Generation and analysis of 3D cell culture models for drug discovery

• Published in: European journal of pharmaceutical sciences Vol. 163; p. 105876
• Main Authors: Belfiore, Lisa, Aghaei, Behnaz, Law, Andrew M.K., Dobrowolski, Jeremy C., Raftery, Lyndon J., Tjandra, Angie D., Yee, Christine, Piloni, Alberto, Volkerling, Alexander, Ferris, Cameron J., Engel, Martin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2021
• Subjects: 3D cell culture; Bioprinting; Drug screening; Drug screening; Bioprinting; 3D cell culture; drug screening; bioprinting

Successful preclinical drug testing relies in part on data generated using in vitro cell culture models that recapitulate the structure and function of tumours and other tissues in vivo. The growing evidence that 3D cell models can more accurately predict the efficacy of drug responses compared to t...