitoneal inguinal hernia repair (TEP) is still a matter of controversy. We...
SourceID pubmedcentral
proquest
crossref
pubmed
SourceType Open Access Repository
Aggregation Database
Index Database
StartPage e37412
SubjectTerms Drainage - adverse effects
Drainage - methods
Hernia, Inguinal - surgery
Herniorrhaphy - adverse effects
Herniorrhaphy - methods
Humans
Length of Stay - statistics & numerical data
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Postoperative Complications - prevention & control
Seroma - epidemiology
Seroma - etiology
Seroma - prevention & control
Suction - methods
Systematic Review and Meta-Analysis
Title Routine closed-suction drainage reduces seromas following totally extraperitoneal (TEP) inguinal hernia repair: A meta-analysis
URI https://www.ncbi.nlm.nih.gov/pubmed/38489721
https://www.proquest.com/docview/2958294898/abstract/
https://pubmed.ncbi.nlm.nih.gov/PMC10939558
Volume 103
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3fa9swED7aFMpextatW7Y2qLCHDuom0Q9b6ltpEkIhbR_a0jcjKTIzJE5IHEqf9q_vZEeh6d7qFxtZloXu0H3Hnb4D-GU8jOBuHHGW6YhbkUQ6UTTSHcZFZhwi6Irt8yYePvDrJ_G0A3E4C1Ml7VuTnxeT6XmR_6lyK-dT2w55Yu270ZWnQFJCyPYu7CaMBR89xA4SyjeFWhEuB64hlbRHvZqvsL4YWlO6bY_-A5lvcyVfGZ_BJ_i4Ro3ksp7dZ9hxxQHsj9Zx8S_w1yf24BOxk9kSl2RZc8KSsS8AgTsGWXiGVrckqHA-IYhkKP7ZM5otUs4Qfk9eCG7S_iDWIvfs3Piv0_v-3W-CPVa-bhZB0Ra5xnHmOl9ckEsydaWO9JrS5Cs8DPr3V8NoXVohskzEJbqfHSO0tDzTkhlhtKJWU2ygHYE34TKEFh0jrVGeMR5xiYyV5VzF1qpYCHYIjQKn8x0I4sesO6Y26aqMjzWT0inTlbGNM-1sIppwFhY4ndcMGmmIfI966Vt5NOEkCCFFTffhC1242WqZUiUkVVwq2YRvtVA2AzKJ7ejMNkFuiWvTwbNob79B5arYtIMy_Xj_pz_hA0Ws41PTuuIIGuVi5Y4Rq5SmVfn4Ldi7fez3e61KUf8B-yHspw
link.rule.ids 230,315,733,786,790,870,891,27957,27958,53827,53829
linkProvider National Library of Medicine
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NT9swFH9iTGJc2Mb4KOzDkzgwaemHYyf2bogPdRtBHIrGLbJdR0S0adWmQuyyf53npK7W7sRySWQ7jpP3nPez3vPvARxpByOY7QcszFTADI8DFUsaqHbIeKYtIuiK7fMq6t6wH7f8dg0ivxemCto3Om8Wg2GzyO-q2Mrx0LR8nFjrOjl1FEiSc9F6AS9xwtLYr9K99yCmbJGqFQGzZxuScSs5qxkL6yNEe0qXLdI_MHM1WvIv83PxGn75gddRJ_fNWamb5vcKp-Pz3-wNbM0RKTmp69_Cmi22YSOZ-9zfwR8XNIRXxAxGU_zc05pvlvRdcgn8G5GJY3-1U4LK7IKNSIaqNXpAk0jKEUL7wSNBA-A2eU1yx_yNzzrunV9_Idhi5nJyEVSbIlfYz1jlk2_khAxtqQI1p0vZgZuL895pN5inbQhMyKMSl7ZtzZUwLFMi1FwrSY2iWEDbHE_cZghb2loYLR0bPWIeEUnDmIyMkRHn4S6sFzicfSCITbNOn5q4IzPWV6EQVuqOiEyUKWti3oCvXnTpuGbnSL1XPTlLVyXdgM9evCnOIucaUYUdzaYplVxQyYQUDdirxb3oMBRYjgvlBoglRVg0cAzdyzUo3oqp24vz4P9v_QSvur3kMr38fvXzEDYpYioXAtfh72G9nMzsB8REpf5YTYAnAAcMXA
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lj9MwEB7BIq24LG_o8jISB5BI0zp2YnNbbbdaHl31sCutxCGyHVtEtGnVpEJw4a8zbuKKltvmkshxHCczznzWfPkM8FZ7GMFsEbHEqYgZnkUqkzRSg4Rxpy0i6I3a50V6fsU-X_PrjlVZd7TKyuiyX83m_ar8vuFWLucmDjyxeDo59RJIknMRLwsX34Y7OGipDDP1kEHIKNsu14qgOSgOySyejFrVwnZLMKbS3aj0H9TcZ0z-E4LG9-Bb6HzLPPnRXze6b37v6Tre7Onuw1GHTMlJW-cB3LLVQzicdLn3R_DHk4fwiJjZosbXXre6s6Twi0zgV4msvAqsrQk6tScdEYcutviJoZE0C4T4s18EA4H_2WtVegVwvNe7y7Ppe4I11n5tLoLuU5UK21mqcvWRnJC5bVSkOtmUx3A1Prs8PY-65Rsik_C0wSnuQHMlDHNKJJprJalRFAvogOOOW4fwZaCF0dKr0iP2Eak0jMnUGJlynjyBgwq78wwIYlQ3LKjJhtKxQiVCWKmHIjWpU9ZkvAcfgvnyZavSkYfs-mSU71u7B2-CiXMcTT5Foiq7WNc5lRxdiQkpevC0Nfm2wURgOU6YeyB2nGFbwSt1755BE28Uu4NJj29-6Ws4nI7G-ddPF1-ew12K0Moz4Yb8BRw0q7V9idCo0a82Y-AvZLUO3A
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Routine+closed-suction+drainage+reduces+seromas+following+totally+extraperitoneal+%28TEP%29+inguinal+hernia+repair%3A+A+meta-analysis&rft.jtitle=Medicine+%28Baltimore%29&rft.au=Prassas%2C+Dimitrios&rft.au=Zaczek%2C+Michael&rft.au=David%2C+Stephan+Oliver&rft.au=Knoefel%2C+Wolfram+Trudo&rft.date=2024-03-15&rft.issn=0025-7974&rft.eissn=1536-5964&rft.volume=103&rft.issue=11&rft.spage=e37412&rft_id=info:doi/10.1097%2FMD.0000000000037412&rft.externalDBID=n%2Fa&rft.externalDocID=10_1097_MD_0000000000037412
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0025-7974&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0025-7974&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0025-7974&client=summon